Clinical Nuclear Medicine

Our medical research library holds 26 studies published in Clinical Nuclear Medicine (1980–2024). Each entry links to the study's record on PubMed and, where there is one, to the publisher's page and a free full text. 23 have an abstract, the authors' own summary as PubMed records it: open "Abstract" to read it. For 2 studies PubMed has no abstract for, we give the abstract printed in the article or, where there is none, a summary we wrote from it, each labeled as such.

About the journal

• Publisher: Lippincott
• Published: 1976 to the present, United States
• Language: English
• ISSN: 0363-9762 (print), 1536-0229 (electronic)
• Its record in the NLM Catalog

2020s

• Epithelial Malignant Pleural Mesothelioma Mimics Lymphoma on 18 F-FDG PET/MRI : A Case Report. T. Tian, H. Xie, M. Huang. 2024;49(4):359-360. Case report PubMed · Publisher

  Abstract

  Malignant pleural mesothelioma is a rare tumor with a poor prognosis. We describe a case of 55-year-old man without asbestos exposure history presenting with extensive lymph nodes with high 18 F-FDG uptake in PET/MRI but atypical pleural manifestations thereby being misdiagnosed for lymphoma. Pathological examination concludes for an epithelioid mesothelioma-associated lymph node metastasis. This case emphasizes that with the extensive lymph node abnormalities shown in PET imaging, in addition to the general consideration of lymphoma, it is still necessary to be vigilant about the possibility of mesothelioma and emphasizes the necessity of pathological examination.

  Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.

• 18F-FDG Uptake of Localized Malignant Peritoneal Mesothelioma. E. Kodama, T. Kodama, T. Ichikawa, et al. 2020;45(2):161-163. Case report PubMed · Publisher

  Abstract

  We present 2 cases of malignant peritoneal mesothelioma (MPM) characterized by a localized solid mass without ascites and showing F-FDG uptake. A 79-year-old man with a history of asbestos exposure suffered from an epithelioid MPM originating from the hepatoduodenal ligament with FDG uptake (SUVmax 16.8). Another 80-year-old man with esophageal cancer showed desmoplastic MPM of the small bowel mesentery with FDG uptake (SUVmax 4.0). Desmoplastic MPM is more aggressive and yields poorer prognosis compared with the epithelioid type. However, the present desmoplastic MPM case showed mild FDG uptake because of rich fibrosis.

• 99mTc-HDP Bone Scintigraphy, SPECT/CT, and 18F-FDG PET/CT Diagnosis Imaging of Incidental Pleural Mesothelioma in a Patient With Biochemical Recurrences of Prostate Cancer: Is it Really a Coincidence?. P. Fernández-Rodríguez, J.J. Martín-Marcuartu, I. Acevedo Báñez, et al. 2020;45(3):e148-e150. Case report PubMed · Publisher

  Abstract

  We present the case of a 69-year-old man with history of prostate carcinoma treated with prostatectomy and subsequently with external beam radiotherapy and hormone therapy because of biochemical recurrences. More than 10 years after the diagnosis, follow-up Tc-HDP bone scans and SPECT/CT images demonstrated an incidental diagnosis of osteoblastic pleural plaques that quickly evolve to mesothelioma. PET/CT achieved the definitive diagnosis by guiding the biopsy to the highest and most accessible focus of glucidic hypermetabolism. Our case report raises the association between prostate cancer patients treated with external beam radiotherapy and the development of pleural mesothelioma despite having no history of exposure to asbestos.

• A Case of Localized Malignant Peritoneal Mesothelioma Evaluated by 18F-FDG PET/CT. T. Xu, J. Hu, X. Zhang, et al. 2020;45(11):890-891. Case report PubMed · Publisher

  Abstract

  Localized malignant mesothelioma is rare. The prognosis is generally more favorable for this condition than for diffuse malignant mesothelioma. An elderly woman recently complained of abdominal pain, fever, and weight loss. She had no history of asbestos exposure. Her serum CEA level was elevated. Plain CT revealed a mass under the left diaphragm, with liquefaction and necrosis. A contrast-enhanced scan showed circular enhancement of the mass. A subsequent biopsy of the mass revealed a poorly differentiated carcinoma. PET/CT showed a significant FDG-avid subphrenic mass without any indications of metastasis. Postoperative pathological and immunohistochemical examination confirmed a case of malignant mesothelioma.

