Medical and Pediatric Oncology

Our medical research library holds 8 studies published in Medical and Pediatric Oncology (1978–1998). Each entry links to the study's record on PubMed and, where there is one, to the publisher's page and a free full text. 6 have an abstract, the authors' own summary as PubMed records it: open "Abstract" to read it.

About the journal

• Publisher: Wiley-Liss
• Published: 1975–2003, United States
• Language: English
• ISSN: 0098-1532 (print), 1096-911X (electronic)
• Continued by: Pediatric Blood & Cancer
• Its record in the NLM Catalog

1990s

• Long-term follow-up of a well-differentiated mesothelioma of the peritoneum in a 2-year-old girl. L. Wünsch, P. Flemming, A. Reiter. 1998;31(2):123-4. Case report PubMed · Publisher

• Nonlymphoid gastrointestinal malignancies in Turkish children. M. Büyükpamukçu, S. Berberoğlu, N. Büyükpamukçu, et al. 1996;26(1):28-35. PubMed · Publisher

  Abstract

  Nonlymphoid gastrointestinal malignancies are not frequently encountered malignant tumors of childhood. From 1972 to 1994, at Hacettepe University Children's Hospital, there were 6,774 malignant tumors encountered in patients from birth to age 17. Thirty-five of them (0.5%) originated from the gastrointestinal tract. There were five carcinoid tumors, four pancreas tumors (two were solid-cystic tumors), four APUD-omas, three leiomyosarcomas, one mesothelioma, two carcinomas of the stomach and duodenum, and 16 colon and rectum carcinomas (12 were mucin-producing). These rare tumors are discussed according to the characteristics of the patients, therapy modalities applied, and outcome of the patients.

• Cardiac tamponade as the initial manifestation of primary pericardial mesothelioma. M. Stein, A. Neuman, J. Dale, et al. 1995;24(3):208-12. Case report PubMed · Publisher

  Abstract

  Although cardiac tamponade is a known complication of malignancy, it is rarely the initial manifestation. We report a 46-year-old male who presented with malignant cardiac tamponade 6 months prior to the definitive diagnosis of primary pericardial mesothelioma. A thorough literature search has not revealed a similar care.

• Hypertrophic osteoarthropathy in childhood malignancy. C.R. Staalman, U. Umans. 1993;21(9):676-9. Case report · Review PubMed · Publisher

  Abstract

  Hypertrophic osteoarthropathy (HOA), well known in adults, is rarely encountered in children. The clinical features include clubbing of the fingers and toes, arthritis, and a sometimes painful ossifying periostitis of the tubular bones. Apart from a hereditary form (primary HOA), most of the cases encountered in children are secondary and associated with conditions such as chronic suppurative lung processes (e.g., cystic fibrosis), congenital heart disease, biliary atresia, and polyposis coli. The association with malignant disorders, which is relatively common in adults, is very rare in children. In 1986 the authors published a case report of a patient with carcinoma of the nasopharynx who developed HOA. Another similar patient has been encountered. In both, the appearance of HOA was associated with a very poor prognosis. A meticulous research of the literature from 1890 to 1990 revealed only 24 children (19 boys, 5 girls) under the age of 18, with malignancy and associated HOA. Among them were 10 patients with a carcinoma of the nasopharynx, 8 with osteosarcoma, 3 with Hodgkin's lymphoma, 1 with a periosteal sarcoma, 1 with mesothelioma of the pleura, and 1 with carcinoma of the thymus. In five patients with HOA, there were no abnormalities of the lungs, mediastinum, or pleura, and none developed during the course of the disease. Many authors mention the predictive value of HOA, especially in association with malignant tumors. In contrast to suppurative processes in the lungs, in those with neoplastic disease involving the chest, HOA may precede pulmonary symptoms by 1-18 months. A striking feature of HOA in these instances is the reversibility of the complaints after successful treatment of the disorder of the chest, both in benign and malignant conditions. The present case is the second reported by the authors and the first description of a girl with carcinoma of the nasopharynx developing HOA.

• Bone metastases in malignant mesothelioma are not uncommon. A. Dejmek. 1992;20(1):86. Comment · Letter PubMed · Publisher

• Malignant mesothelioma with bone metastases. W.F. Cheng, A.W. Berkman. 1990;18(2):165-8. Case report · Review PubMed · Publisher

  Abstract

  Malignant mesothelioma has rarely been reported to metastasize to bone. This is a report of a 71-year-old man who presented with pleural mesothelioma. After a course of chemotherapy, the patient developed lower back pain. Plain X-ray and bone scan were negative for metastases, but magnetic resonance imaging (MRI) revealed multiple metastatic lesions to the thoracolumbar vertebrae. Subsequent lumbar spine biopsy confirmed the presence of malignant mesothelioma. The patient then received radiation therapy. This report illustrates an unusual presentation for malignant mesothelioma and shows that, in addition, when bone metastases are clinically suspected, MRI may be a useful adjunct to more conventional imaging approach.

1980s

• Malignant mesothelioma in children: report of seven cases and review of the literature. J. Brenner, P.P. Sordillo, G.B. Magill. 1981;9(4):367-73. Case report · Review PubMed · Publisher

  Abstract

  Seven children with malignant mesothelioma have been seen at Memorial Hospital since 1953. In six, the origin was at the pleura and in one at the peritoneum. None of the patients related a history of exposure to asbestos. Two patients lived more than five years. The other five patients died within two years of the diagnosis. Distant metastases were seen in four of the patients, including three who had metastases to brain. Surgery or radiotherapy were not effective in controlling the disease in most of the patients. One patient had a complete response to a combination of Adriamycin, cyclophosphamide, and vincristine and has remained free of disease for 5 1/2 years. The seven cases are reviewed, as are the other 42 cases of malignant mesothelioma in children reported in the literature.

1970s

• Plasmacytomas and mesothelioma. M.C. Perry, A. Solinger, M. Farhangi, et al. 1978;5(1):205-12. Case report PubMed · Publisher

  Abstract

  A patient is reported who developed five plasmacytomas over a four-year period and developed a pleural mesothelioma 12 years later. The relationship of these two entities is discussed and the question of a common environmental carcinogen is raised.

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