1,074 results for “Reaction Department”, page 15 of 54
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Medical study · Medical research · 1982
"Labrador lung": an unusual mixed dust pneumoconiosis
…ferruginous bodies; one ferruginous body was identified as having a core of anthophyllite. A granulomatous reaction was seen in two biopsy specimens and typical silicotic nodules were found in two others. The relatively brief exposure, especially…
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Medical study · Medical research · 2010
Administration of cisplatin in three patients with carboplatin hypersensitivity: is skin testing useful?
…of treatment. The aim of this study was to determine the usefulness of skin tests in ruling out cross-reaction to cisplatin to continue platinum-based chemotherapy in patients who are responsive to these agents. Prick…
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Medical study · Medical research · 1989
Dusts causing pneumoconiosis generate .OH and produce hemolysis by acting as Fenton catalysts
…were studied. The authors tested whether dusts act as Fenton catalysts, turning hydrogen peroxide into damaging hydroxyl radicals, a reaction in which iron or other metals take part. With ascorbate (vitamin C) present, amosite, chrysotile and…
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Medical study · Medical research · 2001
Free radical generation in the toxicity of inhaled mineral particles: the role of iron speciation at the surface of asbestos and silica
…1.3 to 29 nmol/mg. It also increased one radical reaction, breaking a carbon-hydrogen bond, about 3-fold, while heating in air fully stopped that reaction. The other reaction, hydroxyl radical release from hydrogen…
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Medical study · Medical research · 1993
Radical oxidation reactions of the purine moiety of 2'-deoxyribonucleosides and DNA by iron-containing minerals
…was investigated by using a double experimental approach. One involved the electron spin resonance spin-trapping measurement of organic radicals obtained by the reaction of activated oxygen species, released upon incubation of the minerals in phosphate…
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Medical study · Medical research · 2000
Phospholipase A2-mediated superoxide production of murine peritoneal macrophages induced by chrysotile stimulation
…induced O(2) production, and (2) two different kinds of PLA(2) work upstream and downstream of PKC, but (3) G-protein, 5-LO and COX metabolites, and PAF have no modulatory role in the reaction.
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Medical study · Medical research · 2011
Auto-antibodies to β-F1-ATPase and vimentin in malignant mesothelioma
…against proteins from mesothelioma cell lines. They found no antibody reaction common to the patients. Serum from one patient strongly recognised proteins later identified as vimentin and the beta chain of ATP synthase (beta-F1-ATPase…
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Medical study · Medical research · 1983
Transmigration of ingested asbestos
…with crystals resembling amosite visible inside cells. Saline injected into two control rats caused a smaller reaction. Rats given 100 mg of amosite by stomach tube daily for 5 days showed no macrophage response or other…
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Medical study · Medical research · 1988
Adenomatoid tumour of the uterus
…EMA or CEA. The tumour cells did not stain for Factor VIII, unlike the blood vessels in the same sections. Many tumour cells showed a moderate reaction for keratin, and most, but not all, stained for…
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Medical study · Medical research · 1946
The effect of asbestos, and of asbestos and aluminium, on the lungs of rabbits
…body reaction in the lungs. Long fibres produced nodules that the authors compared with the experimental silicotic nodule. Short fibres produced widespread thickening of the alveolar walls. Aluminium increased and prolonged the foreign-body reaction and…
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Medical study · Medical research · 2009
Multiwalled carbon nanotube buckypaper: toxicology and biological effects in vitro and in vivo
…BP induced a moderate inflammatory reaction but had no mutagenic effects. After BP implantation the animals showed an inflammatory reaction followed 2 weeks later by a cicatrization reaction with the organization and fibrosis of the scar…
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Medical study · Medical research · 1995
Role of iron in the reactivity of mineral fibers
…chemical processes that implicate surface iron as a primary cause of toxicity are: free radical release, mobilization by chelators, iron-catalyzed reactions. Three kinds of solids are compared: (i) well-known toxic materials, for example asbestos…
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Medical study · Medical research · 2001
Sarcomatous mesothelioma in the left ventricle: a rare entity
…damaging the valve. Microscopic and immunohistochemical tests confirmed a sarcomatous (fibrous) mesothelioma, with a positive reaction to HBME-1. The patient recovered without complications and left hospital on the ninth day after surgery. At 3 months…
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Medical study · Medical research · 1985
Industrially acquired pulmonary disease
…79% had a smoking history, and none of the smokers stopped after learning of their increased risk. Denial of the danger was the most frequent reaction to risk information. In a later evaluation, 45% of 36…
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Company document · JM Document Review · April 3, 1985
Lois Gaul's Manville Memo on the Bureau of Mines Circular Mineral Wool (1985)
…R. Sayers of the U.S. Public Health Service: mineral-wool fibers produced "an inert foreign body reaction similar to that of asbestos," and the Service had been "considering dust from mineral wool as potentially harmful."
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Patent · February 20, 1979
Process for the preparation of ettringite fibers (US Patent 4,140,540, 1979)
…No. 4,002,484 but with enough water to assure having a suspension containing a maximum of 25% dry matter at the end of the reaction, and in subjecting said suspension to moderate stirring of 1…
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Company document · JM Knowledge Chronology · June 12, 1956
W. G. Hazard of Owens-Illinois to Ira I. Brought on Kaylo and the Saranac Experiments (1956)
…1948). Writing to an outside consultant, Hazard describes the finding as a mild reaction and compares Kaylo favorably with the asbestos dust insulators already breathed. The attached article is written up separately (Schepers, Durkan and Delahant…
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Company document · JM Knowledge Chronology · June 20, 1952
Arthur L. Fisk Jr. to Mrs. R. A. Duhamel and Dr. Fred C. Brock on Rock Wool Dermatitis (1952)
…infrequent and rare occasions has arisen in our factories in connection with the few people who are allergic to rock wool." He described four kinds of skin reaction seen from rock wool contact and their treatment.
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Medical study · Medical research · 2020
Unusually favorable outcome of 6 consecutive patients with diffuse malignant peritoneal mesothelioma treated with repeated doses of intraperitoneal paclitaxel. A case series
…died of disease 15 years after treatment. Three of the 6 had a grade III/IV adverse event: an inverted and then infected port, an intense allergic reaction, and a small bowel perforation. In 5 patients…
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Medical study · Medical research · 2022
Artichoke phytocomplex modulates serum microRNAs in patients exposed to asbestos: a first step of a phase II clinical trial
…193a-5p, also appeared in earlier mesothelioma data. Of 21 men who took AWPC, 11 reported at least one adverse reaction. None were considered serious. AWPC was suspected as the cause in 3 men, all of…