• A Case of Localized Malignant Peritoneal Mesothelioma With Lung Cancer Detected by 18F-FDG PET/CT. S. Kobayashi Shimizu, T. Okamura, K. Koyama, et al. 2020;45(10):795-797. Case report PubMed · Publisher

  Abstract

  A 62-year-old woman was referred for cough and lower abdominal pain. F-FDG PET/CT showed strong uptake not only in the left lung mass and hilar and mediastinal lymph nodes, but also a huge lower abdominal mass. All lesions were initially thought to be multiple metastases because bronchial biopsy of the lung mass showed poorly differentiated adenocarcinoma. However, the abdominal mass was found to be malignant peritoneal mesothelioma after surgical resection. It was difficult to diagnose this case correctly before resection because localized malignant peritoneal mesothelioma is rare.

2010s

• 18F-FDG PET/CT Findings of Ovarian Mesothelioma: A Case Study. R. Sun, Y. Chen, Z. Huang. 2019;44(11):925-926. Case report PubMed · Publisher

  Abstract

  Ovarian mesothelioma is a rare and aggressive tumor. Early diagnosis of the disease is difficult, delaying effective treatment. Here we report a 50-year-old woman who was referred for an F-FDG PET/CT imaging to assess her newly detected left ovarian mass. The images not only demonstrated a hypermetabolic mass in the left ovary, but also several hepatic low densities with increased FDG uptake, which suggested ovarian malignancy with hepatic metastases. Mesothelioma was diagnosed histopathologically following the biopsy. Our case demonstrates PET/CT findings observed in ovarian mesothelioma.

• 18F-FDG PET/CT Revealing Constrictive Pericarditis as the Only Manifestation of Malignant Mesothelioma. J.P. Edel, H. Balink. 2019;44(1):55-56. Case report PubMed · Publisher

  Abstract

  A 57-year-old man presented with shortness of breath and ankle edema. Constrictive pericarditis with an unexplained mass surrounding the heart was diagnosed by ultrasound. Accordingly, F-FDG PET/CT was performed. Multiple PET-positive noduli and irregular tissue were located in the pericardium, with pleural fluid present, but without additional pulmonic or pleural pathology. A pericardiectomy was successfully performed. Histopathology and immunohistochemical staining revealed epithelioid mesothelioma.

• Focal Peritoneal Mesothelioma Demonstrated on FDG PET/CT. J. Xiao, H. Yin, D. Cheng, et al. 2019;44(11):886-888. Case report PubMed · Publisher

  Abstract

  A 48-year-old woman was experiencing abdominal pain and melena for 3 months. Because of these symptoms combined with increased level of tumor marker CA125, possible abdominal malignancy was considered, and an FDG PET/CT was performed to assess occult tumor. The images revealed multiple hypermetabolic lesions along the peritoneal surface. Pathological examination after biopsy demonstrated low-grade epithelioid peritoneal mesothelioma.

• Peritoneal Deciduoid Malignant Mesothelioma on 67Ga SPECT/CT. Y.C. Lai, Y.C. Wu, C.H. Kao, et al. 2019;44(2):161-163. Case report PubMed · Publisher

  Abstract

  Malignant mesotheliomas may be classified into epithelioid (60%), sarcomatoid (20%), or mixed (20%) type microscopically. Malignant deciduoid mesothelioma, a rare phenotype of epithelioid mesothelioma, arises more commonly from the peritoneum of young women, but is also from the pleura of elderly people. In the current report, the authors describe an unusual case of peritoneal malignant epithelioid mesothelioma with rare deciduoid phenotype demonstrated with Ga SPECT/CT.

