124 results for “Reaction Department”, page 2 of 7
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Medical study · Medical research · 2006
Biocatalytic ammonolysis of (5S)-4,5-dihydro-1H-pyrrole-1,5-dicarboxylic acid, 1-(1,1-dimethylethyl)-5-ethyl ester: preparation of an intermediate to the dipeptidyl peptidase IV inhibitor Saxagliptin
…temperatures, and amounts of enzyme and ammonium carbamate. Adding calcium chloride raised the amide yield to 79%. Placing Ascarite above the reaction mixture, where it was presumed to absorb carbon dioxide, raised the yield to 95%…
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Medical study · Medical research · 2004
Re: Controlled use of asbestos
…which were not published, reported fibrotic lesions or lung damage; in 1966 the Coalinga sample produced the most severe reaction. The authors stated that UCC consultants misrepresented Pinkerton's data. Their review of King City mine…
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Medical study · Medical research · 2003
Ascorbic acid modifies the surface of asbestos: possible implications in the molecular mechanisms of toxicity
…consequence of the erosion of the outmost layers while hydration of silica tetrahedra yields new silanol groups. The activity in the Fenton-like reaction (OH from H(2)O(2)) decreases following surface iron depauperation. Conversely…
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Medical study · Medical research · 2008
Detection of chrysotile asbestos by using a chrysotile-binding protein
…m' elsewhere. In rockwool mixed with chrysotile, the bound protein was released from the washed sample and then reacted: a one-minute color reaction detected 1% chrysotile, and a 30-minute incubation detected 0.1%. The…
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Medical study · Medical research · 2001
Free radical generation in the toxicity of inhaled mineral particles: the role of iron speciation at the surface of asbestos and silica
…1.3 to 29 nmol/mg. It also increased one radical reaction, breaking a carbon-hydrogen bond, about 3-fold, while heating in air fully stopped that reaction. The other reaction, hydroxyl radical release from hydrogen…
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Medical study · Medical research · 2000
Phospholipase A2-mediated superoxide production of murine peritoneal macrophages induced by chrysotile stimulation
…induced O(2) production, and (2) two different kinds of PLA(2) work upstream and downstream of PKC, but (3) G-protein, 5-LO and COX metabolites, and PAF have no modulatory role in the reaction.
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Medical study · Medical research · 2009
Multiwalled carbon nanotube buckypaper: toxicology and biological effects in vitro and in vivo
…BP induced a moderate inflammatory reaction but had no mutagenic effects. After BP implantation the animals showed an inflammatory reaction followed 2 weeks later by a cicatrization reaction with the organization and fibrosis of the scar…
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Medical study · Medical research · 2001
Sarcomatous mesothelioma in the left ventricle: a rare entity
…damaging the valve. Microscopic and immunohistochemical tests confirmed a sarcomatous (fibrous) mesothelioma, with a positive reaction to HBME-1. The patient recovered without complications and left hospital on the ninth day after surgery. At 3 months…
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Medical study · Medical research · 2001
Cutaneous toxicity after intradermal vaccination with Mycobacterium vaccae against lung cancer and malignant mesothelioma
This letter reported two patients at the Royal Marsden Hospital who developed unusual skin reactions after injections into the skin of SRL172, a heat-killed Mycobacterium vaccae vaccine being tested against cancer. The first, a 52…
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Medical study · Medical research · 2003
Regression of AK7 malignant mesothelioma established in immunocompetent mice following intratumoral gene transfer of interferon gamma
…10% with a control virus. The authors concluded that local interferon gamma had antitumor activity in this model. They noted that the immune reaction was not enough to produce an efficient memory response, since tumors relapsed.
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Medical study · Medical research · 2009
The thermal transformation of Man Made Vitreous Fibers (MMVF) and safe recycling as secondary raw materials (SRM)
…wt.% of the melts of Rock and Glass wool gave promising results in terms of viscous sintering reactions and resistance to staining with the only weak characteristic being the color properties of the fired bodies which…
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Medical study · Medical research · 2000
Epithelial mesothelioma with deciduoid features: report of four cases
Deciduoid mesothelioma is the designation given to an unusual morphologic variant of epithelial mesothelioma that closely simulates exuberant ectopic decidual reaction. Because all four previously reported cases involved the peritoneum and occurred in young women without…
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Medical study · Medical research · 2008
Magnesium hydroxide extracted from a magnesium-rich mineral for CO2 sequestration in a gas-solid system
Magnesium hydroxide extracted from magnesium-bearing minerals is considered a promising agent for binding CO2 as a carbonate mineral in a gas-solid reaction. An efficient extraction route consisting of hydrothermal treatment on serpentine in HCl…
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Medical study · Medical research · 2001
Absence of SV-40 large T antigen (Tag) in malignant mesothelioma effusions: an immunocytochemical study
…a function of a nuclear protein, the large T antigen (Tag). SV-40 Tag DNA sequences are detected by the polymerase chain reaction in 40-80% of malignant mesothelial proliferations. However, the role of immunohistochemistry (IHC…
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Medical study · Medical research · 2000
Simian virus (SV) 40 like sequences in cell lines and tumour biopsies from Australian malignant mesotheliomas
…its gene products in tissue derived from mesotheliomas would detract from this possibility. We used polymerase chain reaction from three pairs of primers to amplify different regions of the large T antigen from DNA from cell…
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Medical study · Medical research · 2002
The presence of simian-virus 40 sequences in mesothelioma and mesothelial cells is associated with high levels of vascular endothelial growth factor
…detected in conditioned media of each of two MM cells that tested positive for SV40 by PCR amplification and Southern blot hybridization and for Tag transcript by reverse transcription- polymerase chain reaction (RT-PCR) and immunoprecipitation…
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Medical study · Medical research · 2001
Endothelial nitric oxide synthase is strongly expressed in malignant mesothelioma but does not associate with vascular density or the expression of VEGF, FLK1 or FLT1
…Two mesothelioma (M14K, M38K) and one non-neoplastic mesothelial cell line (MET-5A) were studied for eNOS mRNA expression by reverse transcriptase-polymerase chain reaction (RT-PCR). Vascular density was determined by staining the samples with…
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Medical study · Medical research · 2003
Expression of Clara cell secretory protein in the lungs of rats exposed to silicon carbide whisker in vivo
…1 month, 3 months and 6 months of recovery time. The expression of CCSP was observed by reverse transcriptase-polymerase chain reaction (RT-PCR), Western blot and immunostaining. Exposure to 10 mg of SiCW decreased in…
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Medical study · Medical research · 2009
Association of transforming growth factor beta1 gene polymorphisms and asbestos-induced fibrosis and tumors
…Therefore, we examined an association between the 2 TGF-beta1 gene polymorphisms and asbestos-induced lung fibrosis and lung cancer. Detection of the 2 polymorphisms was performed by rapid capillary polymerase chain reaction, with melting curve…
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Medical study · Medical research · 2004
The pathology associated with therapeutic procedures in malignant mesothelioma
…biphasic pattern to the neoplasm. In more chronic cases, paucicellular fibrosis with a foreign body giant cell reaction is noted. The talc is polarizable and deposited in linear fashion within the tumour. In 2/28 (7…