Journal of Surgical Case Reports

Our medical research library holds 30 studies published in Journal of Surgical Case Reports (2012–2026). Each entry links to the study's record on PubMed and, where there is one, to the publisher's page and a free full text. 30 have an abstract, the authors' own summary as PubMed records it: open "Abstract" to read it.

About the journal

• Publisher: Oxford University Press
• Published: 2010 to the present, England
• Language: English
• ISSN: 2042-8812 (electronic)
• Its record in the NLM Catalog

2020s

• Benign multicystic peritoneal mesothelioma presenting as a retroperitoneal pelvic mass in a young woman: a case report. E.A. Amaireh, O. Al-Natour, M.A. Nour, et al. 2026;2026(8):rjag710. Case report PubMed · Publisher · Free full text

  Abstract

  Benign multicystic peritoneal mesothelioma is a rare mesothelial neoplasm with fewer than 200 reported cases, typically arising on peritoneal or pelvic surfaces in premenopausal women. We describe a 21-year-old woman with a 2-week history of left lower abdominal pain. Magnetic resonance imaging showed a multiloculated cystic retroperitoneal mass adherent to the sigmoid colon, with normal ovaries and uterus. CA-125 was mildly elevated. At laparotomy, the mass was confirmed to be retroperitoneal without ovarian involvement, requiring en-bloc excision with sigmoid colectomy and primary anastomosis. Histopathology showed flat-to-cuboidal mesothelial cells with a hobnailing pattern in fibromyxoid stroma; immunohistochemistry was positive for calretinin and WT-1, and negative for SALL4, GATA3, and CD31, confirming benign multicystic peritoneal mesothelioma. At 6-month follow-up she remained asymptomatic with no recurrence on imaging. This case highlights BMPM as a mimicker of primary retroperitoneal neoplasms and the potential need for bowel resection to achieve complete excision.

  © The Author(s) 2026. Published by Oxford University Press and JSCR Publishing Ltd.

• Cytoreductive surgery and HIPEC for multicystic peritoneal mesothelioma: therapeutic approach in a rare benign neoplasm. G. Aleksandrić, N. Trifunović, J. Trifunović, et al. 2026;2026(1):rjaf1041. Case report PubMed · Publisher · Free full text

  Abstract

  Multicystic peritoneal mesothelioma (MCPM) is an uncommon tumor of mesothelial origin, characterized by multiple interconnected cystic spaces and uncertain biological behavior. Although traditionally considered benign, its tendency to recur and occasionally spread within the peritoneal cavity challenges this perception. We describe a 32-year-old woman who experienced gradually worsening pelvic pain and a constant feeling of pressure, which intensified after childbirth. Imaging revealed a large multilocular cystic mass occupying the pelvis. At laparotomy, a gelatinous, multilocular lesion was found adherent to the pelvic peritoneum, uterus, ovaries, and rectosigmoid colon. Complete cytoreductive surgery was performed, including pelvic peritonectomy, omentectomy, appendectomy, and resection of the affected serosa, followed by closed-abdomen hyperthermic intraperitoneal chemotherapy (HIPEC) with oxaliplatin (300 mg/m2, 42°C, 90 min). Histopathology confirmed benign multicystic mesothelioma with a mesothelial immunophenotype. The patient recovered well and remains disease-free at 6 months. MCPM requires complete cytoreduction, and HIPEC may help achieve lasting disease control.

  © The Author(s) 2026. Published by Oxford University Press and JSCR Publishing Ltd.

• Multicystic peritoneal mesothelioma mimicking recurrent pseudomyxoma peritonei. A. Scarton, M. Tonello, E. Pizzolato, et al. 2026;2026(7):rjag525. Case report PubMed · Publisher · Free full text

  Abstract

  Multicystic peritoneal mesothelioma (MCPM) is a borderline variant of peritoneal mesothelioma with indolent behaviour but a significant recurrence rate without radical treatment. Due to its rarity, risk factors and optimal treatment are still to clarify. The present clinical case is a report of MCPM developed after laparoscopic cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (Lap CRS-HIPEC) for pseudomyxoma peritonei (PMP) of appendiceal origin. The patient was treated for PMP with Lap CRS-HIPEC. One year later a recurrence was suspected at the thorax-abdomen computed tomography scan. After multidisciplinary discussion, she underwent iterative Lap CRS-HIPEC. Pathological examinations revealed MCPM. After 3 years of follow-up the patient is disease-free for both tumours. This is a unique case of MCPM mimicking recurrent PMP. Lap CRS-HIPEC is an effective approach for both conditions.

