Nephrogenic adenoma of bladder

Our plain-English summary of Nephrogenic adenoma of bladder, by S.I. Tannenbaum, S.A. Kramer, W.H. Gibson, et al (Urology, 1980).

The study

• Authors: S.I. Tannenbaum, S.A. Kramer, W.H. Gibson, C.C. Carson
• Journal: Urology
• Published: 1980;15(5):518-9
• Type of article: Case report
• Cited by: 19 articles, as counted by NIH iCite
• Read it: PubMed · Publisher

In plain English

This 1980 article is a case report about one patient with nephrogenic adenoma, a rare bladder tumor, followed by a short review of that tumor. The article does not mention asbestos. The patient was a 72-year-old Black man referred for a narrowing of the urethra (urethral stricture) and twelve months of bladder irritation symptoms. The article states he had no history of exposure to urinary carcinogens. His urine contained 25 red blood cells and 10 white blood cells per high-powered field, and a urine culture was negative. A scope examination of the bladder found a 0.5-cm superficial, red, papillary (finger-like) growth on the right side wall of the bladder. The growth was removed through the urethra. Under the microscope, the tumor contained structures resembling kidney tubules. There was no evidence that it had invaded muscle or blood vessels. Urine cell tests and scope examinations twelve months later were negative. The authors concluded that nephrogenic adenoma in the bladder reflects the ability of the bladder lining to change into other tissue types (its metaplastic potential).

We wrote this plain-English summary from the full article with the help of AI, and a second AI model checked each sentence against the article. It is not the authors' wording; the abstract and the article are their own account.

What the study did and found

• Design: case report with a brief review of the tumor's embryology, histopathology and treatment
• Who was studied: one 72-year-old Black man with urethral stricture and a twelve-month history of bladder irritative symptoms
• Exposure: No asbestos or other fiber exposure is discussed. The article states the patient had no history of exposure to urinary carcinogens.
• Main results:
  • The patient's urinalysis showed 25 red blood cells and 10 white blood cells per high-powered field. His urine culture was negative.
  • Cystourethroscopy found a 0.5-cm superficial, erythematous, papillary lesion on the right lateral bladder wall.
  • On microscopic examination, structures resembling renal tubular elements were present within the tumor's stroma (supporting tissue).
  • There was no evidence of muscular or vascular invasion by the tumor.
  • The tumor was removed by transurethral resection. Follow-up urine cytology and cystourethroscopy at twelve months were negative.
• The authors' conclusion: The authors concluded that the occurrence of nephrogenic adenoma in the bladder reflects the metaplastic potential of the bladder lining (urothelium) to differentiate.

Topics

The National Library of Medicine indexes this study under subjects our site covers: Mesothelioma.

Related studies

• Nephrogenic adenoma: a form of adenomatous metaplasia of the bladder. A clinical and electron microscopical study — E.A. Molland, P.A. Trott, et al. (1976)
• Nephrogenic adenoma of bladder — E. Kaany, S.L. Werner (1974)
• Nephrogenic adenoma of the bladder in children — S.R. Nold, W.J. Terry, et al. (1989)
• Nephrogenic metaplasia (adenomatoid tumors) of bladder — J.A. Kaswick, J. Waisman, et al. (1976)
• Nephrogenic metaplasia of the bladder — E.B. Sussman, M. Brice, et al. (1974)
• Use of job-exposure matrix in an occupational analysis of lung and bladder cancers on the basis of death certificates — D. Coggon, B. Pannett, et al. (1984)

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