124 results for “Reaction Department”, page 3 of 7
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Medical study · Medical research · 1983
Transmigration of ingested asbestos
…with crystals resembling amosite visible inside cells. Saline injected into two control rats caused a smaller reaction. Rats given 100 mg of amosite by stomach tube daily for 5 days showed no macrophage response or other…
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Medical study · Medical research · 1988
Adenomatoid tumour of the uterus
…EMA or CEA. The tumour cells did not stain for Factor VIII, unlike the blood vessels in the same sections. Many tumour cells showed a moderate reaction for keratin, and most, but not all, stained for…
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Medical study · Medical research · 1985
Industrially acquired pulmonary disease
…79% had a smoking history, and none of the smokers stopped after learning of their increased risk. Denial of the danger was the most frequent reaction to risk information. In a later evaluation, 45% of 36…
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Company document · JM Document Review · April 3, 1985
Lois Gaul's Manville Memo on the Bureau of Mines Circular Mineral Wool (1985)
…R. Sayers of the U.S. Public Health Service: mineral-wool fibers produced "an inert foreign body reaction similar to that of asbestos," and the Service had been "considering dust from mineral wool as potentially harmful."
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Medical study · Medical research · 1983
Small-airway lesions in patients exposed to nonasbestos mineral dusts
…which they call mineral dust airways disease, is a nonspecific reaction of the small airways to inorganic particulates. The presence of such changes casts considerable doubt on the theory that small-airway abnormalities in asbestos workers…
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Medical study · Medical research · 1987
Paraplegia due to massive asbestos-related pleural and mediastinal fibrosis
…damage was triggered by reduced blood flow in an already severely compromised circulation. They said they felt the tissue findings represented an unusually florid immune reaction to asbestos. In their view this resembled idiopathic mediastinal fibrosis.
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Medical study · Medical research · 1984
Quantitative x ray microanalysis of pulmonary mineral particles in a patient with pneumoconiosis and two primary lung tumours
…fire clay mineral. The authors concluded the method reliably identified individual particles. They noted it cannot show whether the dust caused the tissue reaction, and that the particles analysed probably did not represent all minerals present.
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Medical study · Medical research · 1987
Response of mouse lung to crocidolite asbestos. 2. Pulmonary fibrosis after long fibres
…These findings suggest that injury to bronchial and bronchiolar epithelium allows long fibres to reach the interstitium where subsequent macrophage-fibroblast interactions result in a severe fibrotic reaction that resembles the bronchiolar component of human asbestosis.
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Medical study · Medical research · 1987
Crocidolite-induced lipid peroxidation in rat lung microsomes. I. Role of different ions
…in rat lung microsomes both from rats pretreated with 3-methylcholanthrene and from untreated controls. This increase was dependent on the concentration of these ions in the reaction mixture. Crocidolite alone increased peroxidation in microsomal fractions…
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Medical study · Medical research · 1983
A murine model of asbestosis
…an initial macrophage reaction was found to progress to "asbestos body" formation and diffuse focal interstitial fibrosis within 1 year of a chronic exposure period. This reaction was most intense in areas adjacent to respiratory bronchioles…
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Medical study · Medical research · 1985
Exogenous particles in lymph nodes in patients with shrinking pleuritis with atelectasis
…pleuritis with atelectasis is a disease in which a compression atelectasis of the lung is caused by shrinking of the inflamed visceral pleura. This reaction has been attributed to asbestos. By means of scanning electron microscopy…
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Medical study · Medical research · 1986
Distinct keratin patterns demonstrated by immunoperoxidase staining of adenocarcinomas, carcinoids, and mesotheliomas using polyclonal and monoclonal anti-keratin antibodies
…10 adenocarcinomas, 10 carcinoids, and 4 mesotheliomas by an immunoperoxidase reaction using 3 polyclonal and 3 monoclonal antibodies to keratin. When color development in diaminobenzidine (DAB) was allowed to proceed for less than 2 minutes, distinct…
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Medical study · Medical research · 1986
Alveolar macrophage stimulation of lung fibroblast growth in asbestos-induced pulmonary fibrosis
…proliferation, and collagen deposition. To evaluate the potential involvement of alveolar macrophages in the subsequent fibrogenic reaction, the authors studied the effects of macrophages from normal and asbestos-treated rats upon lung fibroblast proliferation in vitro…
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Medical study · Medical research · 1983
Diseases associated with asbestos exposure. Diagnostic perspectives in forensic pathology
…and its numerous applications. Its biological effects, which include fibrogenesis and carcinogenesis, may be related to the cellular reaction, to its large specific surface, or to the size and shape of the fibers. Its oncogenic action…
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Medical study · Medical research · 1988
Railroad workers with pleural plaques: II. Small airway dysfunction among asbestos-exposed workers
…groups the VTG:TLC ratio was elevated compared with controls. Increased VTG is a sign of small airways dysfunction. In asbestos-exposed subjects, it might be caused by an early peribronchial reaction to inhaled asbestos fibers.
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Medical study · Medical research · 1983
Effects of chrysotile on a lysosomal enzyme preparation and on the hydrolytic enzyme activity of cultured alveolar macrophages
…inhibit or enhance lysosomal enzyme activity at either pH but may preferentially absorb specific enzymes and that the binding reaction between any given enzyme and mineral can be dependent on the presence of other organic compounds…
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Medical study · Medical research · 1985
Immunohistochemical staining for vimentin and keratin in malignant mesothelioma
…were negative. In the mesotheliomas that did stain, both epithelial and spindled elements gave a positive reaction. Three alcohol-fixed lung cancers and two blocks of alcohol-fixed pleura failed to stain for vimentin. By contrast…
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Medical study · Medical research · 1981
Diminished suppressor cell function in patients with asbestosis
…patients. Skin reaction to dinitrochlorobenzene (DNCB) was not depressed, although lymphocytes of patients giving positive skin test reactions demonstrated a significantly lower (P less than 0.001) proliferative response to dinitrobenzene sulphonic acid (DNBSO3) in vitro…
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Medical study · Medical research · 1986
Studies on surface properties of asbestos. II. Role of dimensional characteristics and surface properties of mineral fibers in the induction of pleural tumors
…mineral and therefore the nature of active surface sites, and the aspect ratio of the particle. These two parameters can intervene in a mechanism of model reaction involving the basic properties of lateral faces of fibers.
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Medical study · Medical research · 1983
Method for removing the ferruginous coating from asbestos bodies
…treatment consisted of an 8% oxalic acid bath used at various temperatures. It was determined that at 75 degrees C the reaction resulted in removal of the ferruginous coat, leaving an exposed core for further analysis…