Systematic Reviews and Meta-Analyses on Asbestos

PubMed, the National Library of Medicine's index of medical journals, labels every article with its publication type. 251 studies in our library are labeled as reviews that search for every study on a question by a stated method, and meta-analyses, which combine the results of several studies statistically. The labels are NLM's, not ours. Each entry links to the study on PubMed and to its journal's page in our library, where you can read the abstract.

2020s

• A Multimodal Framework to Guide Solid Tumor Indications for Natural Killer Cell-Based Therapy. L. Chiossone, V. Picant, Q. Barbier, et al. European Journal of Immunology 2026;56(9):e70283. Systematic review PubMed · Publisher · Free full text

• Carcinoids of the lung caused by exogenous noxious agents: a scoping review. S. Kilo, C. Schröder, L. Frei-Stuber, et al. European Respiratory Review 2026;35(182). PubMed · Publisher · Free full text

• Diagnostic performance and safety of image-guided pleural biopsy and medical thoracoscopy for undiagnosed exudative pleural effusion: a systematic review and network meta-analysis. S. Lyu, Z. Zheng, L. Liao, et al. European Respiratory Review 2026;35(180). Systematic review PubMed · Publisher · Free full text

• Exposure to Occupational Inhalants and the Risk of Developing Rheumatoid Arthritis: A Systematic Review and Meta-Analysis. Q. Liu, X. Song, E. Mauro, et al. Arthritis & Rheumatology 2026;78(4):830-847. Systematic review · Meta-analysis PubMed · Publisher · Free full text

• Molecular Systems Architecture of Fibrotic Lung Microenvironment in Idiopathic Pulmonary Fibrosis. V.A.S. Ayyadurai, Y. Manoharan, P. Deonikar. Cells 2026;15(15). Systematic review PubMed · Publisher · Free full text

• Risk for second primary malignancies in patients with multiple myeloma: a systematic review and meta-analysis. Y. Tian, L. Su, Y. Li, et al. Frontiers in Oncology 2026;16:1770120. Systematic review PubMed · Publisher · Free full text

• Surveillance of Non-Malignant Asbestos-Related Diseases in an Exposed Population: A Scoping Review. C. de la Pava-Cortés, E. Peña Torres, T. Driscoll, et al. Annals of Global Health 2026;92(1):19. PubMed · Publisher · Free full text

• Asbestos Exposure and Leukemia Incidence: A Systematic Review and Meta-analysis. K. Dodos, T.V. Kalamara, P. Papalexis, et al. In Vivo 2025;39(5):2739-2751. Systematic review · Meta-analysis PubMed · Publisher · Free full text

• Biomarkers Suitable for Early Detection of Intrathoracic Cancers in Primary Care: A Systematic Review. W. Hamad, B. Grigore, H. Walford, et al. Cancer Epidemiology, Biomarkers & Prevention 2025;34(1):19-34. Systematic review PubMed · Publisher · Free full text

• Cancer Risk Prediction Using Machine Learning for Supporting Early Cancer Diagnosis in Symptomatic Patients: A Systematic Review of Model Types. F. Pennisi, S. Borlini, H. Harrison, et al. Cancer Medicine 2025;14(24):e71463. Systematic review PubMed · Publisher · Free full text

• Efficacy and safety of PD-1/PD-L1 and CTLA-4 immune checkpoint inhibitors in the treatment of diffuse pleural mesothelioma: a systematic review and meta-analysis. P. Sun, D. Song, N. Ma, et al. Frontiers in Immunology 2025;16:1578746. Systematic review · Meta-analysis PubMed · Publisher · Free full text

• Evaluation of imaging techniques for early detection of intrathoracic cancers in symptomatic patients in primary care: a systematic review. B. Grigore, J.L. Peters, W. Hamad, et al. BMJ Open 2025;15(8):e091435. Systematic review PubMed · Publisher · Free full text

• Examining the Environmental Ramifications of Asbestos Fiber Movement Through the Water-Soil Continuum: A Review. G.Z. Macher, A. Torma, D. Beke. International Journal of Environmental Research and Public Health 2025;22(4). Systematic review PubMed · Publisher · Free full text

• Factors associated with lung cancer among firefighters: a systematic literature review. A.W. Kang, N.S. Lui. BMC Public Health 2025;25(1):281. Systematic review PubMed · Publisher · Free full text

• Hyperthermic intrathoracic chemotherapy in patients with malignant pleural mesothelioma after cytoreductive surgical procedures: a systematic review. H.H. Elsayed, M.E.E. Elanany, M.T. ElSayegh, et al. World Journal of Surgical Oncology 2025;23(1):132. Systematic review PubMed · Publisher · Free full text

• Inhalational exposures associated with risk of interstitial lung disease: a systematic review and meta-analysis. C.T. Lee, S.A. Gandhi, S. Elmrayed, et al. Thorax 2025;80(12):918-926. Systematic review · Meta-analysis PubMed · Publisher · Free full text

• Is ADC a rising star in solid tumor? An umbrella review of systematic reviews and meta-analyses. H. Wei, Y. Zhang, Y. Lu, et al. BMC Cancer 2025;25(1):380. Systematic review PubMed · Publisher · Free full text

• Mapping three decades of air pollution-lung cancer research: trends, hotspots, and networks (1990-2025). H. Fan, L. Wang, L. Zhai, et al. Frontiers in Oncology 2025;15:1698246. Systematic review PubMed · Publisher · Free full text

• National Guidelines for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Peritoneal Malignancies: A Worldwide Systematic Review and Recommendations of Strength Analysis. M. Tonello, C. Cenzi, E. Pizzolato, et al. Annals of Surgical Oncology 2025;32(8):5795-5806. Systematic review PubMed · Publisher · Free full text