  © The Author(s) 2026. Published by Oxford University Press and JSCR Publishing Ltd.

• Peritoneal mesothelioma as an incidental finding during inguinal hernia surgery. J.R. Andresen, E.L. Monteiro, M.O. Liedke. 2026;2026(1):rjaf1055. Case report PubMed · Publisher · Free full text

  Abstract

  Malignant peritoneal mesothelioma is a rare tumor disease, usually associated with asbestos exposure, which is often only diagnosed at an advanced stage. We report the case of a 52-year-old patient who was found to have marked ascites during surgery for a recurrent inguinal hernia. Subsequent diagnostics, including diagnostic laparoscopy, established the diagnosis of malignant epithelioid peritoneal mesothelioma. After tumor reduction by omentum resection and hyperthermic intraperitoneal chemotherapy, a complete remission was achieved. The case underlines the importance of differentiated clarification of unclear intra-abdominal findings in high-risk patients with possible asbestos exposure.

  © The Author(s) 2026. Published by Oxford University Press and JSCR Publishing Ltd.

• Incidental finding of metastatic mesothelioma in an inguinal hernia sac: a case report. A. Al-Bitar, M. Shwin. 2025;2025(2):rjaf099. Case report PubMed · Publisher · Free full text

  Abstract

  Inguinal hernias are the most common type of abdominal wall hernias, often requiring surgical intervention. Mesothelioma, a rare cancer associated with the linings of serous cavities, can occasionally be found in hernia sacs. This paper presents the case of a 38-year-old male with an incidental diagnosis of stage 4 pleural mesothelioma discovered during a routine inguinal hernia repair. Despite being asymptomatic, the patient's hernia sac examination revealed mesothelioma, which was confirmed through histopathological analysis and imaging. This rare finding underscores the importance of thorough examination and comprehensive oncological evaluation when unusual findings are encountered during routine surgeries. The case highlights the necessity for awareness and vigilance in similar scenarios to potentially improve patient outcomes.

  Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2025.

• Salvage resection after immunotherapy for giant undifferentiated pleomorphic sarcoma of the chest wall. A. Nakamura, A. Kuroda, M. Hashimoto, et al. 2025;2025(10):rjaf747. Case report PubMed · Publisher · Free full text

  Abstract

  We present a rare case of primary undifferentiated pleomorphic sarcoma (UPS) of the chest wall in a 45-year-old male, initially diagnosed as sarcomatoid pleural mesothelioma via computed tomography (CT)-guided biopsy. CT revealed a large tumor measuring 13 × 12 cm occupying the left thoracic cavity, with extensive invasion into the left first through fifth ribs and the adjacent lung parenchyma. The patient was referred to our hospital and treated with a combination of nivolumab and ipilimumab, resulting in marked tumor regression. Upon reevaluation, the diagnosis was revised to sarcoma, and the patient subsequently underwent salvage surgery, including resection of the left upper lung lobe and first through fifth ribs. Histopathology confirmed tumor mutational burden-high UPS. The patient has remained disease-free for two and a half years postoperatively. This case demonstrates the potential efficacy of immune checkpoint inhibitors in multimodal treatment for select cases of chest wall UPS.

  © The Author(s) 2025. Published by Oxford University Press and JSCR Publishing Ltd.

• A case of benign multicystic peritoneal mesothelioma. J. Wassef, J. Kim, T. Farag, et al. 2024;2024(10):rjae629. Case report PubMed · Publisher · Free full text

  Abstract

  Benign Multicystic Peritoneal Mesothelioma (BMPM) is an exceedingly rare benign abdominal neoplasm with fewer than 200 cases reported worldwide. Owing to its rarity, vague clinical picture, and elusive causes, diagnosis is often delayed or missed. Histopathological examination and immunohistochemical staining are crucial for definitive diagnosis. However, due to lack of substantial literature, the standard of care and future prognosis remain subjects of inquiry. We present a case report of one female patient diagnosed with BMPM and treated with surgical resection.

  Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2024.

