7 results for “General Electric”
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Medical study · Medical research · 2008
Malignant mesothelioma 2008
…been studied in recent trials for its effects on disease free and overall survival This review provides a general overview of malignant mesothelioma with a summary of the most significant articles from within the past year…
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Medical study · Medical research · 2015
Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma
This laboratory study read the protein-coding DNA (the 'exome') of tumors from 22 people diagnosed with malignant pleural mesothelioma at the New York University General Thoracic Surgery Service. Each tumor was compared with the same…
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Medical study · Medical research · 2020
Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma
…Therefore, 7 of 155 apparently unrelated mesothelioma patients carried BLM+/- mutations, significantly higher (P = 6.7E-10) than the expected frequency in a general, unrelated population from the gnomAD database, and 2 of 7 carried…
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Medical study · Medical research · 1999
New molecular and epidemiological issues in mesothelioma: role of SV40
…was difficult to draw conclusions. They suggested that SV40 and asbestos might act together. The authors concluded that it would be premature to reach definitive conclusions about SV40's role in mesothelioma in the general population.
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Medical study · Medical research · 2004
Translation research: from accurate diagnosis to appropriate treatment
…relating to the asbestos related cancer mesothelioma, it should be stressed that the general approach outlined throughout this review is readily applicable to other diseases with an underlying molecular basis. Through the integration of molecular-based…
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Medical study · Medical research · 2006
Cross reactivity between many anti-human antibodies for their hamster homologs provide the tools to study the signal transduction pathway activated by asbestos and SV40 in the malignant mesothelioma model
…NFkappaB p65, IkappaB, GAPDH) cross-reacted with their hamster counterparts. These data indicate that hamster mesothelioma model and more in general hamster experimental model, can be used for functional studies because many mouse, rabbit, and goat…
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Medical study · Medical research · 2016
Consensus Report of the 2015 Weinman International Conference on Mesothelioma
…as high mobility group box 1 and fibulin-3, are promising. There was general agreement that current treatment for MM, which is based on surgery and standard chemotherapy, has a modest effect on the overall survival…