• Occupational asbestos exposure and gastrointestinal cancers: systematic review and meta-analyses. M. Koehoorn, C.B. McLeod, J. Fan, et al. Occupational and Environmental Medicine 2025;81(12):639-646. Systematic review · Meta-analysis PubMed · Publisher

• Performance of the Monoclonal Antibody B72.3 in Diagnosis of Malignant Carcinomatous Serous Effusions-A Systematic Review and Meta-Analysis of Diagnostic Performance. A.H. Lin, M. Hsu, J.K.M. Ng, et al. Cytopathology 2025;36(4):399-407. Systematic review · Meta-analysis PubMed · Publisher · Free full text

• Predicting Mesothelioma Using Artificial Intelligence: A Scoping Review of Common Models and Applications. M. Ram, M.R. Afrash, K. Moulaei, et al. Technology in Cancer Research & Treatment 2025;24:15330338251341053. PubMed · Publisher · Free full text

• Psychological Distress in Patients With Asbestos-Related Diseases and Their Families: A Systematic Literature Review. I.G. Franzoi, M.D. Sauta, M. Bonafede, et al. Psycho-oncology 2025;34(1):e70051. Systematic review PubMed · Publisher · Free full text

• Risk factors for postoperative acute kidney injury after cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy: a meta-analysis and systematic review. D. Chen, Y. Ma, J. Li, et al. World Journal of Surgical Oncology 2025;23(1):40. Systematic review · Meta-analysis PubMed · Publisher · Free full text

• The public health impacts of mining in Australia. J. Cortes-Ramirez, R.N. Michael, L.M. Toms, et al. The Medical Journal of Australia 2025;223(10):541-549. Systematic review PubMed · Publisher · Free full text

• The role of MicroRNAs as early biomarkers of asbestos-related lung cancer: A systematic review and meta-analysis. D. Mukhopadhyay, P. Cocco, S. Orrù, et al. Pulmonology 2025;31(1):2416792. Meta-analysis · Systematic review PubMed · Publisher

• Volatile organic compounds in exhaled human breath for the diagnosis of malignant pleural mesothelioma: a meta-analysis. T. Zhao, X. Hu, M. Peng, et al. Frontiers in Oncology 2025;15:1537767. Systematic review PubMed · Publisher · Free full text

• A systematic review of literature on Insulin-like growth factor-2-mediated hypoglycaemia in non-islet cell tumours. F. Ata, H. Choudry, A.A. Khan, et al. Endocrinology, Diabetes & Metabolism 2024;7(2):e00471. Systematic review PubMed · Publisher · Free full text

• An umbrella review of the evidence associating occupational carcinogens and cancer risk at 19 anatomical sites. X. Xiong, S. Zhang, X. Liao, et al. Environmental Pollution 2024;345:123531. Meta-analysis · Systematic review PubMed · Publisher

• Genes and Pathways Involved in the Progression of Malignant Pleural Mesothelioma: A Meta-analysis of Genome-Wide Expression Studies. A. Mejia-Garcia, D.A. Bonilla, C.M. Ramirez, et al. Biochemical Genetics 2024;62(1):352-370. Meta-analysis PubMed · Publisher

• Health Effects of Occupational and Environmental Exposures to Nuclear Power Plants: A Meta-Analysis and Meta-Regression. R.T. Lin, H. Boonhat, Y.Y. Lin, et al. Current Environmental Health Reports 2024;11(3):329-339. Meta-analysis · Review PubMed · Publisher · Free full text

• Human Exposure to Asbestos in Central Asian Countries and Health Effects: A Narrative Review. Z. Kurzhunbaeva, K. Dzhusupov, A. Spinazzè, et al. La Medicina del Lavoro 2024;115(6):e2024042. Systematic review PubMed · Publisher · Free full text

• Living with mesothelioma: a systematic review of mental health and well-being impacts and interventions for patients and their informal carers. V. Sherborne, S. Ejegi-Memeh, A.M. Tod, et al. BMJ Open 2024;14(6):e075071. Systematic review PubMed · Publisher · Free full text

• Lung cancer risk and occupational pulmonary fibrosis: systematic review and meta-analysis. J. Krabbe, K.M. Steffens, S. Drießen, et al. European Respiratory Review 2024;33(171). Meta-analysis · Systematic review PubMed · Publisher · Free full text

• Mesothelioma among seamen: a systematic review and meta-analysis. M. Rota, A. Viscardi, F. Maghin, et al. European Journal of Cancer Prevention 2024;33(5):438-447. Systematic review · Meta-analysis PubMed · Publisher

• Meta-Analysis of Integrated Proteomic and Transcriptomic Data Discerns Structure-Activity Relationship of Carbon Materials with Different Morphologies. V.I. Dumit, Y.C. Liu, A. Bahl, et al. Advanced Science 2024;11(9):e2306268. Meta-analysis PubMed · Publisher · Free full text

• Occupational asbestos exposure and risk of esophageal cancer: A systematic review and meta-analysis. M.S. Seyyedsalehi, P. Boffetta. International Journal of Cancer 2024;154(11):1920-1929. Meta-analysis · Systematic review PubMed · Publisher

• Personal protective equipment for preventing asbestos exposure in workers. L. Belackova, J.H. Verbeek, J.L. Hoving, et al. The Cochrane Database of Systematic Reviews 2024;5(5):CD015158. Meta-analysis · Review PubMed · Publisher · Free full text

• Rehabilitation for Functioning and Quality of Life in Patients with Malignant Pleural Mesothelioma: A Scoping Review. L. Lippi, A. de Sire, V. Aprile, et al. Current Oncology 2024;31(8):4318-4337. PubMed · Publisher · Free full text