• Pleural Mesothelioma Detects by 18F-Choline PET/CT in a Patient With Biochemical Recurrence of Prostate Cancer. M. Rensi, G. Ferretti, F. Di Gregorio, et al. 2019;44(2):e116-e117. Case report PubMed · Publisher

  Abstract

  A 73-year-old man with a prostate cancer treated by radical prostatectomy in 2006. For a biochemical recurrence of disease (prostate-specific antigen level, 0.1 ng/mL) during hormonal therapy, patient underwent F-choline PET/CT that showed a significant uptake in a diffuse right pleural thickening. The patient was sent to pleurectomy decortication showing an epithelioid pleural mesothelioma. This case highlighted that a histopathological evaluation is mandatory in case of a significant radiolabeled choline uptake in pleural lesions.

• Malignant peritoneal mesothelioma with lower extremity metastasis: PET/CT imaging. B.B. Le, B.D. Nguyen. 2015;40(1):e68-70. Case report PubMed · Publisher

  Abstract

  Malignant peritoneal mesothelioma is usually confined to the abdomen and pelvis. Extra-abdominal and extrapelvic dissemination is very uncommon mostly at advanced stages of the disease. This rare clinical event may be related to contiguous spread through connecting pathways linking the abdomen and pelvis to the thorax and proximal lower extremity. The authors present a case of advanced malignant peritoneal mesothelioma with contiguous dissemination to the right thigh and proximal leg documented and monitored by F-FDG PET/CT imaging.

• Benign cystic mesothelioma: false-positive iodine accumulation in a patient with oncocytic follicular thyroid carcinoma. M. Meyer, Y. Godbert, I. Soubeyran, et al. 2014;39(9):e395-7. Case report PubMed · Publisher

  Abstract

  Whole-body (131I) scintigraphy (WBS) is used to detect residual or metastatic tissue during treatment of differentiated thyroid carcinoma in combination with thyroglobulin (Tg) and ultrasonography of the neck. It is a highly sensitive method, but there is a high rate of false positives. We report the case of a 52-year-old woman with false-positive iodine accumulation in a benign cystic mesothelioma discovered during treatment for a oncocytic follicular thyroid carcinoma (stage pT2 pNx Mx). This lesion was detected by WBS and confirmed by surgery and histopathologic analysis.

• Multiple primary hepatic malignant mesotheliomas mimicking cystadenocarcinomas on enhanced CT and FDG PET/CT. A. Dong, H. Dong, C. Zuo. 2014;39(7):619-22. Case report PubMed · Publisher

  Abstract

  A 50-year-old woman presented with upper abdominal pain for 2 months. Abdominal enhanced CT showed multiple hypodense cystic tumors in the liver with heterogeneous enhanced septations. FDG PET/CT showed hypermetabolic peripheral regions and internal septations of the tumors with SUVmax of 6.3. Multiple hepatic cystadenocarcinomas were suspected. The patient underwent resection of the tumors. Epithelial mesothelioma was confirmed by pathology. This case indicates primary hepatic mesothelioma should be added to the differential diagnosis of FDG-avid malignant hepatic tumors.

• PET/CT demonstration and monitoring of thoracic and abdominal wall mesothelioma. B.D. Nguyen. 2014;39(1):e106-9. Case report PubMed · Publisher

  Abstract

  Mesothelioma is a malignancy arising from the embryonic coelomic mesodermal lining forming the pleura, peritoneum, pericardium, and tunica vaginalis. It is mostly induced by exposure to asbestos. The author presents a 77-year-old woman with an atypical manifestation of epithelioid mesothelioma, which does not follow the expected clinical characteristics of this disease mentioned above. In this case, PET/CT provides useful information concerning the extension of the lesions to thoracic and abdominal walls not fully evaluated by the initial conventional cross-sectional imaging. PET/CT also allows an accurate therapeutic monitoring of the disease.