• A peculiar presentation of tamponade: pericardial mesothelioma. S.D. Syed Ahmad, F. Kirk, W. Wijesinghe, et al. 2024;2024(5):rjae279. Case report PubMed · Publisher · Free full text

  Abstract

  Pericardial mesothelioma (PM) is rare with only 200 cases recorded, and a post-mortem prevalence of <0.0022%. It is the third most common cardiac/pericardial tumour, behind angiosarcoma and rhabdomyosarcoma. PM incidence increases with age, typically incidentally diagnosed between 50 and 70 years, with a 3:1 male predominance. Occasional PM can cause chest pain, dyspnoea, cough and even dysphagia. PMs are often misdiagnosed with only 25% of cases being antemortem diagnoses. Unlike pleural mesothelioma, the link between asbestos exposure and malignancy is less convincing, with only 20% of cases having known exposure. 6 There are three histological types: epithelioid, fibrous (spindle cell), and biphasic (mixed). The average life-expectancy post diagnosis is 3-10 months. Due to the heterogeneity of the presentation and rarity there is no standardized management algorithm, and the diagnostic imaging or laboratory investigations are scarcely described. We are presenting one of the cases diagnosed in our unit here in the Gold Coast.

  Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2024.

• Comprehensive genomic profiling of pediatric peritoneal mesothelioma: case report with a literature review. J. Redzepagic, Z. Zvizdic, N. Bilalovic, et al. 2024;2024(5):rjae324. Case report PubMed · Publisher · Free full text

  Abstract

  Malignant peritoneal mesothelioma is an extremely rare and poorly recognized neoplasm in children. A 5-year-old boy presented with a 1-year history of progressive painless abdominal distension. A CT revealed a 19 × 19 × 11 cm3 cystic mass in the right hemiabdomen, without infiltrating the surrounding structures. The tumor was completely removed by surgery. The microscopic and immunohistochemical analyses confirmed peritoneal mesothelioma. Comprehensive genomic profiling revealed no major driving mutations including BAP1, no fusions, but with amplifications of AURKA, AURKC, HLA-1B, ZNF-217, OR5F1 and MEN1 genes. Imaging follow-up 3 months after surgery revealed metastatic disease. The patient died of pneumonia at another hospital shortly after the last follow-up examination at our institution. Pediatric peritoneal mesothelioma is an extremely rare malignancy with limited targeted options and a poor prognosis. Some of the identified molecular genomic biomarkers require further exploration and validation in this cancer.

  Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2024.

• Peritoneal inclusion cyst presenting as an umbilical hernia: case report and systematic review of the literature. K. Nightingale, E. Clough, P. Goldsmith, et al. 2024;2024(5):rjae258. Case report PubMed · Publisher · Free full text

  Abstract

  Peritoneal inclusion cysts (PICs) are a rare and benign condition of uncertain pathogenesis. The fluid-filled, mesothelial-lined cysts manifest within the abdominopelvic cavity. This case report details an unusual occurrence of a 97 mm PIC- presenting as an umbilical hernia- in a 26-year-old male patient with no prior surgical history. Following pre-operative cross-sectional imaging, this was managed through open excision without complication. A systematic review of the literature highlighted 30 previous cases [26F, 4M] with a mean age of 34 years (std ±15.4) and a median diameter of 93 mm [IQR, 109 mm]. A total of 53% (n = 16) of cases had a history of previous abdominal surgery. Surgical excision is safe and laparoscopic modality should be considered (<1% recurrence). Accepting the limited evidence base, image guided drainage should be avoided (50% recurrence, n = 2).

  Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2024.

• Rare confounder: benign multicystic peritoneal mesothelioma in a patient with mucinous colon adenocarcinoma. K.K. Patel, G.P. Stinson, K.P. Terracina, et al. 2024;2024(9):rjae569. Case report PubMed · Publisher · Free full text

  Abstract

  Benign multicystic peritoneal mesothelioma (BMPM) is a rare condition, in which patients have multiple cystic lesions of the peritoneum. BMPM can mimic mucinous carcinomatosis and can thus create a diagnostic dilemma. We present the case of a 76-year-old woman who was referred for management of ascending colon adenocarcinoma and was noted to have several nonspecific cystic lesions in the abdomen and pelvis on preoperative computed tomography and diagnostic laparoscopy. Frozen section analysis suggested the lesions contained 'mucin'. Due to concern for metastases, right colectomy was aborted. Final histologic analysis of the laparoscopic biopsies revealed mesothelial cysts, consistent with BMPM, unrelated to her colon adenocarcinoma. Laparoscopic right colectomy was performed 2 weeks later. BMPM can create diagnostic and therapeutic uncertainty in patients with known visceral malignancies when discovered incidentally. Frozen section analysis may not be accurate in differentiating the two, and final histologic confirmation should be sought prior to definitive treatment.

  Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2024.

• Primary splenic multicystic peritoneal mesothelioma in a young healthy male. M.D. Price, S. Nair, J. Harris. 2023;2023(10):rjad551. Case report PubMed · Publisher · Free full text

  Abstract

  Multicystic peritoneal mesothelioma (BMPM) is a rare, usually benign tumor that arises from peritoneal mesothelial cells that most commonly occurs in women of reproductive age. Pathogenesis of these tumors is thought to come from chronic inflammation from prior surgery, endometriosis, trauma, or recurrent peritonitis. Here we report a case of primary splenic BMPM in a 20-year-old male with no past medical or surgical history and without any typical risk factors for this condition. He underwent an open splenectomy without complication. Pathology revealed an 18 × 4 × 11 cm3 spleen with a cyst occupying 75% of the splenic surface. Sections revealed a multilocular cyst with trabeculated walls and immunohistochemical staining positive for cytokeratin (AE1/AE3) consistent with BMPM. One year post operatively he remains asymptomatic; however, his interval computed tomography (CT) scan revealed several sub centimeter nodules that either represents small splenules or neoplastic implants. These will be followed with close interval imaging.

  Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2023.

• Thinking outside the pelvis: benign peritoneal multicystic mesothelioma of the ascending colon. B. Murphy, M. Ismaeil, D.C. Winter. 2023;2023(9):rjz328. Case report PubMed · Publisher · Free full text

  Abstract

  Benign peritoneal multicystic mesothelioma is a rare tumor of the visceral peritoneum. The authors present an atypical case of a 74-year-old man who presented with a multicystic mesothelioma of the ascending colon.

  Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2019.

• Acute presentation of multi-cystic peritoneal mesothelioma. M. Redden, A. Riddell. 2022;2022(1):rjab627. Case report PubMed · Publisher · Free full text

  Abstract

  Multi-cystic peritoneal mesothelioma (MCPM) is a rare intra-abdominal neoplasm that occurs most commonly in young females. The disease usually presents as an incidental finding or with sub-acute abdominal pain. The mainstay of treatment is complete excision; however, local recurrence frequently occurs and malignant transformation has been reported. We describe a unique case of MCPM that presented with acute abdominal pain. A 32-year-old female presented with a 24-hour history of abdominal pain. Computed tomography abdomen demonstrated a low-density mass with surrounding inflammatory changes anterior to the ascending colon, which was initially thought to represent an abscess. A percutaneous drain was inserted; however, only clear fluid was aspirated and the lesion did not resolve. The patient subsequently underwent laparoscopy which identified a cystic structure overlying the ascending colon. The structure was excised whole with histology demonstrating MCPM. The patient recovered from surgery and will undergo a period of surveillance.

  Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2022.

• Cerebral metastases of malignant mesothelioma. A. Bathini, D.M. Kusyk, K. Stabingas, et al. 2022;2022(2):rjac002. Case report PubMed · Publisher · Free full text

  Abstract

  Malignant pleural mesothelioma represents a rare etiology of lung cancer metastasis to the brain. Neurologically symptomatic presentations are extremely rare as these metastatic lesions are detected in the late stages of the disease. Despite many highly heterogenous treatment techniques reported in the literature, overall survival is poor. A 72-year-old male with a history of mesothelioma presented with recurrent episodes of altered mental status, confusion and expressive aphasia. Imaging indicated a large hemorrhagic, enhancing lesion in the anterior left frontal lobe resulting in midline shift of 6 mm. He underwent a left frontal craniotomy for resection, after which he had complete resolution of symptoms. The resected mass was metastatic high-grade malignant mesothelioma. On a 1-month follow-up, new lesions in the bilateral frontal lobes were discovered, and despite undergoing adjuvant stereotactic radiosurgery, the right one grew significantly, causing notable mass effect. The patient successfully underwent a right craniotomy for resection.

  Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2022.