• Review of epidemiological and toxicological studies on health effects from ingestion of asbestos in drinking water. J. Go, N. Farhat, K. Leingartner, et al. Critical Reviews in Toxicology 2024;54(10):856-894. Systematic review PubMed · Publisher

• Revisiting the association between pretreatment thrombocytosis and cancer survival outcomes: an umbrella review of meta-analyses. C. Shu, X. Wang, C. Li, et al. BMC Cancer 2024;24(1):1246. Systematic review PubMed · Publisher · Free full text

• Safety and efficacy of PD-1/PD-L1 immune checkpoint inhibitors in patients with pre-treated advanced stage malignant mesothelioma: a systematic review and meta-analysis. A. Zafar, A.A. Rashid, A. Moeed, et al. BMC Cancer 2024;24(1):1353. Systematic review · Meta-analysis PubMed · Publisher · Free full text

• Scoping review of exposure questionnaires and surveys in interstitial lung disease. H. Barnes, S. Elmrayed, C.M. Barber, et al. BMJ Open Respiratory Research 2024;11(1). PubMed · Publisher · Free full text

• Structural Racism and Lung Cancer Risk: A Scoping Review. S.N. Bonner, R. Curley, K. Love, et al. JAMA Oncology 2024;10(1):122-128. PubMed · Publisher

• The diagnostic utility of glycosaminoglycans (GAGs) in the early detection of cancer: a systematic review. S. Douglah, R. Khalil, R. Kanaan, et al. PeerJ 2024;12:e18486. Systematic review PubMed · Publisher · Free full text

• The Impact of Occupational Exposures on Chronic Rhinosinusitis: A Scoping Review. A.S. Monk, C.P. Worden, E.H. Benaim, et al. Exploration of Asthma & Allergy 2024;2(4):301-318. PubMed · Publisher · Free full text

• Asbestos Consumption and Malignant Mesothelioma Mortality Trends in the Major User Countries. C. Gariazzo, A. Gasparrini, A. Marinaccio. Annals of Global Health 2023;89(1):11. Meta-analysis PubMed · Publisher · Free full text

• Asbestos exposure and small cell lung cancer: Systematic review and meta-analysis. T. Curiel-García, J. Rey-Brandariz, L. Varela-Lema, et al. Journal of Occupational and Environmental Hygiene 2023;20(10):427-438. Meta-analysis · Systematic review PubMed · Publisher

• Association between Asbestos Exposure and the Incidence of Kidney Cancer: a Weight-of-Evidence Evaluation and Meta-analysis. F.W. Lee, Y.H. Chen, N.D. Tran, et al. Current Environmental Health Reports 2023;10(4):394-409. Meta-analysis · Review PubMed · Publisher

• Cytoreductive surgery with hyperthermic intrathoracic chemotherapy for malignant pleural mesothelioma: a systematic review. A.G. Dawson, K. Kutywayo, S.B. Mohammed, et al. Thorax 2023;78(4):409-417. Systematic review PubMed · Publisher

• Diagnostic value of combination of biomarkers for malignant pleural mesothelioma: a systematic review and meta-analysis. M. Zhu, Z. Lu, H. Guo, et al. Frontiers in Oncology 2023;13:1136049. Systematic review PubMed · Publisher · Free full text

• Efficacy and safety profile of combining antiangiogenic agents with chemotherapy in patients with advanced malignant pleural mesothelioma: A systematic review and meta-analysis of randomized controlled trials. W. Tian, Q. Guo, D. Fu, et al. PloS One 2023;18(12):e0295745. Meta-analysis · Systematic review PubMed · Publisher · Free full text

• Endocrine-disrupting chemicals (EDCs) and cancer: new perspectives on an old relationship. R. Modica, E. Benevento, A. Colao. Journal of Endocrinological Investigation 2023;46(4):667-677. Meta-analysis · Review PubMed · Publisher

• Molecular alterations and potential actionable mutations in peritoneal mesothelioma: a scoping review of high-throughput sequencing studies. M.V. Dietz, J.P. van Kooten, M.S. Paats, et al. ESMO Open 2023;8(4):101600. PubMed · Publisher · Free full text

• Occupational asbestos exposure and ovarian cancer: updated systematic review. F. Turati, M. Rossi, A. Spinazzè, et al. Occupational Medicine 2023;73(9):532-540. Systematic review PubMed · Publisher

• Occupational asbestos exposure and urinary bladder cancer: a systematic review and meta-analysis. N. Franco, A. Godono, M. Clari, et al. World Journal of Urology 2023;41(4):1005-1015. Meta-analysis · Systematic review PubMed · Publisher · Free full text

• Pre-treatment soluble PD-L1 as a predictor of overall survival for immune checkpoint inhibitor therapy: a systematic review and meta-analysis. Á. Széles, T. Fazekas, S. Váncsa, et al. Cancer Immunology, Immunotherapy 2023;72(5):1061-1073. Meta-analysis · Systematic review PubMed · Publisher · Free full text

• Quantitative Assessment of Asbestos Fibers in Abdominal Organs: A Scoping Review. Y. Caraballo-Arias, F. Roccuzzo, F. Graziosi, et al. La Medicina del Lavoro 2023;114(6):e2023048. PubMed · Publisher · Free full text

• Quantitative assessment of asbestos fibers in some normal and pathological extra-abdominal tissues-a scoping review. F. Graziosi, P. Caffaro, M. Bonetti, et al. Journal of Occupational Medicine and Toxicology 2023;18(1):24. PubMed · Publisher · Free full text

