Our medical research library holds 7 studies published in Journal of Pediatric Surgery (1983–2018). Each entry links to the study's record on PubMed and, where there is one, to the publisher's page and a free full text. 7 have an abstract, the authors' own summary as PubMed records it: open "Abstract" to read it.
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About the journal
- Publisher: Saunders
- Published: 1966 to the present, United States
- Language: English
- ISSN: 0022-3468 (print), 1531-5037 (electronic)
- Its record in the NLM Catalog
2010s
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Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for disseminated intra-abdominal malignancies in children-a single-institution experience. O. Zmora, A. Hayes-Jordan, A. Nissan, et al. 2018;53(7):1381-1386. PubMed · Publisher
Abstract
Purpose: Our purpose was to present our institutional experience with performing complete cytoreduction surgery and heated intraoperative chemotherapy (CRS-HIPEC) for children with disseminated intraabdominal malignancies, guided by a leading international center performing CRS-HIPEC in children.
Methods: Retrospective chart review of all cases of CRS-HIPEC in children in our institution, examining diagnosis, preoperative management, operative management, postoperative treatment, short term outcome including length of stay and complications, and long term outcome including survival and recurrence of disease.
Results: 9 children underwent CRS-HIPEC over 48months. The mean age of the patients was 8years. Tumors were: rhabdomyosarcoma (RMS), mesothelioma, Sertoli-Leydig, desmoplastic small round cell tumor, colon carcinoma and Wilms' tumor. Most patients received intraperitoneal cisplatin. Short term outcome was very good with median length of hospital stay of 13days and low rate of complications. Seven patients were alive at last follow up. Five patients developed a recurrent disease. Recurrence was intraabdominal in two of these patients.
Conclusions: CRS-HIPEC for children with disseminated intraabdominal malignancies performed in a dedicated institution and with guidance by a leading international center can be performed safely.
Type Of Study: Treatment study.
Level Of Evidence: IV.
Copyright © 2017 Elsevier Inc. All rights reserved.
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Benign cystic mesothelioma of the peritoneum in a male child. Z. Stojsic, R. Jankovic, B. Jovanovic, et al. 2012;47(10):e45-9. Case report PubMed · Publisher
Abstract
The benign cystic mesothelioma of the peritoneum is a rare lesion that occurs predominatly in women of reproductive age and has a high propensity for local recurrence. It is very rare in childhood, especially in boys, being reported in only 4 cases. A new case of benign cystic mesothelioma of the peritoneum in an 11-year-old boy is reported. The lesion occupied the entire left abdomen, arising from the transverse mesocolon, and it was accompanied by 4 small cysts. The patient had a coexistent right-sided renal agenesis. The mesothelial nature of the cysts epithelial lining cells was confirmed by immunopositivity for calretinin, cytokeratin 5/6, HBME1, and epithelial membrane antigen (EMA). No recurrence of the lesion was noted in the 7-month follow-up. Pathologists and clinicians should be aware of the existence of this rare entity in childhood to establish an accurate diagnosis and provide close follow-up after the surgery.
Copyright © 2012 Elsevier Inc. All rights reserved.
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Unusual cases: melanomatosis and nephroblastomatosis treated with hyperthermic intraperitoneal chemotherapy. A. Hayes-Jordan, H. Green, V. Prieto, et al. 2012;47(4):782-7. Case report PubMed · Publisher
Abstract
Hyperthermic intraperitoneal chemotherapy (HIPEC) is a well-established therapy for carcinomas, mesotheliomas, and some sarcomas. However, HIPEC has not been reported in melanomatosis or nephroblastomatosis. Here we present 2 unique cases of cytoreductive surgery and HIPEC. Cytoreductive surgery followed by HIPEC was performed in a 4-year old with melanomatosis and a 12-year old with nephroblastomatosis. A 4-year-old girl presented with leptomeningeal melanoma that metastasized from a congenital nevus. She had a ventricular peritoneal shunt placed as an infant. Melanomatosis involving the meninges and peritoneal surfaces was identified by positron emission tomographic scan imaging. Extensive plaques of melanoma were removed at the time of surgery, followed by HIPEC. She had no significant postoperative complications. Her abdomen remained free of disease 7 months after treatment. A 13-year-old girl presented with a Wilms' tumor at age 10 years. She then presented to us at the second local recurrence with multiple intraabdominal tumor implants (ie, nephroblastomatosis). We performed cytoreductive surgery followed by HIPEC. She had no postoperative complications and, at 1 year post-HIPEC, had no abdominal recurrence. We conclude that HIPEC can be performed safely for rare diseases such as melanomatosis and nephroblastomatosis. Although abdominal disease control can be realized, further systemic treatment options are necessary. A review of indications for HIPEC is included.
Published by Elsevier Inc.
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Benign cystic mesothelioma of the peritoneum in a child-case report and review of the literature. V.C. Shakya, C.S. Agrawal, S. Karki, et al. 2011;46(4):e23-e26. Case report PubMed · Publisher
Abstract
A 4-year old female child presented with clinical features of ascites that, on computed tomography, showed a huge thin-walled cystic lesion in the peritoneum. Laparotomy confirmed a unilocular cyst in the peritoneum adhered to the parietal wall and bowel but not originating from any internal organs. Histopathologic examination of the cyst wall was consistent with the diagnosis of benign mesothelioma. Benign cystic mesothelioma of the peritoneum has rarely been reported in children.
Copyright © 2011 Elsevier Inc. All rights reserved.
1980s
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Paratesticular malignant mesothelioma associated with abdominoscrotal hydrocele. A.L. Velasco, J. Ophoven, J.R. Priest, et al. 1988;23(11):1065-7. Case report · Review PubMed · Publisher
Abstract
This is the report of 14-year-old boy with a malignant mesothelioma of the tunica vaginalis contained in an abdominoscrotal hydrocele. A review of the literature shows that this aggressive tumor is very rare and has been reported only in adults.
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Malignant peritoneal mesothelioma in children: description of two cases and review of the literature. M. Kovalivker, A. Motovic. 1985;20(3):274-5. Case report PubMed · Publisher
Abstract
Malignant peritoneal mesothelioma (MPM) in children has been rarely described in the literature. During the last 10 years we have seen 2 cases. The first was a 2-year-old boy who died 3 months after surgery. The second is now alive two and a half years after the mesothelioma was found, has undergone 3 laparotomies for recurrent tumor, and is now receiving chemotherapy and is apparently free of tumor.
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Congenital peritoneal mesothelioma. M.J. Silberstein, J.E. Lewis, J.D. Blair, et al. 1983;18(3):243-5. Case report PubMed · Publisher
Abstract
Only three primary peritoneal mesotheliomas in children have been previously reported. We describe a 6-wk-old girl with a papillary peritoneal mesothelioma of low grade malignancy. This is probably a congenital mesothelioma and is the youngest patient reported to date.
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