• Malignant peritoneal mesothelioma-a diagnostic challenge. S. Abdul Razzak, F. Awan, S. Ahmed. 2022;2022(12):rjac555. Case report PubMed · Publisher · Free full text

  Abstract

  Malignant peritoneal mesothelioma is a rare cancer originating primarily from the peritoneum with a poor prognosis and non-specific clinical presentation. We present a case of a 60-year-old male, retired metallurgy engineer who initially presented with shortness of breath, lethargy, weight loss, vague abdominal pain and night sweats. Extensive workup for almost 2 months finally leads to the diagnosis of primary malignant peritoneal mesothelioma based on immunohistochemical analysis of loss of BAP1 gene. The patient was deemed non-suitable for surgical management and started on palliative carboplatin and pemetrexed. In conclusion, histological diagnosis is essential for peritoneal diseases before considering it as a metastasis from other primary tumours. Furthermore, immunohistochemical analysis and genetic profiling may also guide towards the diagnosis and possible treatment.

  Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2022.

• Peritoneal mesothelioma causing small bowel obstruction in COVID-19 positive patient. A. Trivedi, A. Hlayhel, Z. Hooda, et al. 2022;2022(10):rjac469. Case report PubMed · Publisher · Free full text

  Abstract

  Mesothelioma is a disease process that can present in a variety of locations including the pleural, peritoneum and pericardium. Malignant peritoneal mesothelioma has been known to be a particularly aggressive type of tumor. We report a case of a patient who presented with a small bowel obstruction whose pathology revealed peritoneal malignant mesothelioma.

  Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2022.

• Sarcomatoid mesothelioma: unusual findings and literature review. B. Clopton, W. Long, M. Santos, et al. 2022;2022(11):rjac512. Case report PubMed · Publisher · Free full text

  Abstract

  Sarcomatoid mesothelioma is an aggressive disease secondary to its propensity to undergo rapid growth, show inconsistent expression of tumor markers and invade surrounding tissues. Therefore, there are numerous obstacles that clinical researchers face as they look for new methods to diagnose and treat the malignancy. We present a case of sarcomatoid mesothelioma, originally thought to be metastasis from renal cell carcinoma.

  Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2022.

• An unusual presentation of acute abdomen: infarcted peritoneal cyst-a probable asbestos-related benign cystic mesothelioma. V. Muralidhar. 2021;2021(4):rjab129. Case report PubMed · Publisher · Free full text

  Abstract

  This is a report of a rare case of an infarcted pelvic intra-abdominal cyst, having no mesenteric connection presenting as an acute abdomen. The patient had significant asbestos exposure. The cyst was treated successfully by surgical excision. Histopathology showed an infarcted cyst; the lining was destroyed, precluding marker studies. A diagnosis of benign cystic peritoneal mesothelioma (BCPM) was made by excluding other causes of solitary pelvic intra-abdominal cysts. BCPM has been classified as an asbestos-related neoplasm and is usually seen in the pelvis adjunct to the urinary bladder. One-year post-surgery, there was no recurrence. The case report shows that infarcted pelvic mesothelial cysts can present as an acute abdomen and can be treated successfully by total excision with no recurrence.

  Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2021.

• Intussusception caused by small intestine metastasis of malignant pleural mesothelioma: a case report. M. Hamaoka, M. Nakagawa, H. Nakahara, et al. 2021;2021(2):rjab003. Case report PubMed · Publisher · Free full text

  Abstract

  Malignant pleural mesothelioma (MPM) is an aggressive form of malignant tumor that originates in the pleural mesothelioma and presents as a local disease in the affected hemithorax. Small intestine metastasis is a rare complication. Herein, the case of a patient with jejunal intussusception caused by small intestine metastasis of MPM has been reported. A 72-year-old man with MPM was admitted to our hospital for abdominal pain. Computed tomography revealed small intestine intussusception. An emergency surgery was performed, and the tumor and intussusception were located in the upper jejunum. Histopathological examination of the resected jejunum revealed that the tumor was a small intestinal metastasis of the MPM from the chest wall. This case showed that MPM may metastasize to the small intestine, and metastatic tumors may cause intussusception.

  Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2021.