• Quantitative assessment of mesothelioma and lung cancer risk based on Phase Contrast Microscopy (PCM) estimates of fibre exposure: an update of 2000 asbestos cohort data. L. Darnton. Environmental Research 2023;230:114753. Meta-analysis PubMed · Publisher

• The prevalences and levels of occupational exposure to dusts and/or fibres (silica, asbestos and coal): A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury. V. Schlünssen, D. Mandrioli, F. Pega, et al. Environment International 2023;178:107980. Meta-analysis · Systematic review PubMed · Publisher

• Traditional Treatment Approaches and Role of Immunotherapy in Lung Malignancy and Mesothelioma. M.T. Tamanna, C. Egbune. Cancer Treatment and Research 2023;185:79-89. Meta-analysis PubMed · Publisher

• Work-related respiratory health conditions among construction workers: a systematic narrative review. E.F. Boadu, S.R. Okeke, C. Boadi, et al. BMJ Open Respiratory Research 2023;10(1). Systematic review PubMed · Publisher · Free full text

• A MUC5B Gene Polymorphism, rs35705950-T, Confers Protective Effects Against COVID-19 Hospitalization but Not Severe Disease or Mortality. A. Verma, J. Minnier, E.S. Wan, et al. American Journal of Respiratory and Critical Care Medicine 2022;206(10):1220-1229. Meta-analysis PubMed · Publisher · Free full text

• Cholangiocarcinoma Attributed to Occupation: A Systematic Reviews. A. Seeherunwong, N. Chaiear, N. Khuntikeo, et al. Asian Pacific Journal of Cancer Prevention 2022;23(6):1837-1845. Systematic review PubMed · Publisher · Free full text

• Environmental exposure to asbestos and the risk of lung cancer: a systematic review and meta-analysis. K. Kwak, D. Kang, D. Paek. Occupational and Environmental Medicine 2022;79(3):207-214. Meta-analysis · Systematic review PubMed · Publisher

• Exposure to silicates and systemic autoimmune-related outcomes in rodents: a systematic review. L.M.F. Janssen, M. Ghosh, F. Lemaire, et al. Particle and Fibre Toxicology 2022;19(1):4. Systematic review PubMed · Publisher · Free full text

• Fiber burden and asbestos-related diseases: an umbrella review. J.M. Ramada Rodilla, B. Calvo Cerrada, C. Serra Pujadas, et al. Gaceta Sanitaria 2022;36(2):173-183. Systematic review PubMed · Publisher · Free full text

• LAMC2 as a prognostic biomarker in human cancer: a systematic review and meta-analysis. T. Fu, J.X. Liu, J. Xie, et al. BMJ Open 2022;12(11):e063682. Meta-analysis · Systematic review PubMed · Publisher · Free full text

• Novel and Future Treatment Options in Mesothelioma: A Systematic Review. D. Štrbac, V. Dolžan. International Journal of Molecular Sciences 2022;23(4). Systematic review PubMed · Publisher · Free full text

• Population pharmacokinetic models of anti-PD-1 mAbs in patients with multiple tumor types: A systematic review. J. Shang, L. Huang, J. Huang, et al. Frontiers in Immunology 2022;13:871372. Systematic review PubMed · Publisher · Free full text

• Preliminary validation of a questionnaire assessing psychological distress in caregivers of patients with malignant mesothelioma: Mesothelioma Psychological Distress Tool-Caregivers. M. Bonafede, C. Chiorri, D. Azzolina, et al. Psycho-oncology 2022;31(1):122-129. Systematic review PubMed · Publisher

• Prognostic impact of pleural effusion in patients with malignancy: A systematic review and meta-analysis. Y. Yang, J. Du, Y.S. Wang, et al. Clinical and Translational Science 2022;15(6):1340-1354. Meta-analysis · Systematic review PubMed · Publisher · Free full text

• Quantitative Assessment of Asbestos Fibers in Normal and Pathological Peritoneal Tissue-A Scoping Review. Y. Caraballo-Arias, C. Zunarelli, P. Caffaro, et al. Life 2022;12(12). PubMed · Publisher · Free full text

• Quantitative Assessment of Asbestos Fibers in Normal and Pathological Pleural Tissue-A Scoping Review. Y. Caraballo-Arias, P. Caffaro, P. Boffetta, et al. Life 2022;12(2). PubMed · Publisher · Free full text

• Relationship between exposure to ionizing radiation and mesothelioma risk: A systematic review of the scientific literature and meta-analysis. G. Visci, E. Rizzello, C. Zunarelli, et al. Cancer Medicine 2022;11(3):778-789. Meta-analysis · Systematic review PubMed · Publisher · Free full text

• Role of Beta-Carotene in Lung Cancer Primary Chemoprevention: A Systematic Review with Meta-Analysis and Meta-Regression. J. Kordiak, F. Bielec, S. Jabłoński, et al. Nutrients 2022;14(7). Meta-analysis · Systematic review PubMed · Publisher · Free full text

  In plain English

  This systematic review and meta-analysis pooled randomized controlled trials of beta-carotene supplements for preventing lung cancer. It included eight trials with 167,141 participants in the USA, Finland, the UK and China, published by November 2021. One trial group (CARET) was 4,060 male asbestos workers in the USA, randomly assigned to placebo or to 30 mg beta-carotene daily plus retinol. Every trial also tested other substances, though some participants in some trials took beta-carotene without them. Overall, people given beta-carotene had a higher relative risk (RR) of lung cancer than those given placebo: 1.16 (95% CI 1.06–1.26). For smokers and asbestos workers combined, the RR was 1.21 (95% CI 1.08–1.35). The asbestos-worker group on its own had an RR of 1.40 (95% CI 0.95–2.07), a range that includes no difference. No statistically significant link was found between dose and risk. The authors concluded that beta-carotene has a negative effect on lung cancer risk in smokers and asbestos workers. They noted that because other antioxidants were also given, the effect may not come from beta-carotene alone.

