Solitary fibrous tumour of the tongue: a case report with immunohistochemical studies

Our plain-English summary of Solitary fibrous tumour of the tongue: a case report with immunohistochemical studies, by Y. Yamashita, T. Satoh, M. Goto (International Journal of Oral and Maxillofacial Surgery, 2002).

The study

• Authors: Y. Yamashita, T. Satoh, M. Goto
• Journal: International Journal of Oral and Maxillofacial Surgery
• Published: 2002;31(6):681-3
• Type of article: Case report
• Cited by: 20 articles, as counted by NIH iCite
• Read it: PubMed · Publisher

Abstract

The solitary fibrous tumour (SFT), also known as a localized fibrous mesothelioma, is a neoplasm characterized by the proliferation of capillaries surrounded by masses of round or spindle-shaped cells. SFT has been discovered in many locations, however, it is extremely rare for SFT to be found in the intraoral region. We report here case of SFT arising from the tongue of a 75-year-old woman. To our knowledge, this is the second case reported of SFT originating from the tongue.

In plain English

This case report from Saga Medical School in Japan described one patient, a 75-year-old Japanese woman with a tongue tumour that she said had been present for more than 13 years and had recently grown larger. The article describes this tumour type, solitary fibrous tumour, as also known as a localized fibrous mesothelioma. The article does not mention asbestos or any other exposure. A biopsy was first diagnosed as hemangiopericytoma, and the tumour cells were positive for vimentin and CD34. The tumour was then removed through a glossotomy, and no invasion into the muscle was seen. The cells were also positive for bcl-2, and only a small number of MIB1 (Ki-67)-labelled cells were seen. The final diagnosis was solitary fibrous tumour of the tongue. No recurrence had been detected 1 year after removal. The authors believed this was the second reported case of this tumour in the tongue. They concluded that long-term follow-up is necessary even after radical resection, because recurrence or metastasis may be delayed by many years.

We wrote this plain-English summary from the full article with the help of AI, and a second AI model checked each sentence against the article. It is not the authors' wording; the abstract and the article are their own account.

What the study did and found

• Design: case report (single patient)
• Who was studied: One 75-year-old Japanese woman treated at Saga Medical School, Saga, Japan. She reported that the tongue tumour had been present for more than 13 years.
• Main results:
  • In the biopsy specimen, the tumour cells were positive for vimentin and CD34. They were negative for cytokeratin, factor VIII, alpha-smooth muscle actin, S-100 and lysozyme. The biopsy was initially diagnosed as hemangiopericytoma.
  • The tumour was excised through a glossotomy, and no invasion into the muscle was evident.
  • In the surgical specimen, the tumour cells were also bcl-2 positive, and only a small number of MIB1 (Ki-67)-labelled cells were seen. The final diagnosis was solitary fibrous tumour of the tongue.
  • No recurrence was detected 1 year after removal of the tumour.
  • The authors believed this was the second reported case of a solitary fibrous tumour arising from the tongue.
• The authors' conclusion: The authors concluded that long-term follow-up is necessary even after radical resection, because recurrence or metastasis may be delayed by many years.

Topics

Medical terms in this study, explained in our Lexicon: Mesothelioma, Neoplasm, Spindle Cell.

Related studies

• Solitary fibrous tumour of the tongue — A. Piattelli, M. Fioroni, et al. (1998)
• Steroid hormone receptor in pleural solitary fibrous tumours and CD34+ progenitor stromal cells — M. Bongiovanni, L. Viberti, et al. (2002)
• Metastatic pleural mesothelioma presenting with solitary involvement of the tongue: report of a new case and review of the literature — F. Zanconati, A. DelConte, et al. (2003)
• Localized fibrous tumors (LFTs) of the pleura: clinical data, asbestos burden, and syntactic structure analysis applied to newly defined angiogenic/growth-regulatory effectors — K. Kayser, J. Trott, et al. (2005)
• Solitary fibrous tumor of the liver: a clinicopathologic and immunohistochemical study of nine cases — C.A. Moran, K.G. Ishak, et al. (1998)
• Solitary fibrous tumour of the nasal cavity and paranasal sinuses — I. Alobid, L. Alós, et al. (2003)

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