• Scrotal peritoneal mesothelioma on PET/CT. S. Ozguven, M. Aras, F. Dede, et al. 2014;39(12):1045-6. Case report PubMed · Publisher

  Abstract

  Although malignant mesothelioma originating from the tunica vaginalis has been reported in the literature, direct invasion of malignant peritoneal mesothelioma to the scrotal cavity has not been described yet. Herein, we presented a diffuse malignant peritoneal mesothelioma extending inferiorly to the scrotum via inguinal canal detected on FDG PET/CT.

• Role of 18F-FDG PET/CT in the staging of pediatric peritoneal mesothelioma. G. Abikhzer, K. Gourevich, M. Arkovitz, et al. 2013;38(8):e331-2. Case report PubMed · Publisher

  Abstract

  A 7-year-old girl with a 1-month history of diffuse abdominal pain underwent an ultrasound which showed a pelvic mass with multiple peritoneal implants and ascites. An US-guided core biopsy of one of the implants as well as a transrectal biopsy of the pelvic tumor showed pathological findings consistent with epithelioid mesothelioma. We describe the findings on (18)F-FDG PET/CT in pediatric peritoneal mesothelioma.

• 18F-FDG PET/CT in a recurrent diffuse malignant peritoneal mesothelioma. Q. Cao, M. Lu, J. Heath, et al. 2012;37(5):492-4. Case report PubMed · Publisher

  Abstract

  Peritoneal mesothelioma is a rare and aggressive tumor. Early diagnosis of the disease is difficult, delaying effective treatment. We report a case of recurrent, biphasic, diffuse, malignant peritoneal mesothelioma. Initial abdominal computed tomography showed abnormal but nonspecific findings suggestive of an ovarian malignancy, with a negative endoscopy and laboratory studies. An abdominal exploratory laparotomy found widespread malignancy within the peritoneum with a pathological diagnosis of peritoneal mesothelioma. A PET/CT imaging showed diffusely increased metabolic activity throughout the peritoneum, with no evidence of thoracic or pleural involvement. This case demonstrates the PET/CT findings seen with malignant recurrent peritoneal mesothelioma.

• A case of primary pericardial mesothelioma detected by 18F-FDG PET/CT. F. Aga, Y. Yamamoto, T. Norikane, et al. 2012;37(5):522-3. Case report PubMed · Publisher

  Abstract

  Primary pericardial mesothelioma is an extremely rare malignancy. We report a case of a 58-year-old woman who presented with fever and fatigue. She had no apparent history of occupational or incidental exposure to asbestos. A postcontrast-enhanced chest CT revealed a 77 × 56-mm mass lesion in the pericardium. The FDG PET/CT was carried out, which demonstrated an intense FDG uptake to a main pericardial tumor and disseminated lesions in the pericardium. Histologic examination confirmed the primary malignant pericardial mesothelioma.

• Incarcerated inguinal hernia from metastatic pleural mesothelioma: PET/CT imaging. V.X. Nguyen, B.D. Nguyen, P.C. Ram, et al. 2012;37(5):e117-8. Case report PubMed · Publisher

  Abstract

  PET/CT provides a comprehensive staging, post-therapeutic surveillance, and outcome prognosis of malignant pleural mesothelioma based on its hypermetabolic behavior. This ability of PET may allow the monitoring, prediction, and detection of uncommon distant gastrointestinal clinical manifestations of this disease. The authors present a case of PET/CT imaging of pleural mesothelioma disseminating to the abdomen and pelvis, inducing an incarcerated inguinal hernia.

• Sarcomatoid carcinoma (carcinosarcoma) of the lung mimics malignant pleural mesothelioma on 18F-FDG PET/CT: a report of 2 cases. A. Ciarallo, W. Makis, J.A. Novales-Diaz, et al. 2012;37(4):416-9. Case report PubMed · Publisher

  Abstract

  Sarcomatoid carcinomas of the lung account for less than 0.4% of all lung tumors, and they are a heterogeneous group of non–small-cell lung carcinomas containing a sarcoma or sarcoma-like component. They have a poor prognosis, with an overall 5-year survival of 25% compared with 45% for other types of non–small-cell lung carcinomas. The literature on the use of 18F-FDG PET/CT to stage these tumors is very limited, and their PET/CT imaging characteristics have not been previously described. We report on 2 cases of sarcomatoid carcinoma that resembled malignant pleural mesothelioma on 18F-FDG PET/CT and were correctly staged.