  We wrote this plain-English summary from the full article with the help of AI, and a second AI model checked each sentence against the article. It is not the authors' wording; the abstract and the article are their own account.

• Scoping Review of 5 Common Occupational Cancers and Their Related Exposures. A. Naghibzadeh-Tahami, Y. Khosravi, M. Es'haghi, et al. Medical Journal of the Islamic Republic of Iran 2022;36:84. PubMed · Publisher · Free full text

• Sensitivity and complications of thoracentesis and thoracoscopy: a meta-analysis. G. Martinez-Zayas, S. Molina, D.E. Ost. European Respiratory Review 2022;31(166). Systematic review · Meta-analysis PubMed · Publisher · Free full text

• Systematic review of the scientific evidence of the pulmonary carcinogenicity of talc. H.N. Lynch, D.J. Lauer, W.J. Thompson, et al. Frontiers in Public Health 2022;10:989111. Systematic review PubMed · Publisher · Free full text

• The association between occupational asbestos exposure with the risk of incidence and mortality from prostate cancer: a systematic review and meta-analysis. A. Godono, M. Clari, N. Franco, et al. Prostate Cancer and Prostatic Diseases 2022;25(4):604-614. Meta-analysis · Systematic review PubMed · Publisher

• Can YKL-40 be used as a biomarker for interstitial lung disease?: A systematic review and meta-analysis. X. Tong, Y. Ma, T. Liu, et al. Medicine 2021;100(17):e25631. Meta-analysis · Systematic review PubMed · Publisher · Free full text

• Cancer Incidence and Mortality among Firefighters: An Overview of Epidemiologic Systematic Reviews. E. Laroche, S. L'Espérance. International Journal of Environmental Research and Public Health 2021;18(5). Systematic review PubMed · Publisher · Free full text

• Cancer Incidence and Mortality among Petroleum Industry Workers and Residents Living in Oil Producing Communities: A Systematic Review and Meta-Analysis. F.M. Onyije, B. Hosseini, K. Togawa, et al. International Journal of Environmental Research and Public Health 2021;18(8). Meta-analysis · Systematic review PubMed · Publisher · Free full text

• Clinical utility of diagnostic biomarkers in malignant pleural mesothelioma: a systematic review and meta-analysis. E. Schillebeeckx, J.P. van Meerbeeck, K. Lamote. European Respiratory Review 2021;30(162). Meta-analysis · Systematic review PubMed · Publisher · Free full text

• DNA Methylation as a Diagnostic Biomarker for Malignant Mesothelioma: A Systematic Review and Meta-Analysis. J. Vandenhoeck, J.P. van Meerbeeck, E. Fransen, et al. Journal of Thoracic Oncology 2021;16(9):1461-1478. Meta-analysis · Systematic review PubMed · Publisher

• Efficacy of Immune Checkpoint Inhibitors in Rare Tumours: A Systematic Review. F. Petrelli, F. Consoli, A. Ghidini, et al. Frontiers in Immunology 2021;12:720748. Meta-analysis · Systematic review PubMed · Publisher · Free full text

• Matrix Metalloproteinases as Biomarkers and Treatment Targets in Mesothelioma: A Systematic Review. D. Štrbac, V. Dolžan. Biomolecules 2021;11(9). Systematic review PubMed · Publisher · Free full text

• Meta-Analysis of the Association between Asbestos Exposure and Esophageal Cancer. C.W. Wu, H.Y. Chuang, D.L. Tsai, et al. International Journal of Environmental Research and Public Health 2021;18(21). Meta-analysis PubMed · Publisher · Free full text

• Methodological issues in descriptive environmental epidemiology. The example of study Sentieri. C. Ciocan, N. Franco, E. Pira, et al. La Medicina del Lavoro 2021;112(1):15-33. Meta-analysis · Systematic review PubMed · Publisher · Free full text

• Occupational Asbestos Exposure and Kidney Cancer: Systematic Review and Meta-analysis of Cohort Studies. C.C.Y. Pang, K. Phan, M.N. Karim, et al. Annals of Work Exposures and Health 2021;65(3):255-265. Meta-analysis · Systematic review PubMed · Publisher · Free full text

• Occupational exposure to asbestos and risk of kidney cancer: an updated meta-analysis. C. Zunarelli, A. Godono, G. Visci, et al. European Journal of Epidemiology 2021;36(9):927-936. Meta-analysis · Systematic review PubMed · Publisher · Free full text

• Prognostic Role of Programmed Cell Death 1 Ligand 1 in Resectable Pleural Mesothelioma. H.S. Lee, M. Hamaji, N. Palivela, et al. The Annals of Thoracic Surgery 2021;112(5):1575-1583. Meta-analysis PubMed · Publisher

• Prophylactic irradiation of tracts in patients with malignant pleural mesothelioma: A systematic review and meta-analysis of randomized trials. C.C. Lee, Y.Y. Soon, B. Vellayappan, et al. Critical Reviews in Oncology/hematology 2021;160:103278. Meta-analysis · Systematic review PubMed · Publisher

• Solitary pulmonary nodule malignancy predictive models applicable to routine clinical practice: a systematic review. M. Senent-Valero, J. Librero, M. Pastor-Valero. Systematic Reviews 2021;10(1):308. Systematic review PubMed · Publisher · Free full text

• The role of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in the treatment of peritoneal carcinomatosis: a systematic review including evidence from Japan. T. Kitai. Surgery Today 2021;51(7):1085-1098. Systematic review PubMed · Publisher

