223 results for “Reaction Department”, page 3 of 12
-
Medical study · Medical research · 1988
Adenomatoid tumour of the uterus
…EMA or CEA. The tumour cells did not stain for Factor VIII, unlike the blood vessels in the same sections. Many tumour cells showed a moderate reaction for keratin, and most, but not all, stained for…
-
Medical study · Medical research · 2001
Sarcomatous mesothelioma in the left ventricle: a rare entity
…damaging the valve. Microscopic and immunohistochemical tests confirmed a sarcomatous (fibrous) mesothelioma, with a positive reaction to HBME-1. The patient recovered without complications and left hospital on the ninth day after surgery. At 3 months…
-
Medical study · Medical research · 2020
Unusually favorable outcome of 6 consecutive patients with diffuse malignant peritoneal mesothelioma treated with repeated doses of intraperitoneal paclitaxel. A case series
…died of disease 15 years after treatment. Three of the 6 had a grade III/IV adverse event: an inverted and then infected port, an intense allergic reaction, and a small bowel perforation. In 5 patients…
-
Medical study · Medical research · 2022
Artichoke phytocomplex modulates serum microRNAs in patients exposed to asbestos: a first step of a phase II clinical trial
…193a-5p, also appeared in earlier mesothelioma data. Of 21 men who took AWPC, 11 reported at least one adverse reaction. None were considered serious. AWPC was suspected as the cause in 3 men, all of…
-
Medical study · Medical research · 2016
A regional approach for CAR T-cell therapy for mesothelioma: from mouse models to clinical trial
…at 196 days. In an earlier intravenous Phase I trial that included three MPM patients, all three developed antibodies and one had an anaphylactic reaction. The authors described their ongoing Phase I trial (NCT02414269), which gives…
-
Medical study · Medical research · 1979
Milky spots (Taches laiteuses) as structures which trap asbestos in mesothelial layers and their significance in the pathogenesis of mesothelial neoplasia
…were seen in either group. The authors concluded that milky spots may trap blood-borne particles. They suggested that the cells' reaction to trapped fibres might be an early step toward tumours of the body cavities.
-
Medical study · Medical research · 2001
Cutaneous toxicity after intradermal vaccination with Mycobacterium vaccae against lung cancer and malignant mesothelioma
This letter reported two patients at the Royal Marsden Hospital who developed unusual skin reactions after injections into the skin of SRL172, a heat-killed Mycobacterium vaccae vaccine being tested against cancer. The first, a 52…
-
Medical study · Medical research · 2013
Melan A (A103) is not a marker of mesothelioma
…supplier (Lab Vision). The authors concluded that melan A (A103) is not expressed in mesotheliomas and that the earlier positive results most likely reflected a false-positive reaction of that antibody. The study did not examine…
-
Medical study · Medical research · 2003
Regression of AK7 malignant mesothelioma established in immunocompetent mice following intratumoral gene transfer of interferon gamma
…10% with a control virus. The authors concluded that local interferon gamma had antitumor activity in this model. They noted that the immune reaction was not enough to produce an efficient memory response, since tumors relapsed.
-
Medical study · Medical research · 2017
Malignant peritoneal mesothelioma and Crohn disease
Mesothelial reaction simulating peritoneal diffuse malignant mesothelioma (MM) has been reported in the setting of Crohn ileitis. To our knowledge, peritoneal MM arising in patients with inflammatory bowel disease (IBD) has not been reported. The purpose…
-
Medical study · Medical research · 2000
Epithelial mesothelioma with deciduoid features: report of four cases
Deciduoid mesothelioma is the designation given to an unusual morphologic variant of epithelial mesothelioma that closely simulates exuberant ectopic decidual reaction. Because all four previously reported cases involved the peritoneum and occurred in young women without…
-
Medical study · Medical research · 2016
SORORIN and PLK1 as potential therapeutic targets in malignant pleural mesothelioma
…molecular targets for the development of more effective therapies for MPM. Using quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR) and an RNA interference-based screening, we examined the SORORIN gene as potential therapeutic targets for…
-
Medical study · Medical research · 1986
Distinct keratin patterns demonstrated by immunoperoxidase staining of adenocarcinomas, carcinoids, and mesotheliomas using polyclonal and monoclonal anti-keratin antibodies
…10 adenocarcinomas, 10 carcinoids, and 4 mesotheliomas by an immunoperoxidase reaction using 3 polyclonal and 3 monoclonal antibodies to keratin. When color development in diaminobenzidine (DAB) was allowed to proceed for less than 2 minutes, distinct…
-
Medical study · Medical research · 1990
Mesothelial proliferation due to asbestos and man-made fibres. Experimental studies on rat omentum
…in rats has proven to be an appropriate method controlling fibrogenicity and carcinogenicity of asbestos fibres and other fibrous dusts. We analyzed the reaction patterns of mesothelial cover layer to different natural mineral fibres (crocidolite, chrysotile…
-
Medical study · Medical research · 2013
Diagnostic usefulness of p16/CDKN2A FISH in distinguishing between sarcomatoid mesothelioma and fibrous pleuritis
…examination is inconclusive. We studied the usefulness of deletion of p16 with fluorescence in situ hybridization (FISH) and p16 hypermethylation with polymerase chain reaction for the diagnosis and prognosis of malignant pleural mesothelioma (MPM). We analyzed…
-
Medical study · Medical research · 2011
Aromatase inhibitor exemestane has antiproliferative effects on human mesothelioma cells
…aromatase (CYP19A1) in malignant mesothelioma (MM). We found CYP19A1 in five human MM cell lines using reverse transcription polymerase chain reaction and Western immunoblots and in a group of samples from patients with MM by immunohistochemistry…
-
Medical study · Medical research · 2010
Complete regression of human malignant mesothelioma xenografts following local injection of midkine promoter-driven oncolytic adenovirus
…the tumor-specific midkine (Mdk) promoter could confer transcriptional targeting to oncolytic adenoviruses for effective treatment of malignant mesothelioma. We analysed Mdk expression by quantitative reverse transcription-polymerase chain reaction in six human mesothelioma cell lines…
-
Medical study · Medical research · 2001
Absence of SV-40 large T antigen (Tag) in malignant mesothelioma effusions: an immunocytochemical study
…a function of a nuclear protein, the large T antigen (Tag). SV-40 Tag DNA sequences are detected by the polymerase chain reaction in 40-80% of malignant mesothelial proliferations. However, the role of immunohistochemistry (IHC…
-
Court case · California Court of Appeal · March 17, 2017 · in the opinion
Phillips v. Honeywell International Inc. (2017)
…goal of installing brakes weakens the inference that Phillips reaction to a warning on the boxes of Bendix brakes would have been the same as his reaction to the warning on cigarette packaging when he started…
-
Medical study · Medical research · 2016
Functional Analysis of the Adrenomedullin Pathway in Malignant Pleural Mesothelioma
…protein 2 (CLR/RAMP2) and calcitonin receptor-like receptor/receptor activity-modifying protein 3 (CLR/RAMP3). Real time quantitative reverse transcriptase polymerase chain reaction (RT-PCR) was used to assess the steady-state levels of AM…