VATS is a minimally invasive chest surgery in which a surgeon makes a few small incisions between the ribs and inserts a tiny video camera (thoracoscope) and specialized instruments to see and operate inside the chest cavity. It is used to diagnose, biopsy, and sometimes treat diseases of the lungs, pleura, and mediastinum, and it generally allows quicker recovery than traditional open-chest surgery.
Origin
Thoracoscopy dates back to Hans Christian Jacobaeus in 1910, who used it to break adhesions in tuberculosis patients. Modern VATS emerged in the early 1990s when miniaturized video cameras and improved endoscopic instruments allowed surgeons to perform complex chest procedures through small "port" incisions rather than a full thoracotomy.
Significance in Asbestos Context
VATS is one of the most important tools for diagnosing pleural mesothelioma and other asbestos-related pleural diseases. When imaging shows pleural thickening, nodules, or an unexplained pleural effusion, VATS allows the surgeon to directly view the pleural surface and take multiple, targeted biopsies, which is critical because mesothelioma can be patchy and easily missed by needle biopsy or fluid cytology alone. The tissue obtained at VATS is what pathologists use to confirm mesothelioma subtype (epithelioid, sarcomatoid, biphasic) and run the immunohistochemistry and BAP1/MTAP testing that drive treatment decisions and prognosis. VATS can also be therapeutic, draining trapped fluid, performing pleurodesis to prevent fluid reaccumulation, or, in selected patients, removing the diseased pleura (pleurectomy/decortication). The VATS operative report, pathology report, and any preserved tissue blocks are central pieces of medical evidence in a mesothelioma claim and should be carefully preserved.
Example Sentence
After a CT scan showed pleural thickening on his right side, the thoracic surgeon recommended VATS to obtain biopsies and confirm whether the patient had mesothelioma.
Related Terms
Pleural Biopsy, Pleurodesis, Pleurectomy/Decortication, Mesothelioma, Pleural Effusion, Immunohistochemistry
Notes
- Ask your surgeon how many biopsy samples will be taken and from how many areas of the pleura. Multiple, generously sized biopsies improve diagnostic accuracy for mesothelioma.
- Request that your pathology lab preserve the paraffin tissue blocks (not just slides); these may be needed for additional immunohistochemistry, BAP1/MTAP testing, or expert review by a mesothelioma specialty center.
- Get copies of the operative report, pathology report, and any intraoperative photos for your personal records and your legal team. These are core documents in an asbestos claim.
- If mesothelioma is suspected before surgery, ask whether the surgeon plans to do talc pleurodesis or close the port sites in a way that protects future treatment options, since some procedures can complicate later curative surgery.
- Consider seeking a second opinion at a high-volume mesothelioma center before VATS if your local hospital does not regularly diagnose this disease.
In the research library
54 studies in our medical research library mention Video-Assisted Thoracoscopic Surgery (VATS) in the title or abstract. Among the most cited:
- Mesothelioma--VATS biopsy and lung mobilization improves diagnosis and palliationM.W. Grossebner, A.A. Arifi, M. Goddard, et al, 1999 · European Journal of Cardio-thoracic Surgery · cited 27 times
- Australasian Malignant PLeural Effusion (AMPLE)-3 trial: study protocol for a multi-centre randomised study comparing indwelling pleural catheter (±talc pleurodesis) versus video-assisted thoracoscopic surgery for management of malignant pleural effusionD.B. Fitzgerald, C. Sidhu, C. Budgeon, et al, 2022 · Trials · cited 16 times
- Should all patients who have mesothelioma diagnosed by video-assisted thoracoscopic surgery have their intervention sites irradiated?M. Nagendran, A. Pallis, K. Patel, et al, 2011 · Interactive Cardiovascular and Thoracic Surgery · cited 14 times
- Comparison of video-assisted pleurectomy/decortication surgery plus hyperthermic intrathoracic chemotherapy with VATS talc pleurodesis for the treatment of malignant pleural mesothelioma: A pilot studyM. Migliore, M. Fiore, T. Filippini, et al, 2023 · Heliyon · cited 12 times
- The MesoVATS trial: is there a future for video-assisted thoracoscopic surgery partial pleurectomy?R.C. Rintoul, 2015 · Future Oncology · cited 8 times
The journals that publish most on it: General Thoracic and Cardiovascular Surgery (4), Cancers (3), Thoracic Cancer (2).
Category: Diagnostic Tools & Biomarkers · All Lexicon terms A–Z
This page is provided for general informational purposes and does not constitute legal advice. Every asbestos case turns on its own facts, exposure history, diagnosis, deadlines, available evidence, and applicable law. Reviewing this page does not create an attorney-client relationship. For advice about your specific situation, call 833-4-ASBESTOS for a free case review.