• Understanding the palliative care needs and experiences of people with mesothelioma and their family carers: An integrative systematic review. M. Harrison, C. Gardiner, B. Taylor, et al. Palliative Medicine 2021;35(6):1039-1051. Systematic review PubMed · Publisher · Free full text

• Colorectal cancer and asbestos exposure-an overview. Q. Huang, Y.J. Lan. Industrial Health 2020;58(3):200-211. Meta-analysis PubMed · Publisher · Free full text

• Differential Diagnosis of Epithelioid Malignant Mesothelioma With Lung and Breast Pleural Metastasis: A Systematic Review Compared With a Standardized Panel of Antibodies-A New Proposal That May Influence Pathologic Practice. N. Le Stang, L. Burke, G. Blaizot, et al. Archives of Pathology & Laboratory Medicine 2020;144(4):446-456. Systematic review PubMed · Publisher

• Disease-Related Outcomes and Toxicities of Intensity Modulated Radiation Therapy After Lung-Sparing Pleurectomy for Malignant Pleural Mesothelioma: A Systematic Review. R. Patel, E.B. Ludmir, J.A. Miccio, et al. Practical Radiation Oncology 2020;10(6):423-433. Systematic review PubMed · Publisher

• Drugs for preventing lung cancer in healthy people. M. Cortés-Jofré, J.R. Rueda, C. Asenjo-Lobos, et al. The Cochrane Database of Systematic Reviews 2020;3(3):CD002141. Meta-analysis · Systematic review PubMed · Publisher · Free full text

• Environmental and ecological factors of stomach cancer incidence and mortality: a systematic review study on ecological studies. S. Khazaei, A. Mohammadbeigi, E. Jenabi, et al. Reviews on Environmental Health 2020;35(4):443-452. Systematic review PubMed · Publisher

• Evaluation of Confounding and Selection Bias in Epidemiological Studies of Populations Exposed to Low-Dose, High-Energy Photon Radiation. M.K. Schubauer-Berigan, A. Berrington de Gonzalez, E. Cardis, et al. Journal of the National Cancer Institute. Monographs 2020;2020(56):133-153. Systematic review PubMed · Publisher · Free full text

• Exhaled Breath Analysis in Diagnosis of Malignant Pleural Mesothelioma: Systematic Review. Z.N. Töreyin, M. Ghosh, Ö. Göksel, et al. International Journal of Environmental Research and Public Health 2020;17(3). Systematic review PubMed · Publisher · Free full text

• Extrapleural pneumonectomies for pleural mesothelioma. E. Faccioli, A. Bellini, M. Mammana, et al. Expert Review of Respiratory Medicine 2020;14(1):67-79. Systematic review PubMed · Publisher

• Indwelling pleural catheter versus talc pleurodesis for malignant pleural effusion: a meta-analysis. M. Yeung, E.W. Loh, T.Y. Tiong, et al. Clinical & Experimental Metastasis 2020;37(4):541-549. Meta-analysis PubMed · Publisher

• Primary Melanoma of the Lung: A Systematic Review. P. Paliogiannis, A.M. Fara, G. Pintus, et al. Medicina 2020;56(11). Systematic review PubMed · Publisher · Free full text

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2010s

• About the diagnostic value of BAP-1 antibody in malignant pleural mesothelioma: a meta-analysis. M. Mlika, M. Zorgati, M. BenKhelil, et al. Journal of Immunoassay & Immunochemistry 2019;40(3):269-282. Meta-analysis PubMed · Publisher

• Asbestos exposure and malignant mesothelioma of the tunica vaginalis testis: a systematic review and the experience of the Apulia (southern Italy) mesothelioma register. L. Vimercati, D. Cavone, M.C. Delfino, et al. Environmental Health 2019;18(1):78. Systematic review PubMed · Publisher · Free full text

• Diagnostic value of soluble mesothelin-related peptides in pleural effusion for malignant pleural mesothelioma: An updated meta-analysis. R. Gao, F. Wang, Z. Wang, et al. Medicine 2019;98(14):e14979. Meta-analysis · Systematic review PubMed · Publisher · Free full text

• Retracted. Does exposure to asbestos cause prostate cancer? A systematic literature review and meta-analysis. R. Peng, F. Fang, Z. Chen, et al. Medicine 2019;98(3):e14108. Meta-analysis · Systematic review PubMed · Publisher · Free full text

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• A meta-analysis of airborne asbestos fiber concentrations from work with or around asbestos-containing floor tile. A.L. Perez, M.L. Nelson, T.J. Cheng, et al. International Journal of Occupational and Environmental Health 2018;24(3-4):134-148. Meta-analysis PubMed · Publisher · Free full text

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• Epidemiology of mesothelioma of the pericardium and tunica vaginalis testis. G. Mezei, E.T. Chang, F.S. Mowat, et al. Annals of Epidemiology 2017;27(5):348-359.e11. Systematic review PubMed · Publisher

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• Interventional options for the management of refractory cancer pain--what is the evidence?. P. Vayne-Bossert, B. Afsharimani, P. Good, et al. Supportive Care in Cancer 2016;24(3):1429-38. Systematic review PubMed · Publisher

• Mesothelioma among Motor Vehicle Mechanics: An Updated Review and Meta-analysis. D.H. Garabrant, D.D. Alexander, P.E. Miller, et al. The Annals of Occupational Hygiene 2016;60(1):8-26. Meta-analysis · Systematic review PubMed · Publisher

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• Risk of Lung Cancer in Workers Exposed to Benzidine and/or Beta-Naphthylamine: A Systematic Review and Meta-Analysis. K. Tomioka, K. Saeki, K. Obayashi, et al. Journal of Epidemiology 2016;26(9):447-58. Meta-analysis · Systematic review PubMed · Publisher · Free full text

