Adenomatoid tumor of ejaculatory duct

Our plain-English summary of Adenomatoid tumor of ejaculatory duct, by K. Fan, D.F. Johnson (Urology, 1985).

The study

• Authors: K. Fan, D.F. Johnson
• Journal: Urology
• Published: 1985;25(6):653-4
• Type of article: Case report
• Cited by: 9 articles, as counted by NIH iCite
• Read it: PubMed · Publisher

Abstract

Adenomatoid tumors are generally restricted to the epididymal region and occasionally the spermatic cord in the male. Herein we report on a case of adenomatoid tumor apparently originating from the ejaculatory duct which to our knowledge has not been reported previously.

In plain English

This article was a case report from the Veterans Administration Medical Center in Little Rock, Arkansas. It described a 68-year-old white man with recurrent chronic cystitis and acute hemorrhagic cystitis who had his bladder and prostate surgically removed. Examination of the removed tissue found a 0.4-cm whitish nodule at the proximal ejaculatory duct. Under the microscope, the nodule was a tumor that appeared continuous with the ejaculatory duct. It did not stain for two prostate markers, prostate specific antigen and prostate specific acid phosphatase. It showed no reaction for factor VIII antigen. It contained faint focal mucin and some yellowish brown pigment. The authors separated it from a papillary adenoma of the seminal vesicle based on features including hyalinized stroma and mixed epithelial and endothelial-like lining cells. The authors stated that the tumor apparently originated from the ejaculatory duct, which to their knowledge had not been reported. They concluded that adenomatoid tumor can occur in the ejaculatory duct. The article does not mention asbestos or any exposure.

We wrote this plain-English summary from the full article with the help of AI, and a second AI model checked each sentence against the article. It is not the authors' wording; the abstract and the article are their own account.

What the study did and found

• Design: case report of a single patient
• Who was studied: one 68-year-old white man treated at the Veterans Administration Medical Center, Little Rock, Arkansas, who had a total cystectomy including prostatectomy for recurrent chronic and acute hemorrhagic cystitis
• Main results:
  • Gross examination of the surgical specimens found a 0.4-cm whitish nodular lesion at the proximal ejaculatory duct
  • Under the microscope, the tumor appeared continuous with the ejaculatory duct
  • The tumor did not stain for prostate specific antigen or prostate specific acid phosphatase, while the prostatic tissue stained strongly positive
  • The tumor was negative for factor VIII antigen on immunoperoxidase staining
  • Focal faint mucin was seen with mucicarmine staining
  • The tumor occasionally contained yellowish brown pigment
  • The authors distinguished the tumor from a papillary adenoma of the seminal vesicle based on hyalinized stroma, mixed epithelial and endothelial-like lining cells, and lack of papillary configuration
  • The authors described the tumor as apparently originating from the ejaculatory duct, which to their knowledge had not been reported previously
• The authors' conclusion: The authors concluded that they had submitted evidence indicating that adenomatoid tumor can occur in the ejaculatory duct

Topics

The National Library of Medicine indexes this study under subjects our site covers: Mesothelioma.

Medical terms in this study, explained in our Lexicon: Adenomatoid Tumor, Spermatic Cord.

Related studies

• Adenomatoid tumors of the male and female genital tract are defined by TRAF7 mutations that drive aberrant NF-kB pathway activation — B. Goode, N.M. Joseph, et al. (2018)
• Sonography of intrascrotal adenomatoid tumor — W.C. Leonhardt, G.A. Gooding (1992)
• Absence of estrogen immunoreactivity in adenomatoid tumors of male reproductive system — J.I. Lopez, F.I. Aranda (1990)
• Adenomatoid tumour of the epididymis: histochemical and ultrastructural study of 2 cases — M. Nistal, F. Contreras, et al. (1978)
• Treatment of malignant tumors of the spermatic cord: a study of 10 cases and a review of the literature — P.H. Blitzer, D.E. Dosoretz, et al. (1981)
• Paratesticular tumors. A clinicopathological study from a single tertiary hospital in North India — P.A.M. Paul, N. Calton, et al. (2021)

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