Case Reports in Gastroenterology

Our medical research library holds 6 studies published in Case Reports in Gastroenterology (2008–2026). Each entry links to the study's record on PubMed and, where there is one, to the publisher's page and a free full text. 6 have an abstract, the authors' own summary as PubMed records it: open "Abstract" to read it.

About the journal

• Publisher: Karger
• Published: 2007 to the present, Switzerland
• Language: English
• ISSN: 1662-0631 (electronic)
• Its record in the NLM Catalog

2020s

• Long-Term Remission of Peritoneal Lymphangiomatosis with Sirolimus Therapy: A Case Report with 8-Year Follow-Up. P. Jovanovic, E. Zerem, M. Basic Denjagic, et al. 2026;20(1):8-15. Case report PubMed · Publisher · Free full text

  Abstract

  Introduction: Peritoneal lymphangiomatosis is a rare benign lymphatic disorder with diagnostic and therapeutic challenges. It may mimic peritoneal carcinomatosis or mesothelioma, often requiring histological confirmation. Management options are limited, and long-term data on targeted therapies, including sirolimus, remain scarce.

  Case Presentation: We present the case of a 45-year-old woman with a history of surgically corrected atrial septal defect, who developed progressive abdominal distension and dysuria in May 2014. Abdominal ultrasound and contrast-enhanced abdominal computed tomography revealed diffuse ascites, peritoneal thickening, and cystic changes. Diagnostic uncertainty led to an exploratory laparotomy in May 2015, where histopathology confirmed peritoneal lymphangiomatosis. After failed conservative management including dietary modification, diuretic therapy, and repeated paracenteses, she was started on sirolimus 2 mg/day in August 2016. Her serum trough levels were maintained between 5 and 15 ng/mL. She achieved a Karnofsky Performance Score of 100% (indicating full functional capacity) within 2 months and has remained in complete clinical and radiologic remission for over 8 years. Diabetes mellitus type 2 was diagnosed during follow-up and is well controlled with insulin therapy.

  Conclusion: This case underscores the difficulty of diagnosing peritoneal lymphangiomatosis and highlights the transformative potential of sirolimus therapy. To our knowledge, this is one of the longest documented remissions of peritoneal lymphangiomatosis under mechanistic target of rapamycin (mTOR) inhibition.

  © 2025 The Author(s). Published by S. Karger AG, Basel.

• Primary Peritoneal Mesothelioma: Diagnostic Challenges of This Lethal Imposter. S.K. Dusseault, O.E. Okobi, N. Thakral, et al. 2022;16(3):588-594. Case report PubMed · Publisher · Free full text

  Abstract

  Primary Peritoneal Mesothelioma is a rapidly aggressive and rare neoplasm that arises from the lining of mesothelial cells of the peritoneum and spreads extensively within the confines of the abdominal cavity. The pathogenesis of all forms of mesothelioma is strongly associated with industrial pollutants, of which asbestos is the principal carcinogen. Characteristically, asbestos exposure has a strong relationship with mesothelioma of the pleura, but the peritoneal cavity is the second most commonly affected site. Additionally, in contrast to pleural mesothelioma, which has a male predominance (male-female ratio of between four and five to one), women comprise approximately one-half of all cases of malignant peritoneal mesothelioma. A thorough history of occupational/paraoccupational exposure along with histopathology is the key to timely diagnosis and treatment.

  Copyright © 2022 by The Author(s). Published by S. Karger AG, Basel.

2010s

• An Unusual Cause of Abdominal Ascites. K.A. Wong, K.A. Olson, E.W. Chak. 2018;12(2):420-424. Case report PubMed · Publisher · Free full text

  Abstract

  Abdominal ascites is most commonly caused by portal hypertension from liver cirrhosis. When present, portal hypertension is associated with an elevated serum-ascites albumin gradient (SAAG) ≥1.1 g/dL. In contrast, a SAAG < 1.1 g/dL suggests malignancy, tuberculosis, pancreatitis, or nephrotic syndrome. Here, we present a case of low SAAG ascites caused by epithelioid peritoneal mesothelioma in a woman with no known liver disease. The diagnosis proved elusive until diagnostic laparoscopy with biopsy was performed.

• Benign Cystic Mesothelioma Misdiagnosed as Peritoneal Carcinomatosis. H.D. Shin, S.B. Kim. 2016;10(1):115-20. Case report PubMed · Publisher · Free full text

  Abstract

  Benign cystic mesothelioma (BCM) is a rare benign disease that forms multicystic masses in the abdomen, pelvis, and retroperitoneum. It occurs predominantly in young to middle-aged women. The majority of cases were associated with a history of abdominal or pelvic operation, a history of endometriosis, and pelvic inflammatory disease. We present a unique case of BCM which is different to the previous cases. The patient was a 52-year-old man showing features of peritoneal carcinomatosis accompanied by ascites on abdominal computed tomography scans. We herein report a case of BCM misdiagnosed with peritoneal carcinomatosis.

• Malignant Peritoneal Mesothelioma Mimicking Ischemic Colitis. Y. Mitsuka, S. Yamazaki, T. Miyakuni, et al. 2010;4(2):238-242. Case report PubMed · Publisher · Free full text

  Abstract

  The prognosis of malignant peritoneal mesothelioma is extremely poor with a mean survival time of 12 months. The initial symptoms are poor and atypical. Because of its rare entity and little knowledge of its treatments, there are few reports of long-term survival. We encountered a very unique case with strong impression on radiological findings of malignant peritoneal methothelioma. We had misdiagnosed it because of the findings and because the time course was similar to that of ischemic colitis. The radiological findings on CT and enema disappeared within one week after antibiotic therapy.

2000s

• A rare case of peritoneal sarcoidosis in a 36-year-old construction worker. S. Chubineh, K. Katona. 2008;2(3):369-72. Case report PubMed · Publisher · Free full text

  Abstract

  A 36-year-old man was admitted for persistent abdominal pain and weight loss. He had had significant exposure to asbestos, as he had been active in cleanup after the World Trade Center attack. A CT scan of his abdomen was initially read as peritoneal carcinomatosis without evidence of ascites. Infectious etiology was subsequently ruled out and diagnostic laparoscopy was performed for tissue diagnosis revealing noncaseating granulomas consistent with peritoneal sarcoidosis. Of note, he had an elevated CA-125 level on admission, which is unique in males with peritoneal sarcoidosis.

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