Urology

Our medical research library holds 16 studies published in Urology (1974–2018). Each entry links to the study's record on PubMed and, where there is one, to the publisher's page and a free full text. 13 have an abstract, the authors' own summary as PubMed records it: open "Abstract" to read it. For 2 studies PubMed has no abstract for, we give the abstract printed in the article or, where there is none, a summary we wrote from it, each labeled as such.

About the journal

• Publisher: Elsevier Science
• Published: 1973 to the present, United States
• Language: English
• ISSN: 0090-4295 (print), 1527-9995 (electronic)
• Its record in the NLM Catalog

2010s

• A Bilateral Metachronous Mesothelioma of the Tunica Vaginalis. A. Abello, J. Steinkeler, A.K. Das. 2018;120:e1-e2. PubMed · Publisher

  Abstract

  This is a unique case of bilateral metachronous testicular mesothelioma of the tunica vaginalis. Testicular mesothelioma is a rare entity found in patients with or without asbestos occupational exposure. The tumor most commonly presents as a unilateral testicular mass. More rare presentations include bilateral synchronous or metachronous tumors. Treatment is with surgical resection and prognosis is not generally favorable. The benefits of adjuvant therapy with radiation or chemotherapy remain unknown and further studies are needed.

  Copyright © 2018 Elsevier Inc. All rights reserved.

• Malignant Mesothelioma of the Tunica Vaginalis Testis: Outcomes Following Surgical Management Beyond Radical Orchiectomy. P. Recabal, B. Rosenzweig, W.M. Bazzi, et al. 2017;107:166-170. PubMed · Publisher · Free full text

  Abstract

  Objective: To describe clinical management and outcomes of a cohort of patients with malignant mesothelioma of the tunica vaginalis testis (MMTVT) who received treatments beyond radical orchiectomy.

  Methods: Patients with confirmed MMTVT at a single tertiary care institution were identified. Treatments, pathologic outcomes, and survival were recorded. Prognostic variables associated with survival were analyzed with a Cox proportional hazards model and Kaplan-Meier curves.

  Results: Overall, 15 patients were included. Initial presentation was a scrotal mass in 7 of 15 (47%) and hydrocele in 5 of 15 (33%) patients. Clinical staging revealed enlarged nodes in 5 of 15 (33%) patients. Radical orchiectomy was the initial treatment in 5 of 15 (33%) patients. Positive surgical margins were found in 6 of 14 (43%) radical orchiectomies and were associated with worse survival (P = .007). The most frequent histologic subtype was epithelioid, associated with better survival (P = .048). Additional surgeries were performed on 12 of 15 (80%) patients. Pathologic examination revealed MMTVT in 6 of 12 (50%) hemiscrotectomies, 7 of 8 (88%) retroperitoneal lymph node dissections, 1 of 7 (14%) pelvic lymph node dissections, and 10 of 10 (100%) groin dissections. Five patients received adjuvant chemotherapy. Two also received adjuvant radiation therapy. Three patients with lymph node involvement remain no evidence of disease over 6 years after diagnosis. After a median follow-up of 3.5 years (interquartile range: 1.2-7.2), 5 patients have died, all of MMTVT; the median overall survival has not been reached. Common sites of relapse were lungs (5 of 7) and groin (3 of 7).

  Conclusion: The pattern of metastatic spread of MMTVT is predominantly lymphatic. Nodes in the retroperitoneum and the groin are commonly involved. Prognosis is poor, but there may be a role for aggressive surgical resection including hemiscrotectomy, and inguinal and retroperitoneal lymph nodes.

  Copyright © 2017 Elsevier Inc. All rights reserved.

• Malignant Mesothelioma of Spermatic Cord in an Elderly Man With a History of Asbestos Exposure. A. D'Antonio, F. Mastella, A. Colucci, et al. 2016;87:e1-3. Case report PubMed · Publisher

  Abstract

  We report a case of malignant mesothelioma of the spermatic cord in 80-year-old man presented with retained testis, hydrocele, and right inguinal mass. The patient had a long history of asbestos exposure as a railway worker. The patient was submitted to inguinal radical orchiectomy. One year after surgery, the patient is alive without signs of disease. Malignant mesothelioma of spermatic cord is a very rare disease, but this diagnosis should be suspected in patient with a history of asbestos exposure.

  Copyright © 2015 Elsevier Inc. All rights reserved.

