94 results for “Reaction Department”, page 1 of 5
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Medical study · Medical research · 2011
Usefulness of Claudin 4 in the cytological diagnosis of serosal effusions
…peritoneum (6), were found to be positive. Claudin 4 was also extremely useful in detecting single-tumor cells dispersed among heavy inflammatory reaction. Because of its high sensitivity (99.1%) and specificity (100%), Claudin 4 might…
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Medical study · Medical research · 1989
Ultrastructural histochemistry of mesotheliomas and adenocarcinomas in malignant effusions
…along the outer surface of the cell aggregates, while carcinomas displayed a positive reaction either on the outer surface or on both inner and outer surfaces of the clusters. The diagnostic significance of the above-mentioned…
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Court case · Louisiana Court of Appeals · June 8, 1982 · in the opinion
White v. Johns-Manville Sales Corp. (1982)
…June 1948 until June 1980). During those years he worked in various departments of Johns-Manville including the transite pipe plant where he was exposed to asbestos fibers and silica, the asbestos shingle plant where he…
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Court case · Texas Court of Appeals · November 18, 1993 · in the opinion
Srite v. Owens-Illinois, Inc. (1993)
…in physical pain. Mr. Ben had been employed at the Petrotex Refinery in the labor department as an insulator. He worked on a daily basis as a sandblaster throughout his tenure at Petrotex, from 1958 until…
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Medical study · Medical research · 1987
Hydroxyl radical production in the presence of fibres by a Fenton-type reaction
…of people who inhale them. Results in the present study however indicate that these fibres are able to produce hydroxyl radicals in the presence of hydrogen peroxide by a Fenton-type reaction. Since hydroxyl radical is…
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Medical study · Medical research · 2006
Analysis of asbestos-induced gene expression changes in bronchiolar epithelial cells using laser capture microdissection and quantitative reverse transcriptase-polymerase chain reaction
…Extraction of RNA from microdissected tissue followed by quantitative reverse transcriptase-polymerase chain (QRT-PCR) reaction permits the analysis of cell-type or microstructure-specific gene expression changes that occur in response to various stimuli in…
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Medical study · Medical research · 1987
Response of mouse lung to crocidolite asbestos. 1. Minimal fibrotic reaction to short fibres
This was an animal experiment from the University of Manitoba, Winnipeg, on how mouse lungs respond to short crocidolite asbestos fibres. The authors separated short fibres from a standard UICC crocidolite sample. These had a mean length of 0.6…
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Medical study · Medical research · 2000
Tenascin expression and distribution in pleural inflammatory and fibrotic diseases
…as a marker of active pleural involvement. For this purpose we analyzed 71 histological samples of inflammatory and fibrotic pleura from patients with asbestos-induced pleural reaction (n = 6), postcardiac injury syndrome (n = 6…
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Medical study · Medical research · 2014
Positive FDG-PET/CT of the pleura twenty years after talc pleurodesis: three cases of benign talcoma
…This inflammatory reaction could decrease with time, as in other inflammatory processes. Since talc is not metabolized by the body, the FDG-PET scan can remain positive, most likely because of a foreign-body granulomatous reaction…
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Medical study · Medical research · 1992
Generation of hydroxyl radical by crocidolite asbestos is proportional to surface [Fe3+]
…in concentrations varying from 0 to 250 mM. Inclusion of deferoxamine in the reaction mixture provided similar results of diminishing both TBA reactive products and dihydroxybenzoic acid generation. We conclude that oxidant generation by crocidolite is…
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Medical study · Medical research · 1993
Activation of UICC crocidolite: the effect of conversion of some ferric ions to ferrous ions
…The amount of iron in asbestos fibers, its oxidation state, and its availability to specific chelating agents determine their ability to catalyze the aforementioned reactions. In the present study, the activation of UICC crocidolite was achieved…
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Medical study · Medical research · 2003
Asbestos bodies: clues to the mechanism of asbestos toxicity?
…lung, ascorbate was oxidized to oxalate in the presence of H2O2, a reaction inhibited by the iron chelator deferoxamine. The author called this a novel mechanism that may contribute to the pathogenicity of asbestos fibers. Oxidation…
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Medical study · Medical research · 2002
Early inflammatory response to asbestos exposure in rat and hamster lungs: role of inducible nitric oxide synthase
…inducible nitric oxide synthase (iNOS) plays a role in the development of asbestos-related pulmonary disorders. The pulmonary reactions of rats and hamsters upon exposure to asbestos fibers are well known to be disparate. In addition…
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Medical study · Medical research · 1983
Lipid peroxidation in microsomes induced by crocidolite fibres
…produced a concomitant induction in microsomal lipid peroxidation. This increase was very rapid as the reaction was almost complete within 10 min. The ability of these fibres to induce this process after a short period of…
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Medical study · Medical research · 2001
Study of inflammatory responses to crocidolite and basalt wool in the rat lung
…dehydrogenase (LDH) activity were determined in the bronchoalveolar lavage (BAL). Both types of fibers induced a prolonged inflammatory reaction in the lung. All the parameters studied in the experimental groups were more markedly elevated after 3…
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Medical study · Medical research · 1987
Enhanced lipid peroxidation and lysosomal enzyme activity in the lungs of rats with prolonged pulmonary deposition of crocidolite asbestos
…for example 75.87 versus 30.81 mg at three months), and microscopy showed granulomas containing fibres. The fibrotic reaction tended to diminish by seven months. Activity of two lysosomal enzymes, beta-glucuronidase and cathepsin D…
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Medical study · Medical research · 1987
Cytogenetic findings in an effusion secondary from pleural mesothelioma
…years earlier a similar episode had been diagnosed as tuberculous pleuritis. Routine examination of cells in the fluid showed only a nonspecific reaction of the lining cells, and a pleural biopsy found no signs of cancer…
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Medical study · Medical research · 2003
Ascorbic acid modifies the surface of asbestos: possible implications in the molecular mechanisms of toxicity
…consequence of the erosion of the outmost layers while hydration of silica tetrahedra yields new silanol groups. The activity in the Fenton-like reaction (OH from H(2)O(2)) decreases following surface iron depauperation. Conversely…
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Medical study · Medical research · 2010
Pleural granuloma mimicking malignancy 42 years after slurry talc injection for primary spontaneous pneumothorax
…malignant cells or asbestos fibers. Keyhole surgery was converted to open surgery and the pleura was removed. The pathologist diagnosed chronic granulomatous pleuritis caused by a foreign body reaction, likely talc. Only on detailed questioning did…
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Medical study · Medical research · 2001
Free radical generation in the toxicity of inhaled mineral particles: the role of iron speciation at the surface of asbestos and silica
…1.3 to 29 nmol/mg. It also increased one radical reaction, breaking a carbon-hydrogen bond, about 3-fold, while heating in air fully stopped that reaction. The other reaction, hydroxyl radical release from hydrogen…