Oxford Medical Case Reports

Our medical research library holds 5 studies published in Oxford Medical Case Reports (2014–2025). Each entry links to the study's record on PubMed and, where there is one, to the publisher's page and a free full text. 4 have an abstract, the authors' own summary as PubMed records it: open "Abstract" to read it.

About the journal

• Publisher: Published by Oxford University Press and JSCR Publishing Ltd
• Published: 2014 to the present, England
• Language: English
• ISSN: 2053-8855 (electronic)
• Its record in the NLM Catalog

2020s

• Metastatic spread of pleural mesothelioma to the peritoneum and gallbladder presenting as recurrent acute cholecystitis. M. Fouad, A.M. Zaitoun, D.N. Lobo. 2025;2025(6):omaf082. Case report PubMed · Publisher · Free full text

  Abstract

  Malignant pleural mesothelioma, a rare, aggressive cancer primarily associated with asbestos exposure, is characterised by poor prognosis and limited treatment options. Distant metastases are uncommon, and peritoneal involvement is rare, while metastasis to the gallbladder is extremely unusual. We report the case of a patient with malignant pleural mesothelioma undergoing immunotherapy with nivolumab and ipilimumab, who developed recurrent acute cholecystitis. Imaging revealed features of acute cholecystitis with gallstones. She eventually underwent a laparoscopic cholecystectomy because immunotherapy could not be continued in the presence of infection. Histopathological and immunohistochemical analysis confirmed metastatic epithelioid mesothelioma. The gallbladder metastasis was likely haematogenous or from peritoneal seeding, rather than direct spread. This case underscores the importance of a high index of suspicion when evaluating atypical presentations of mesothelioma, particularly in the context of immunotherapy.

  © The Author(s) 2025. Published by Oxford University Press.

• A case of malignant mesothelioma in a young patient with childhood leukaemia who had received total body irradiation. R. Hayat, S. Ahmed, R. Badiger, et al. 2023;2023(5):omac151. Case report PubMed · Publisher · Free full text

  Abstract

  This case report explores a 34-year-old male diagnosed with mesothelioma who had no known risk factors. The patient initially was treated for empyema with antibiotics but later represented to hospital with worsening symptoms. He underwent a surgical Video-assisted thoracoscopic surgery procedure and lung biopsy, which revealed a diagnosis of mesothelioma. The young age of the patient as well as absence of significant risk factors for mesothelioma made the diagnosis unexpected. The patient had total body irradiation (TBI) therapy for leukaemia as a child, which increases the risk of developing cancer. However, there are limited studies exploring the risk of pleural mesothelioma post-TBI. Young patients who represent to hospital, with limited response to initial treatment, and suspicious radiological features should be considered for lung biopsy to reduce the risk of a missed diagnosis. Patients with a background of TBI should also be considered for follow-up to monitor for any subsequent malignancy.

  Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2022.

• Localized malignant peritoneal mesothelioma presenting hepatohilar giant mass. O. Kinoshita. 2022;2022(10):omac110. Case report PubMed · Publisher · Free full text

2010s

• Localized malignant pleural mesothelioma with renal metastasis. S.J. Zardawi, B.T. Li, M.G. Zauderer, et al. 2015;2015(1):170-2. Case report PubMed · Publisher · Free full text

  Abstract

  Localized malignant pleural mesothelioma (LMM) is a rare subset of malignant pleural mesothelioma. Its epidemiology, biology, natural history and optimal treatment are poorly understood. We report a case of LMM treated aggressively with complete surgical resection and adjuvant radiotherapy, but subsequently complicated by local chest wall recurrence and solitary metastasis to the kidney. This case is examined in the context of a small number of cases of LMM in the literature to emphasize the existence of this rare disease entity, their unusual biological behaviour and the need for further tumour molecular and genomic research.

• Desmoplastic malignant mesothelioma of the peritoneum. B. Badak, O. Turk, E. Ates, et al. 2014;2014(3):49-51. Case report PubMed · Publisher · Free full text

  Abstract

  Malignant mesothelioma is an uncommon neoplasm arising in body cavities lined by the mesothelium. Immunohistochemical stains are useful for making a diagnosis, but the correct combination of antibodies as should be selected in a comprehensive assessment. A peritoneal origin combined with desmoplastic histology is an extremely rare disease entity. Here, we report a case of the primary peritoneal malignant mesothelioma. A 53-year-old man admitted to the hospital with abdominal distension and pelvic pain. In laparotomy, peritonitis carcinomatosa situation was exposed. Multiple biopsies were taken from omentum, peritoneum and fascia. Calretinin, WT-1, D2-40, keratin 5/6, mesothelin, keratin 7, keratin 20, CD99, CEA, smooth muscle actin, desmin, CD34 and S-100 were negative. With these findings tumor was evaluated as desmoplastic malignant mesothelioma of the peritoneum. Currently, no established standard treatments for malignant peritoneal mesothelioma, but early diagnosis by exploratory laparotomy followed by chemotherapy may have contributed to longer survival for patients.

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