• Well-differentiated Papillary Mesothelioma of the Tunica Vaginalis. W.K. Tan, M.Y. Tan, H.M. Tan, et al. 2016;90:e7-8. Case report PubMed · Publisher

  Abstract

  A 39-year-old man presented with painless scrotal swelling for 2 months. He denied any asbestos exposure but worked with wall and ceiling plaster. Physical exam revealed a large right scrotum which transilluminated. Scrotal ultrasonography revealed a large right hydrocele and a polypoidal mass along the anterior wall of the scrotum. Magnetic resonance imaging of the abdomen and computed tomography of the chest showed no metastases. He underwent a right inguinal scrotal exploration and wide excision of tunica vaginalis and a partial epididymectomy. Pathology revealed well-differentiated papillary mesothelioma of the tunica vaginalis. The patient had an uneventful recovery.

  Copyright © 2016 Elsevier Inc. All rights reserved.

• Radiologic findings of mesothelioma at the tunica vaginalis. S.W. Doo, K.H. Cho, J.S. Kim, et al. 2012;80(1):e3-5. Case report PubMed · Publisher

  Abstract

  Malignant mesothelioma of the tunica vaginalis testis is a rare, but often fatal, malignancy that usually appears during the fourth decade and has a strong relationship with occupational exposure to asbestos and long-lasting hydrocele. We present a case involving a 36-year-old man without a history of hydrocele, trauma, or exposure to asbestos who developed malignant mesothelioma.

  Copyright © 2012 Elsevier Inc. All rights reserved.

• Preoperative diagnosis of malignant mesothelioma of the tunica vaginalis using Doppler ultrasound. P. Aggarwal, A. Sidana, S. Mustafa, et al. 2010;75(2):251-2. Case report PubMed · Publisher

  Abstract

  Malignant mesothelioma (MM) of the tunica vaginalis is a rare aggressive tumor with a high predilection for metastatic spread. Because there is no preoperative diagnostic modality available, it has high recurrence and mortality rates, which emphasizes the importance of early preoperative diagnosis for proper and adequate treatment. We describe a case of MM of the tunica vaginalis in a 73-year-old man who presented with hydrocele and was preoperatively diagnosed with MM using Doppler in addition to scrotal ultrasound. He underwent early radical orchiectomy through an inguinal approach, resulting in improved survival.

  2010 Elsevier Inc. All rights reserved.

2000s

• Malignant mesothelioma of the tunica vaginalis. P.E. Spiess, T. Tuziak, W. Kassouf, et al. 2005;66(2):397-401. PubMed · Publisher

  Abstract

  Objectives: To review our experience with the management of malignant mesothelioma of the tunica vaginalis with emphasis on disease-related outcomes.

  Methods: A retrospective chart review of patients seen during the past 25 years at our cancer center identified 5 cases of malignant mesothelioma of the tunica vaginalis.

  Results: The mean age of patients at presentation was 61.2 years (range 57 to 83). Asbestos exposure was identified in 4 patients. Three patients presented with clinical symptoms suggestive of a hydrocele and two presented with clinical signs of an inguinal hernia. The final diagnosis was established intraoperatively in 1 patient and postoperatively in the remaining 4. Radical orchiectomy or hernia sac with spermatic cord excision was the primary treatment modality. Although radical surgical treatment achieved negative resection margins in 4 cases, 4 of 5 patients died of the disease, with a mean disease-specific survival of only 29 months (range 5 to 68). Regional inguinal lymph node metastasis developed in 3 of 5 patients. Salvage therapy did not prove curative in the 2 patients who received it.

  Conclusions: Malignant mesothelioma of the tunica vaginalis constitutes a rare but often fatal malignancy of the male genitalia. This diagnosis should be suspected in patients exposed to asbestos and presenting with clinical symptoms of either hydrocele or inguinal hernia. Frequent inguinal lymph node involvement indicates a potential role of inguinal lymphadenectomy in the primary treatment.

1990s

• Sonography of intrascrotal adenomatoid tumor. W.C. Leonhardt, G.A. Gooding. 1992;39(1):90-2. Case report · Review PubMed · Publisher

  Abstract

  A case is reported of an adenomatoid tumor of the epididymis. A discussion of the appropriate differential of mass of the epididymis as well as a review of adenomatoid tumors per se and their occurrence in the scrotum are presented.

1980s

• Malignant mesothelioma of tunica vaginalis testis. G. Tyagi, C.S. Munn, L.C. Kiser, et al. 1989;34(2):102-4. Case report PubMed · Publisher

  Abstract

  Malignant mesothelioma of the tunica vaginalis is rare, but sometimes curable. It is similar to malignant mesothelioma of the peritoneum and of the pleura, and is likewise associated with asbestos exposure. We report a case, with correlative computed tomography, ultrasound, and gross pathology images that demonstrate tiny tumor implants studding the vaginalis testis. The literature is reviewed.