• Well-Differentiated Papillary Mesothelioma of the Tunica Vaginalis: Case Report and Systematic Review of Literature. W.K. Tan, M.Y. Tan, W.S. Tan, et al. Clinical Genitourinary Cancer 2016;14(4):e435-9. Case report · Systematic review PubMed · Publisher

  In plain English

  This article combined a case report with a systematic review of published cases of well-differentiated papillary mesothelioma (WDPM) of the tunica vaginalis, the lining around the testis. As the authors describe, WDPM is considered benign, unlike malignant mesothelioma. Their patient was a 39-year-old Chinese man with a painless right scrotal swelling, no asbestos exposure, and 15 years of Plaster of Paris exposure. The tumor was removed with a wide margin, sparing the testis. Searching four databases through December 31, 2015, the authors found 24 cases and judged only 8 (including theirs) to be 'true' WDPM. Ages ranged 18 to 70 (mean 48); 7 of the 8 presented as a hydrocele. Five of the 8 reported no asbestos exposure; the other 3 lacked detailed exposure histories. No reported case had relapsed. The authors suggested asbestos may not be, or may only be a minor, risk factor for WDPM, though a contributing role remains plausible. They favored wide local excision over removing the testis, especially in younger patients, if clear margins were achievable, but advised removal when the tumor involves the testis.

  We wrote this plain-English summary from the full article with the help of AI, and a second AI model checked each sentence against the article. It is not the authors' wording; the abstract and the article are their own account.

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• Beta-carotene supplementation and cancer risk: a systematic review and metaanalysis of randomized controlled trials. N. Druesne-Pecollo, P. Latino-Martel, T. Norat, et al. International Journal of Cancer 2010;127(1):172-84. Meta-analysis · Systematic review PubMed · Publisher

  In plain English

  This was a systematic review and meta-analysis. It pooled 9 randomized controlled trials (13 publications, 182,323 participants) that compared beta-carotene supplements, given alone or with other antioxidants, against placebo for cancer incidence. Asbestos appears only as a feature of the populations studied. In two trials (ATBC and CARET), all participants were smokers or asbestos workers, and the authors analyzed these two trials together; asbestos workers were not analyzed separately. Across all trials, supplementation had no statistically significant effect on all cancers combined (RR 1.01; 95% CI 0.98–1.04). It also had no significant effect on pancreatic, colorectal, prostate, breast or skin cancers. Lung cancer risk was higher in supplemented people overall (RR 1.13; 95% CI 1.04–1.24). In the two smoker/asbestos-worker trials, supplemented participants had higher risks of lung cancer (RR 1.20; 95% CI 1.07–1.34), stomach cancer (RR 1.54; 95% CI 1.08–2.19) and all cancers (RR 1.08; 95% CI 1.01–1.15). Doses of 20 mg per day and above were also associated with more lung and stomach cancer. The authors said they could not tell whether dose or smoking/asbestos exposure mattered more. They concluded that beta-carotene supplements should not be recommended for primary cancer prevention.

  We wrote this plain-English summary from the full article with the help of AI, and a second AI model checked each sentence against the article. It is not the authors' wording; the abstract and the article are their own account.

• Diagnostic value of soluble mesothelin-related peptides for malignant mesothelioma: a meta-analysis. L. Luo, H.Z. Shi, Q.L. Liang, et al. Respiratory Medicine 2010;104(1):149-56. Meta-analysis · Systematic review PubMed · Publisher

  In plain English

  This was a meta-analysis. The authors pooled results from earlier published studies rather than testing patients themselves. They asked how accurately a blood test for soluble mesothelin-related peptides (SMRP) identifies malignant mesothelioma. They searched medical databases up to March 8, 2008, and included 11 English-language publications reporting 12 studies. These covered 717 people with mesothelioma and 2851 people without it. Some comparison groups were asbestos-exposed people or patients with benign asbestos-related disease. Pooled across studies, the test was positive in 64% of mesothelioma patients (sensitivity 0.64, 95% confidence interval 0.61 to 0.68). It was negative in 89% of people without mesothelioma (specificity 0.89, 0.88 to 0.90). Results differed significantly between studies. The test did less well at telling mesothelioma apart from other lung diseases than from healthy people. The authors judged overall accuracy (area under the curve 0.82) "not as high as expected" and found signs of possible publication bias. They concluded that the test plays a role in diagnosing malignant mesothelioma, but that results should be interpreted alongside clinical findings and conventional tests.

  We wrote this plain-English summary from the full article with the help of AI, and a second AI model checked each sentence against the article. It is not the authors' wording; the abstract and the article are their own account.

• Increased risk of high-grade hypertension with bevacizumab in cancer patients: a meta-analysis. V. Ranpura, B. Pulipati, D. Chu, et al. American Journal of Hypertension 2010;23(5):460-8. Meta-analysis · Systematic review PubMed · Publisher

2000s

• Occupational exposure to rock wool and glass wool and risk of cancers of the lung and the head and neck: a systematic review and meta-analysis. L. Lipworth, C. La Vecchia, C. Bosetti, et al. Journal of Occupational and Environmental Medicine 2009;51(9):1075-87. Meta-analysis · Systematic review PubMed · Publisher

• A meta-analysis of asbestos-related cancer risk that addresses fiber size and mineral type. D.W. Berman, K.S. Crump. Critical Reviews in Toxicology 2008;38 Suppl 1:49-73. Meta-analysis PubMed · Publisher

• A systematic review on the efficacy of cytoreductive surgery combined with perioperative intraperitoneal chemotherapy for diffuse malignancy peritoneal mesothelioma. T.D. Yan, L. Welch, D. Black, et al. Annals of Oncology 2007;18(5):827-34. Systematic review PubMed · Publisher

