Japanese Journal of Radiology

Our medical research library holds 8 studies published in Japanese Journal of Radiology (2010–2026). Each entry links to the study's record on PubMed and, where there is one, to the publisher's page and a free full text. 8 have an abstract, the authors' own summary as PubMed records it: open "Abstract" to read it.

About the journal

• Publisher: Springer
• Published: 2009 to the present, Japan
• Language: English
• ISSN: 1867-1071 (print), 1867-108X (electronic)
• Continues: Radiation Medicine
• Its record in the NLM Catalog

2020s

• Pretreatment volume-based 18F-FDG PET/CT parameters as prognostic indicators in malignant peritoneal mesothelioma patients. K. Kitajima, K. Matsuda, H. Yokoyama, et al. 2026;44(7):1257-1262. PubMed · Publisher · Free full text

  Abstract

  Objective: This study was conducted to examine relationships of pretreatment volume-based quantitative 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) parameters with overall survival (OS) in malignant peritoneal mesothelioma (MPeM) patients.

  Materials And Methods: Data for 71 patients with FDG-avid MPeM who underwent pretreatment 18F-FDG PET/CT were retrospectively reviewed. The highest maximum standardized uptake value (SUVmax), metabolic tumor volume (WB MTV), and total lesion glycolysis (WB TLG) were calculated, including primary tumors and metastatic lesions. Relationships of clinicopathological factors (histological subtype, primary peritoneal disease form, abdominal nodal metastasis, extra-abdominal metastasis, treatment regimen), as well as volume-based quantitative PET/CT parameters with OS were evaluated using a Cox proportional hazards model and log-rank test.

  Results: Enrolled patients underwent follow-up for a mean period of 27.6 months (range 2.1-161.2 months, median 18.9 months), during which 49 (69.0%) died. Receiver operating characteristic curve analysis and log-rank testing indicated that those with high SUVmax (≥ 6.9), WB MTV (≥ 60), or WB TLG (≥ 230) had a significantly lower OS rate than patients with a low rate (< 6.9, < 60, < 230; p = 0.0002, p < 0.0001, p < 0.0001, respectively). Univariate analysis of all patients indicated an association of diffuse peritoneal disease form (p = 0.022), high level SUVmax (p = 0.0002), WB MTV (p < 0.0001), or WB TLG (p < 0.0001) level, extra-abdominal metastasis (p = 0.079) and treatment regimen (p = 0.058) with significantly shorter OS. Additionally, multivariate analysis results confirmed high WB MTV as an independent negative predictor (hazard ratio 2.51, 95% confidence interval 0.72-13.45; p = 0.039).

  Conclusions: These findings indicate that pretreatment volume-based quantitative 18F-FDG PET/CT parameters, especially whole-body MTV, may be useful as surrogate markers for MPeM prognosis.

  © 2026. The Author(s).

• An overview on multimodal imaging for the diagnostic workup of pleural mesothelioma. M. Gabelloni, L. Faggioni, M.C. Brunese, et al. 2024;42(1):16-27. Review PubMed · Publisher · Free full text

  Abstract

  Pleural mesothelioma (PM) is an aggressive disease that has a strong causal relationship with asbestos exposure and represents a major challenge from both a diagnostic and therapeutic viewpoint. Despite recent improvements in patient care, PM typically carries a poor outcome, especially in advanced stages. Therefore, a timely and effective diagnosis taking advantage of currently available imaging techniques is essential to perform an accurate staging and dictate the most appropriate treatment strategy. Our aim is to provide a brief, but exhaustive and up-to-date overview of the role of multimodal medical imaging in the management of PM.

  © 2023. The Author(s).

2010s

• Fatal pleural mesothelioma in Japan (2003-2008): evaluation of computed tomography findings. K. Kato, K. Gemba, N. Fujimoto, et al. 2016;34(6):432-8. PubMed · Publisher

  Abstract

  Purpose: The purpose of this study was to clarify the characteristic findings of mesothelioma at the time of diagnosis, and determine precautions and guidelines for diagnosing mesothelioma early in imaging studies.

  Materials And Methods: Overall, 327 patients with pleural mesothelioma were selected from 6030 patients who died of mesothelioma between 2003 and 2008 in Japan. Their imaging findings were examined retrospectively.

  Results: Plaques were found in 35 % of computed tomography (CT) scans. Asbestosis, diffuse pleural thickening, and rounded atelectasis were found in only seven (2 %), five (2 %), and two cases (1 %), respectively. Pleural thickening findings on CT scans were classified into four stages: no irregularity, mild irregularity, high irregularity, and mass formation. Overall, 18 % of cases did not show a clear irregularity. Localized thickening was observed in the mediastinal (77 %) and basal (76 %) pleura and in the interlobar fissure (49 %). Eight percent of cases did not have any thickening in these three areas.