• Peritoneal mesothelioma with invasion of the urinary bladder 20 years post radiation therapy for colon adenocarcinoma. N. Ong Mingjing, A.S. Asamu, K. Pace, et al. 2021;2021(9):rjab392. Case report PubMed · Publisher · Free full text

  Abstract

  We present the case of a 66-year-old male with a history of iatrogenic bladder injury and radiation therapy for colon adenocarcinoma 20 years prior. A computed tomography of the thorax, abdomen and pelvis, reported a presacral mass with invasion to the bladder, ureters and lymph nodes. An initial bladder biopsy was histologically inconclusive. A later biopsy taken during emergency bypass surgery for small bowel obstruction, while the patient was positive for coronavirus disease of 2019, concluded that the mass was a peritoneal mesothelioma of epithelioid origin. The combination management of cytoreductive surgery with intraperitoneal chemotherapy has been a near universal standard of care for epithelioid peritoneal mesothelioma provided that the patient is an appropriate candidate for surgical interventions. To the best of our knowledge, this is the first case report of malignant peritoneal mesothelioma as a second primary carcinoma, many years after exposure to radiation therapy for colon adenocarcinoma.

  Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2021.

• Cardiac herniation after extrapleural pneumonectomy. N. Nishizawa, T. Osaki, Y. Fukuichi, et al. 2020;2020(2):rjaa011. Case report PubMed · Publisher · Free full text

  Abstract

  Cardiac herniation is a fatal complication in patients undergoing pneumonectomy with pericardial resection. A 53-year-old man underwent right-sided extrapleural pneumonectomy for malignant pleural mesothelioma. He underwent right-sided pericardial resection and reconstruction with an expanded polytetrafluoroethylene sheet. Routine chest radiography performed 18 h postoperatively revealed cardiac herniation into the right-sided thoracic cavity. The patient was immediately transferred to the operating room, and the defect was repaired. He died of tumor progression. However, cardiac herniation did not recur over 2 years postoperatively.

  Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.

• Intra-abdominal cystic lymphangioma of the mesocolon sigmoids: a rare entity in adult patient woman. A. Guachilema Ribadeneira, Á.R.T. Monard, M.C. Endara, et al. 2020;2020(5):rjaa031. Case report PubMed · Publisher · Free full text

  Abstract

  The lymphangioma is a benign neoplasm, mostly connate, it occurs more often in children. It is more frequently located in the head-neck region, as well as in the armpit, and less frequently in the abdomen. The diagnosis, as well as their appearance is variant, they can be asymptomatic depending on the size. The signs on the physical exam are usually nonspecific and can look like an acute abdomen. Imaging tests used are the ultrasound and tomography, which determine the therapeutic behavior. The differential diagnosis should be made with other intra-abdominal injuries, such as cavernous hemangioma, mesotheliomas, pancreatic and ovarian tumors and even peritoneal hydatid cyst. The definitive treatment is surgical in most cases, with complete excision of the mass. The definitive diagnosis is obtained with the histopathological study of the surgical piece.

  Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.

• Metastatic pleural mesothelioma presenting initially as multiple gastric and colonic polyps. A. Alhumidi, A. Alqahtani. 2020;2020(7):rjaa203. Case report PubMed · Publisher · Free full text

  Abstract

  It is extremely rare for malignant mesothelioma to present as gastrointestinal polyps. This case report documents the presentation of malignant mesothelioma in a 72-year-old as rectal bleeding and weight loss. Endoscopically, there were multiple gastric and colonic polyps. Histopathologically, there were atypical cells in the lamina propria with benign surface epithelium. The cells tested positive for cytokeratin, calretinin and D2-40 and negative for CD45, CD117, Ber-EP4 and CEA, confirming the diagnosis of metastatic mesothelioma. A computed tomography scan of the chest showed nodular thickening of the left lower pleura that was compatible with a diagnosis of primary pleural mesothelioma. We conclude that metastatic mesothelioma can sometimes present as gastrointestinal polyps.

  Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.

• Sarcomatoid malignant peritoneal mesothelioma presenting as a localized mesenteric tumor with no previous asbestos exposure. Y.A. Notue, U.I. Mbessoh, G. Nganwa, et al. 2020;2020(10):rjaa419. Case report PubMed · Publisher · Free full text

  Abstract

  Sarcomatoid malignant peritoneal mesothelioma is the rarest and most lethal form of peritoneal mesothelioma. We present the case of a sarcomatoid malignant peritoneal mesothelioma presenting as a localized mesenteric tumor in a 54-year-old female with no previous asbestos exposure. This clinical presentation is extremely rare and is the first documented in Cameroon.

  Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.

