Postgraduate Medicine

Our medical research library holds 6 studies published in Postgraduate Medicine (1971–2012). Each entry links to the study's record on PubMed and, where there is one, to the publisher's page and a free full text. 5 have an abstract, the authors' own summary as PubMed records it: open "Abstract" to read it.

About the journal

• Publisher: Informa Healthcare
• Published: 1947 to the present, England
• Language: English
• ISSN: 0032-5481 (print), 1941-9260 (electronic)
• Absorbed: Interstate Postgraduate Medical Association of North America. International Assembly. Proceedings of the International Assembly of the Inter-state Post-graduate Medical Association of North America
• Absorbed: e.MD
• Its record in the NLM Catalog

2010s

• Asbestos-related pleuropulmonary diseases: benign and malignant. A. Lazarus, A. Massoumi, J. Hostler, et al. 2012;124(3):116-30. Review PubMed · Publisher

  Abstract

  Asbestos is known for its desirable properties of thermal and heat resistance along with excellent strength and durability. It was widely used in many industries since the late 19th century, until its adverse effects on health were recognized. The occurrence of pleuropulmonary changes from exposure to asbestos often has a latency period of 20 to 30 years. The use of asbestos has been banned, regulated, and minimized in many countries, but in several developing countries, the use of asbestos in industries is still a common practice. In this article, the benign and malignant clinical manifestations of asbestos exposure are discussed.

• Inflammasome-mediated autoinflammatory disorders. S.P. Wilson, S.L. Cassel. 2010;122(5):125-33. Review PubMed · Publisher · Free full text

  Abstract

  The nucleotide-binding domain leucine-rich repeat containing (NLR) family of receptors are members of the innate immune system, and have a critical role in host defense. These molecules are key to driving inflammatory responses to abnormal cellular conditions. Many NLRs serve this role on activation by forming a multiprotein complex called an inflammasome. The inflammasome drives the processing and release of cytokines, such as the proinflammatory cytokines interleukin (IL)-1β and IL-18. Recently, the important function of NLR molecules in autoinflammatory disorders has been recognized, in part through the identification of the role of IL-1β in the pathogenesis of several autoinflammatory diseases. Cryopyrin-associated periodic syndromes were the first autoinflammatory disorders found to be directly mediated by dysfunctional inflammasome activation. This finding has subsequently led to studies in both murine models and humans that have revealed several other inflammatory conditions associated with activation of NLR-containing inflammasomes. Understanding the molecular pathophysiology of these autoinflammatory disorders has further guided the successful development of targeted therapy against IL-1. In this review, we provide an overview of the inflammasomes and describe the important role they play in the development and manifestation of autoinflammatory diseases.

2000s

• Strategies in lung cancer detection. Achieving early identification in patients at high risk. J.J. Bechtel, T.L. Petty. 2003;114(2):20-6. Review PubMed · Publisher

  Abstract

  Screening can be crucial for timely identification of lung cancer and thus for early treatment and a favorable prognosis. This conclusion is true particularly for persons at high risk for lung cancer, including those exposed to asbestos or silicon dust. In this article, Drs Bechtel and Petty discuss the types of screening procedures available, their cost, and the approaches and timing that are most beneficial to the public as a whole.

1980s

• Asbestos exposure. An update on pleuropulmonary hazards. B. Varkey. 1983;74(4):93-9, 102-3. PubMed · Publisher

  Abstract

  Asbestos exposure is causally related to the development of asbestosis, bronchogenic carcinoma, malignant mesothelioma, and nonmalignant pleural disorders. Clinical and roentgenographic manifestations of asbestosis mimic other diffuse fibrotic lung diseases. However, a concomitant finding of pleural plaques strongly suggests the diagnosis. The manifestations of bronchogenic carcinoma related to asbestos exposure are varied and do not differ from those unrelated to asbestos exposure. Malignant mesothelioma signals previous asbestos exposure. Nonmalignant pleural disorders may not cause any symptoms but should alert the physician to other concurrent or potential asbestos-related diseases. To diagnose asbestos-related diseases, physicians should bear in mind the long latent period and should take a careful, comprehensive occupational and environmental history. Cigarette smoking markedly increases the risk for development of bronchogenic carcinoma in asbestos workers and increases the mortality due to asbestosis.

1970s

• Asbestos-related diseases of lung and pleura: clinical picture and illustrative cases. B. Varkey, U.N. Kumar. 1978;63(6):48-66. Case report PubMed · Publisher

  Abstract

  Exposure to asbestos may occur in any of a large number of occupations, and the latent period from exposure to appearance of clinical or roentgenologic evidence of related disease of the lung or pleura, or both, may be more than 20 years. A complete occupational history is therefore of paramount importance in the detection of asbestos-related diseases. Illustrative cases highlight the features of benign and malignant diseases of the lung and pleura for which a causal relationship to asbestos exposure is probable or established.

• Industrial lung disease. 1971;50(5):265-8. Case report PubMed · Publisher

Browse every journal in the library or the library by type of article, or return to medical research.