  PubMed has no abstract for this study. This is the authors' abstract, copied from the article.

2000s

• Primary malignant peritoneal mesothelioma: appearance on F-18 FDG positron emission tomographic images. T.N. Eade, M.J. Fulham, C.J. Constable. 2002;27(12):924-5. Case report PubMed · Publisher

  Abstract

  A case of primary peritoneal mesothelioma is reported with fluorodeoxyglucose (FDG) positron emission tomography (PET). A 68-year-old man with known asbestos exposure had vague right upper quadrant pain and an abdominal mass. Biopsy showed a malignant peritoneal mesothelioma. He subsequently underwent an FDG-PET scan. Peritoneal mesothelioma is a rare disorder that usually presents in its end stage with nonspecific abdominal pain and less frequently with signs of bowel obstruction. It is the only primary cancer of the peritoneal surface.

  PubMed has no abstract for this study. This is the authors' abstract, copied from the article.

• Unilateral Ga-67 uptake in the hemithorax after recurrence of pleural effusion. G. Panoutsopoulos, K. Syrigos, I. Ilias, et al. 2001;26(11):983-4. Case report PubMed · Publisher

1990s

• Uptake of In-111 pentetreotide by pleural plaques. M. Lonneux, F. Jamar, N. Leners, et al. 1998;23(5):298-301. Case report PubMed · Publisher

  Abstract

  Somatostatin receptor imaging with In-111 pentetreotide has been validated for the diagnosis and staging of chest tumors with neuroendocrine differentiation such as bronchial carcinoid and small cell lung cancer. In-111 pentetreotide uptake is not specific for neuroendocrine tumors because somatostatin receptors are also expressed by white blood cells, leading to the in vivo visualization sites of infection sites or active inflammation. Pleural plaques may be due to asbestos exposure or tuberculosis. Presented here are three cases of In-111 pentetreotide uptake in pleural plaques. This uptake by benign lesions may be misleading in the diagnostic work-up of patients with lung tumors.

• P-32 bremsstrahlung SPECT helps assess intracavitary therapy. B. Petri, R. Nance, J. Hanada, et al. 1992;17(9):709-10. Case report PubMed · Publisher

  Abstract

  A patient underwent intracavitary P-32 chromic phosphate therapy for a chest tumor. Tc-99m sulfur colloid instilled before the P-32 demonstrated uniform distribution of activity throughout the right pleural space, and the P-32 was immediately administered. Ten days later, SPECT imaging using bremsstrahlung radiation of the P-32 showed an unexpected loculation of the P-32. A subsequent chest CT scan demonstrated pleural infolding and fluid localization in the same area as the P-32, indicating that the bremsstrahlung SPECT study had, in fact, documented the final localization of the P-32, which was unexpected and different from the initial localization. The procedure used in this case may be of value in documenting the ultimate distribution of intracavitary P-32.

1980s

• Unexpected gallium uptake in benign pulmonary pathology. Report of two cases. R.G. McLean, D. Choy, I.P. Murray. 1984;9(12):675-8. Case report PubMed · Publisher

  Abstract

  Two cases in which pulmonary gallium uptake was demonstrated in benign conditions are reported. In one, the abnormality permitted localization of a benign mesothelioma, while in the other patient it was associated with pulmonary fibrosis resulting from therapeutic irradiation. These cases extend the causes of gallium accumulation in which neither malignancy nor infection is responsible.

• Demonstration of pleural mesothelioma by gallium scan. I.S. Seo, K.G. Joo, J.E. Carter. 1980;5(9):407-9. Case report PubMed · Publisher

  Abstract

  A case of malignant mesothelioma is presented with marked radionuclide accumulation in the periphery of the hemithorax on Ga-67 imaging.

Browse every journal in the library or the library by type of article, or return to medical research.