558 results for “Reaction Department”, page 7 of 28
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Medical study · Medical research · 1976
Nephrogenic metaplasia (adenomatoid tumors) of bladder
…23 men and 5 women. The authors concluded that their cases appear to support the theory that these lesions are a reaction of the bladder lining to chronic inflammation or irritation. They considered it likely that…
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Medical study · Medical research · 2003
Ascorbic acid modifies the surface of asbestos: possible implications in the molecular mechanisms of toxicity
…consequence of the erosion of the outmost layers while hydration of silica tetrahedra yields new silanol groups. The activity in the Fenton-like reaction (OH from H(2)O(2)) decreases following surface iron depauperation. Conversely…
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Medical study · Medical research · 2010
Pleural granuloma mimicking malignancy 42 years after slurry talc injection for primary spontaneous pneumothorax
…malignant cells or asbestos fibers. Keyhole surgery was converted to open surgery and the pleura was removed. The pathologist diagnosed chronic granulomatous pleuritis caused by a foreign body reaction, likely talc. Only on detailed questioning did…
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Medical study · Medical research · 2008
Detection of chrysotile asbestos by using a chrysotile-binding protein
…m' elsewhere. In rockwool mixed with chrysotile, the bound protein was released from the washed sample and then reacted: a one-minute color reaction detected 1% chrysotile, and a 30-minute incubation detected 0.1%. The…
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Medical study · Medical research · 1996
Simian virus 40 large T antigen (SV40LTAg) primer specific DNA amplification in human pleural mesothelioma tissue
…and three reactive pleurae, and amplified by the polymerase chain reaction (PCR) using the primer pairs used previously on fresh frozen tissues-namely, the SV primer set directed at the LTAg gene sequence unique to SV40…
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Medical study · Medical research · 1965
Talco-silicosis in a rubber worker
…golden-brown asbestos bodies, and the lymph nodes held crystals presumed to be silica. The authors judged the lesions typical of a reaction to impure talc, with features of both silicosis and asbestosis. He had worked…
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Medical study · Medical research · 1982
"Labrador lung": an unusual mixed dust pneumoconiosis
…ferruginous bodies; one ferruginous body was identified as having a core of anthophyllite. A granulomatous reaction was seen in two biopsy specimens and typical silicotic nodules were found in two others. The relatively brief exposure, especially…
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Medical study · Medical research · 2010
Administration of cisplatin in three patients with carboplatin hypersensitivity: is skin testing useful?
…of treatment. The aim of this study was to determine the usefulness of skin tests in ruling out cross-reaction to cisplatin to continue platinum-based chemotherapy in patients who are responsive to these agents. Prick…
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Medical study · Medical research · 1989
Dusts causing pneumoconiosis generate .OH and produce hemolysis by acting as Fenton catalysts
…were studied. The authors tested whether dusts act as Fenton catalysts, turning hydrogen peroxide into damaging hydroxyl radicals, a reaction in which iron or other metals take part. With ascorbate (vitamin C) present, amosite, chrysotile and…
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Medical study · Medical research · 2001
Free radical generation in the toxicity of inhaled mineral particles: the role of iron speciation at the surface of asbestos and silica
…1.3 to 29 nmol/mg. It also increased one radical reaction, breaking a carbon-hydrogen bond, about 3-fold, while heating in air fully stopped that reaction. The other reaction, hydroxyl radical release from hydrogen…
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Medical study · Medical research · 1993
Radical oxidation reactions of the purine moiety of 2'-deoxyribonucleosides and DNA by iron-containing minerals
…was investigated by using a double experimental approach. One involved the electron spin resonance spin-trapping measurement of organic radicals obtained by the reaction of activated oxygen species, released upon incubation of the minerals in phosphate…
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Medical study · Medical research · 2000
Phospholipase A2-mediated superoxide production of murine peritoneal macrophages induced by chrysotile stimulation
…induced O(2) production, and (2) two different kinds of PLA(2) work upstream and downstream of PKC, but (3) G-protein, 5-LO and COX metabolites, and PAF have no modulatory role in the reaction.
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Medical study · Medical research · 2011
Auto-antibodies to β-F1-ATPase and vimentin in malignant mesothelioma
…against proteins from mesothelioma cell lines. They found no antibody reaction common to the patients. Serum from one patient strongly recognised proteins later identified as vimentin and the beta chain of ATP synthase (beta-F1-ATPase…
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Medical study · Medical research · 1983
Transmigration of ingested asbestos
…with crystals resembling amosite visible inside cells. Saline injected into two control rats caused a smaller reaction. Rats given 100 mg of amosite by stomach tube daily for 5 days showed no macrophage response or other…
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Medical study · Medical research · 1988
Adenomatoid tumour of the uterus
…EMA or CEA. The tumour cells did not stain for Factor VIII, unlike the blood vessels in the same sections. Many tumour cells showed a moderate reaction for keratin, and most, but not all, stained for…
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Medical study · Medical research · 1946
The effect of asbestos, and of asbestos and aluminium, on the lungs of rabbits
…body reaction in the lungs. Long fibres produced nodules that the authors compared with the experimental silicotic nodule. Short fibres produced widespread thickening of the alveolar walls. Aluminium increased and prolonged the foreign-body reaction and…
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Medical study · Medical research · 2009
Multiwalled carbon nanotube buckypaper: toxicology and biological effects in vitro and in vivo
…BP induced a moderate inflammatory reaction but had no mutagenic effects. After BP implantation the animals showed an inflammatory reaction followed 2 weeks later by a cicatrization reaction with the organization and fibrosis of the scar…
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Medical study · Medical research · 1995
Role of iron in the reactivity of mineral fibers
…chemical processes that implicate surface iron as a primary cause of toxicity are: free radical release, mobilization by chelators, iron-catalyzed reactions. Three kinds of solids are compared: (i) well-known toxic materials, for example asbestos…
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Medical study · Medical research · 2001
Sarcomatous mesothelioma in the left ventricle: a rare entity
…damaging the valve. Microscopic and immunohistochemical tests confirmed a sarcomatous (fibrous) mesothelioma, with a positive reaction to HBME-1. The patient recovered without complications and left hospital on the ninth day after surgery. At 3 months…
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Medical study · Medical research · 1985
Industrially acquired pulmonary disease
…79% had a smoking history, and none of the smokers stopped after learning of their increased risk. Denial of the danger was the most frequent reaction to risk information. In a later evaluation, 45% of 36…