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Manuscript (labeled as a dissertation or book chapter) reporting a morphometric study of lung reactions in male and female Fischer 344 rats exposed by inhalation for 12 months to three aerosolized chrysotiles: UICC B, Jeffrey Mine and Coalinga Mine (identified as COF-25 by Union Carbide). It reports differences in epithelial and interstitial lung reaction, cell numbers, tissue volumes and lung silica content among the three fiber types, and attributes the differences to fiber length and deposition. It includes references, data tables and figures. unreviewed
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- Author
- Kent E. Pinkerton (Departments of Medicine and Pathology, Duke University and Durham V.A. Medical Center); Philip C. Pratt (Departments of Medicine and Pathology, Duke University and Durham V.A. Medical Center); Fred Miller (Environmental Protection Agency, Research Triangle Park, North Carolina); James D. Crapo (Departments of Medicine and Pathology, Duke University and Durham V.A. Medical Center)
- Published by
- Duke University and Durham V.A. Medical Center, Departments of Medicine and Pathology; Environmental Protection Agency, Research Triangle Park
- Series
- Union Carbide documents, UC-1022
- Number
- Bates A17800 to A17847
- Rights
- A published article used as a document in asbestos litigation. Its copyright is not ours, so we describe it and link to it rather than host it.
Read the article
Kent E. Pinkerton, Philip C. Pratt, Fred Miller, James D. Crapo. "LUNG REACTION TO CHRONIC INHALATION OF THREE CHRYSOTILES IN THE FISCHER 344 RAT. I. MORPHOMETRY."
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People and organizations
From Kent E. Pinkerton (Departments of Medicine and Pathology, Duke University and Durham V.A. Medical Center); Philip C. Pratt (Departments of Medicine and Pathology, Duke University and Durham V.A. Medical Center); Fred Miller (Environmental Protection Agency, Research Triangle Park, North Carolina); James D. Crapo (Departments of Medicine and Pathology, Duke University and Durham V.A. Medical Center).
- Frank Miller (author)
- Philip C. Pratt (author)
- EPA (named)
- Johns-Manville (named)
- National Institute of Environmental Health Sciences (named)
- Union Carbide Corporation (named)
- Union Internationale Contre Cancer (named)
Related pages
Pages on our site about what this document covers: Calidria · California Asbestos Exposure Sites: Worksites, Industries, and Trust Coverage · Chrysotile: White Asbestos, the Most Common Type · Coalinga District · EPA · Johns-Manville.
About this copy
This is document UC-1022 of the Union Carbide documents, documents produced and used as evidence in asbestos lawsuits against Union Carbide, 46 pages. Production numbers A17800 to A17847.
Cite this document
Kent E. Pinkerton (Departments of Medicine and Pathology, Duke University and Durham V.A. Medical Center), Philip C. Pratt (Departments of Medicine and Pathology, Duke University and Durham V.A. Medical Center), Fred Miller (Environmental Protection Agency, Research Triangle Park, North Carolina), James D. Crapo (Departments of Medicine and Pathology, Duke University and Durham V.A. Medical Center). “K. E. Pinkerton, P. C. Pratt, F. Miller and J. D. Crapo, Lung Reaction to Chronic Inhalation of Three Chrysotiles (Coalinga, UICC B, Jeffrey) in the Fischer 344 Rat. I. Morphometry.” Union Carbide documents, UC-1022, Bates A17800 to A17847. Duke University and Durham V.A. Medical Center, Departments of Medicine and Pathology; Environmental Protection Agency, Research Triangle Park. AsbestosClaims.Law Library. https://asbestosclaims.law/library/union-carbide-exhibits/uc-1022.
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