2010s

• Benign multicystic mesothelioma arising from the tunica vaginalis. A. Lang, P. Chaudhri. 2019;2019(1):rjy361. Case report PubMed · Publisher · Free full text

  Abstract

  Benign multicystic mesothelioma is an extremely rare neoplasm usually arising from the visceral mesothelium of the peritoneal cavity typically presenting in young to middle-aged women. It has been deemed an indolent tumour with a possible heritable nature, but also a possible reactive neoplasm secondary to trauma. Diagnosis relies on identifying characteristic histology of cysts separated by loose connective tissue stroma and lined by pale, flat or cuboidal mesothelial cells. A 74-year-old male presented with a painless, enlarging scrotal swelling thought to be either an epididymal cyst or hydrocele. He underwent radical orchiectomy and benign multicystic mesothelioma of the tunica vaginalis was characterized on macroscopy and microscopic examination. The potential for malignant transformation of these tumours has not been demonstrated, but they are known to recur. This infrequent presentation of a rare and poorly understood tumour with description of histologic findings may allow for improved diagnosis in other cases.

• Benign Multicystic Peritoneal Mesothelioma (BMPM) as a rare cause of abdominal pain in a young male: case report and review of the literature. S. Gussago, P. Spina, A. Guerra. 2019;2019(3):rjz057. Case report PubMed · Publisher · Free full text

  Abstract

  Benign Multicystic Peritoneal Mesothelioma (BMPM) is a rare benign cystic neoplasm that arise from the peritoneum, typically found in young females (83%), with a high incidence of local recurrence after resection (almost 50% of cases). Fewer than 200 cases have been reported worldwide in 2017. Due to its rarity and the lack of a classical clinical presentation, the diagnosis pre-operatively is challenging; moreover a great part of the literature is composed of case reports and small group studies. Nowadays, guidelines are still not available, and treatment is en bloc resection of the lesion. Some authors suggest the use of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) associated with the surgical approach, even if comparative data on recurrence and complications are lacking. We report a case of BMPM diagnosed in a 40-year-old male who underwent an exploratory laparoscopy and complete excision of the neoformation. Pathology confirmed the presence of a BMPM.

• Mesothelioma subtypes of the tunica vaginalis: a rare case report and review of histological criteria. R. Rebecca, M.J. Connor, L. Sun, et al. 2019;2019(3):rjz040. Case report PubMed · Publisher · Free full text

  Abstract

  Well-differentiated papillary mesothelioma (WDPM) is a rare histological subtype of mesothelioma arising from the tunica vaginalis. We present a case of a 23-year-old male with a palpable para-testicular lump of 3 years duration. Scrotal exploration revealed a grossly abnormal cystic appearance of his tunica vaginalis. An excision biopsy confirmed WDPM of the tunica vaginalis. The three subtypes of mesothelial tumours of the tunica vaginalis are described by their distinct histological features, tumour growth and reported prognosis. A summary of immunohistochemistry and the surgical management across the disease spectrum is provided. Recent clarification of the histological criteria of WDPM provides the opportunity for surgeons to offer a limited approach to managing this indolent tumour that mimics malignant mesothelioma. However, the lack of evidence on recurrence and progression rates in WDPM restricts most surgeons to performing a radical orchidectomy, as was performed in this case.

• Cerebral metastasis from malignant pleural mesothelioma. M. El Molla, C. Gragnaniello, D. Al-Khawaja, et al. 2013;2013(9). Case report PubMed · Publisher · Free full text

  Abstract

  Malignant mesothelioma is an uncommon, highly invasive tumor derived from the mesothelial cells of pleura or peritoneum characterized by poor outcome. Mesothelioma was thought to metastasize locally only via direct invasion and not have distant spread. Distant metastases were discovered mostly on post-mortem examination. The authors present a case of 62-year-old man with pleural mesothelioma and brain metastasis.

  Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author 2013.

• Malignant mesothelioma of the tunica vaginalis. M. Abdelrahman, C. Dowling, K. O'Connor, et al. 2012;2012(5):2. PubMed · Publisher · Free full text

  Abstract

  Malignant mesothelioma of the tunica vaginalis is a rare but potentially fatal disease. Lack of characteristic clinical features and tumour markers makes the pre-operative diagnosis very difficult. A 54 year-old man with no history of exposure to asbestos presented with a short history of scrotal swelling and pain. Ultrasound revealed a suspicious nodularity involving his tunica vaginalis, suggestive of mesothelioma. Excisional biopsy revealed a malignant mesothelioma; hence the patient was treated with radical inguinal orchidectomy and hemiscrotectomy. We present a case of this rare tumour, its management and a review of the literature.

  © JSCR.

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