• Adenomatoid tumor of ejaculatory duct. K. Fan, D.F. Johnson. 1985;25(6):653-4. Case report PubMed · Publisher

  Abstract

  Adenomatoid tumors are generally restricted to the epididymal region and occasionally the spermatic cord in the male. Herein we report on a case of adenomatoid tumor apparently originating from the ejaculatory duct which to our knowledge has not been reported previously.

• Adenomatoid prostatic tumor. K.T. Chen, J.J. Schiff. 1983;21(1):88-9. Case report PubMed · Publisher

  Abstract

  A prostatic tumor is presented that histologically resembles adenomatoid tumor arising in other sites. The intraprostatic location and positive prostatic acid phosphatase immunoperoxidase staining support prostatic epithelial origin of the tumor. This study further confirms the histogenetic heterogeneity of the adenomatoid tumor.

  PubMed has no abstract for this study. This is the authors' abstract, copied from the article.

• Malignant mesothelioma of tunica vaginalis testis. K.T. Chen, R.B. Arhelger, M.S. Flam, et al. 1982;20(3):316-9. Case report PubMed · Publisher

  Abstract

  A case of biphasic malignant mesothelioma of the tunica vaginalis occurring in a sixty-four-year-old man is described. The tumor metastasized widely and led to the patient's death two and one-half years after diagnosis. Review of the literature revealed 7 cases of malignant mesothelioma of tunica vaginalis. These tumors appeared highly aggressive with early onset of metastasis. Histologically, the tumors may be epithelial, fibrous, or biphasic. In contrast to the benign variants of mesotheliomas, these tumors often show significant nuclear atypia, mitotic activity, and invasion of the epididymis, spermatic cord, lymphatic spaces, or the fibrous tissue of the tunica.

• Nephrogenic adenoma of bladder. S.I. Tannenbaum, S.A. Kramer, W.H. Gibson, et al. 1980;15(5):518-9. Case report PubMed · Publisher

  In plain English

  This 1980 article is a case report about one patient with nephrogenic adenoma, a rare bladder tumor, followed by a short review of that tumor. The article does not mention asbestos. The patient was a 72-year-old Black man referred for a narrowing of the urethra (urethral stricture) and twelve months of bladder irritation symptoms. The article states he had no history of exposure to urinary carcinogens. His urine contained 25 red blood cells and 10 white blood cells per high-powered field, and a urine culture was negative. A scope examination of the bladder found a 0.5-cm superficial, red, papillary (finger-like) growth on the right side wall of the bladder. The growth was removed through the urethra. Under the microscope, the tumor contained structures resembling kidney tubules. There was no evidence that it had invaded muscle or blood vessels. Urine cell tests and scope examinations twelve months later were negative. The authors concluded that nephrogenic adenoma in the bladder reflects the ability of the bladder lining to change into other tissue types (its metaplastic potential).

  We wrote this plain-English summary from the full article with the help of AI, and a second AI model checked each sentence against the article. It is not the authors' wording; the abstract and the article are their own account.

1970s

• Mesothelioma of spermatic cord: electron microscopic and histochemical characteristics of its mucopolysaccharides. P. Pizzolato, J. Lamberty. 1976;8(4):403-8. Case report PubMed · Publisher

  Abstract

  A mesothelioma of the spermatic cord occurred at the site of multiple hernial repairs. The aggressive biologic behavior of this tumor is exhibited by its early lymph node invasion and extensive metastases to the pleural cavities, lungs, and spleen. These tumor cells contained a large amount of stable of stable glycogen-like carbohydrate insoluble in formalin and tolerating postmortem changes. Electron microscopy revealed features similar to those mesotheliomas arising from body cavities.

• Nephrogenic metaplasia (adenomatoid tumors) of bladder. J.A. Kaswick, J. Waisman, W.E. Goodwin. 1976;8(3):283-6. Case report PubMed · Publisher

  Abstract

  Two cases of rare nephrogenic metaplasia of the bladder (adenomatoid bladder tumor) support the theory that these tumors originate as an atypical metaplastic response of urothelium to chronic infection or irritation. That these may also represent mesonephric or mesothelial choristomas is considered. Although benign, they may recur. Therapy should consist of antibiotics and transurethral resection or fulguration.

• Nephrogenic adenoma of bladder. E. Kaany, S.L. Werner. 1974;4(3):343-5. PubMed · Publisher

  Abstract

  An unusual case of nephrogenic adenoma of the bladder is presented, with a review of the current literature. The association of previous bladder trauma and chronic infection of the bladder is emphasized.

  PubMed has no abstract for this study. This is the authors' abstract, copied from the article.

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