9 results for “Reaction Department”
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Fenton Reaction
…around them in the lung) to chronic oxidative damage and carcinogenesis. Significance in Asbestos Context The Fenton Reaction is one of the leading biological mechanisms used to explain how asbestos fibers cause cancer at the cellular…
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Redox Cycling
Redox cycling is a repeating chemical reaction in which iron (or another metal) on the surface of an asbestos fiber alternates between two oxidation states, generating harmful reactive oxygen species such as hydroxyl radicals with each…
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Biologically Active Iron
…Ann Aust, and others, who showed that iron on asbestos fiber surfaces catalyzes the Fenton reaction, producing hydroxyl radicals that damage DNA and cell membranes. The term reflects the distinction between total iron content and the…
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Hydroxyl Radical
…and others showing that iron on fiber surfaces catalyzes hydroxyl radical formation through the Fenton reaction. Significance in Asbestos Context Hydroxyl radicals are central to the leading scientific explanation of how asbestos fibers cause disease at…
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Mixed-Valence Iron
…fibers, this coexistence of iron states is chemically important because it allows the fiber surface to drive reactions that generate harmful reactive oxygen species inside the body. Origin The concept comes from inorganic and mineral chemistry…
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Tyrosine Nitration
…oxidative stress. It serves as a measurable marker of the chronic tissue injury seen in asbestos-exposed lungs and pleura. Origin The reaction was characterized in the early 1990s by Joseph Beckman and colleagues, who showed…
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Desferrioxamine B
…Amphibole Asbestos, Iron-Catalyzed Oxidation, Free Radical Generation, Fenton Reaction Notes If your case involves amphibole exposure (crocidolite, amosite, tremolite) or asbestos-contaminated talc, ask whether your legal team's scientific experts address iron-mediated oxidative…
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Low-Molecular-Weight Iron Pool
…crocidolite fibers expanded the low-molecular-weight iron pool inside mesothelial cells, producing the oxidative DNA damage that eventually became the patient's pleural mesothelioma. Related Terms Reactive Oxygen Species, Fenton Reaction, Asbestos Body, Oxidative Stress…
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Iron Acquisition
…and accumulate iron atoms on their surface after entering the body. This loaded iron then drives chemical reactions that damage nearby cells and DNA. It is one of the leading scientific explanations for how a chemically…