  Conclusions: Upon examination of the CT scans at diagnosis, 18 % of mesothelioma cases did not show a clear irregularity. When diagnosing pleural effusion of unknown etiology, it is necessary to consider the possibility of mesothelioma even when no plaque and pleural irregularity are observed.

• Present and future roles of FDG-PET/CT imaging in the management of malignant pleural mesothelioma. K. Kitajima, H. Doi, K. Kuribayashi. 2016;34(8):537-47. Review PubMed · Publisher

  Abstract

  Positron emission tomography/computed tomography (PET/CT) integrated with 2-[(18)F]fluoro-2-deoxy-D-glucose ((18)F-FDG) has emerged as a powerful tool for combined metabolic and anatomic evaluations in clinical oncologic imaging. This review discusses the utility of (18)F-FDG PET/CT as a tool to manage patients with malignant pleural mesothelioma. We discuss different stages of patient management in malignant pleural mesothelioma, including diagnosis, initial staging, therapy planning, early treatment response assessment, re-staging, and prognosis.

• An unusual liver mass: primary malignant mesothelioma of the liver : CT and MRI findings and literature review. A. Serter, N. Buyukpinarbasili, O. Karatepe, et al. 2015;33(2):102-6. Case report · Review PubMed · Publisher

  Abstract

  Primary malignant mesothelioma of the liver is extremely rare, and radiologic features have been defined in only one case. We present radiologic findings of two cases which are pathologically proven as primary malignant mesothelioma of the liver. Malignant mesothelioma of the liver may be included in a differential diagnosis list if there is a heterogeneous, hemorrhagic and necrotic lesion in the liver, with peripheral serpiginous vascular structures and increasing septal enhancement in post-contrast images.

• Pseudomesotheliomatous lung cancer mimicking mesothelioma on ¹⁸F-FDG PET/CT images: report of 2 cases. T. Nakamori, S. Kosuda, Y. Kyoto, et al. 2013;31(8):542-5. Case report PubMed · Publisher

  Abstract

  The authors report two cases of pseudomesotheliomatous lung cancer (PLC) detected by (18)F-FDG PET/CT scan. (18)F-FDG PET/CT clearly revealed the extent of the disease in both cases, a case of adenocarcinoma of the lung and a case of squamous cell carcinoma of the lung. Intense (18)F-FDG uptake by the diffusely thickened pleurae and primary lesion was observed in both cases, and increased (18)F-FDG uptake by a pelvic bone metastasis was observed in the case of squamous cell carcinoma. Although PLC is indistinguishable from malignant pleural mesothelioma on (18)F-FDG PET/CT scans, (18)F-FDG PET/CT was helpful in identifying the primary focus of the PLCs and in staging the disease. Diagnostic image interpreters should be familiar with the (18)F-FDG PET/CT findings in PLC.

• Malignant pleural mesothelioma detected by spontaneous pneumothorax. A. Makidono, M. Matsusako, K. Oikado, et al. 2010;28(7):547-51. Case report PubMed · Publisher

  Abstract

  We report a middle-aged man, without occupational or environmental exposure to asbestos, who presented with spontaneous pneumothorax. Computed tomography showed a 13-mm right apical mass. He underwent tumorectomy and was diagnosed with malignant pleural mesothelioma. A local recurrence with multiple and diffuse pleural involvement later appeared. The patient eventually underwent panpleuropneumonectomy, recovered well, and has been doing well for 18 months.

• Preliminary study of positron emission tomography/computed tomography and plasma osteopontin levels in patients with asbestos-related pleural disease. S. Kurata, M. Ishibashi, K. Azuma, et al. 2010;28(6):446-52. PubMed · Publisher

  Abstract

  Purpose: The aim of this study was to compare the results of semiquantitative analysis by(18)F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) with plasma osteopontin levels in the same asbestos-related pleural disease population.

  Materials And Methods: A total of 17 patients with asbestos-related pleural disease were prospectively recruited. They underwent PET/CT, and plasma osteopontin levels were measured. The maximum standardized uptake value (SUVmax) was determined from the most active pleural lesion in each patient.

  Results: Malignant pleural mesothelioma (MPM) was histologically proven in 6 patients, and 11 patients had proven benign asbestos-related pleural diseases (7 pleural plaques, 4 asbestos pleurisy). Significant differences in SUVmax were found between patients with MPM and those with asbestos pleurisy (P = 0.031) and between patients with MPM and those with pleural plaques (P = 0.012). A significant difference was found in the plasma osteopontin levels between patients with asbestos pleurisy and patients with pleural plaques (Bonferroni correction, P = 0.024). The SUVmax in patients with benign asbestos-related diseases was statistically positively correlated with plasma osteopontin in the same group (Spearman's r = 0.75, P < 0.05).

  Conclusion: PET/CT might be more helpful than plasma osteopontin for distinguishing benign asbestos-related pleural diseases from MPM, and the SUVmax in benign asbestos-related pleural diseases may reflect changes in pleural inflammation.

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