  In plain English

  This article was a systematic review, not a new study of patients. The authors searched six medical databases, up to May 2006, for studies of diffuse malignant peritoneal mesothelioma, a cancer of the abdominal lining. Studies had to use cytoreductive surgery (removal of visible tumor) combined with chemotherapy placed directly into the abdomen around the time of surgery. They included seven reports from six specialist centers, covering 240 patients. All seven were observational studies without a comparison group, and no randomized trials were found. Across the studies, median survival ranged from 34 to 92 months, and it was not reached in two studies. Survival ranged from 60% to 88% at 1 year, 43% to 65% at 3 years, and 29% to 59% at 5 years. Complication rates around the time of surgery ranged from 25% to 40%, and death rates around the time of surgery from 0% to 8%. The authors concluded that the studies showed better overall survival than historical patients treated with systemic chemotherapy and palliative surgery. They noted possible selection bias, small studies, short follow-up in some, and differing treatment plans. The review did not study asbestos exposure.

  We wrote this plain-English summary from the full article with the help of AI, and a second AI model checked each sentence against the article. It is not the authors' wording; the abstract and the article are their own account.

• First and subsequent asbestos exposures in relation to mesothelioma and lung cancer mortality. E. Pira, C. Pelucchi, P.G. Piolatto, et al. British Journal of Cancer 2007;97(9):1300-4. Meta-analysis PubMed · Publisher · Free full text

• Pemetrexed disodium in combination with cisplatin versus other cytotoxic agents or supportive care for the treatment of malignant pleural mesothelioma. J. Green, Y. Dundar, S. Dodd, et al. The Cochrane Database of Systematic Reviews 2007;2007(1):CD005574. Systematic review PubMed · Publisher · Free full text

  In plain English

  This was a Cochrane systematic review of trials of the chemotherapy drug pemetrexed combined with cisplatin in people with malignant pleural mesothelioma that could not be removed by surgery and who had not had chemotherapy before. It did not study asbestos exposure. Searches ran to October 2005. One randomised trial, EMPHACIS, met the criteria. In it, 448 patients received either pemetrexed plus cisplatin (226) or cisplatin alone (222). No studies compared pemetrexed with other regimens or with supportive care alone. In the trial's main analysis, median survival was 12.1 months with the combination and 9.3 months with cisplatin alone. Tumours partly shrank in 41.3% versus 16.7% of patients. Serious side effects, such as low white blood cell counts, were more common with the combination. Folic acid and vitamin B12 supplements lowered some of them. The authors concluded the combination with these supplements may improve survival in patients in good general condition. They noted several limits: only fitter patients took part, cisplatin alone is not universally accepted as standard care, and the doctors assessing outcomes knew which treatment patients received.

  We wrote this plain-English summary from the full article with the help of AI, and a second AI model checked each sentence against the article. It is not the authors' wording; the abstract and the article are their own account.

• Mesothelioma in patients with nonoccupational asbestos exposure. An evidence-based approach to causation assessment. A.M. Marchevsky, P. Harber, L. Crawford, et al. Annals of Diagnostic Pathology 2006;10(4):241-50. Systematic review PubMed · Publisher

• Meta-analysis of case-referent studies of specific environmental or occupational pollutants on lung cancer. H. Mahjub, G.H. Sadri. Indian Journal of Cancer 2006;43(4):169-73. Meta-analysis PubMed · Publisher

• Update of a meta-analysis on lung cancer and welding. D. Ambroise, P. Wild, J.J. Moulin. Scandinavian Journal of Work, Environment & Health 2006;32(1):22-31. Meta-analysis PubMed · Publisher

• Mesothelioma and lung cancer among motor vehicle mechanics: a meta-analysis. M. Goodman, M.J. Teta, P.A. Hessel, et al. The Annals of Occupational Hygiene 2004;48(4):309-26. Meta-analysis · Systematic review PubMed · Publisher

• Silicosis and smoking strongly increase lung cancer risk in silica-exposed workers. N. Kurihara, O. Wada. Industrial Health 2004;42(3):303-14. Meta-analysis · Review PubMed · Publisher

• Drugs for preventing lung cancer in healthy people. M. Caraballoso, M. Sacristan, C. Serra, et al. The Cochrane Database of Systematic Reviews 2003:CD002141. Systematic review PubMed · Publisher

• Lung cancer screening with low-dose CT. S. Diederich, D. Wormanns, W. Heindel. European Journal of Radiology 2003;45(1):2-7. Meta-analysis PubMed · Publisher

• Activity of chemotherapy and immunotherapy on malignant mesothelioma: a systematic review of the literature with meta-analysis. T. Berghmans, M. Paesmans, Y. Lalami, et al. Lung Cancer 2002;38(2):111-21. Meta-analysis · Systematic review PubMed · Publisher

• Respiratory cancer and exposure to man-made vitreous fibers: a systematic review. D. Berrigan. American Journal of Industrial Medicine 2002;42(4):354-62. Meta-analysis · Systematic review PubMed · Publisher

• Combination raltitrexed (Tomudex(R))-oxaliplatin: a step forward in the struggle against mesothelioma? The Institut Gustave Roussy experience with chemotherapy and chemo-immunotherapy in mesothelioma. K. Fizazi, R. Caliandro, P. Soulié, et al. European Journal of Cancer 2000;36(12):1514-21. Meta-analysis PubMed · Publisher

• Kidney cancer and occupational exposure to asbestos: a meta-analysis of occupational cohort studies. D. Sali, P. Boffetta. Cancer Causes & Control 2000;11(1):37-47. Meta-analysis PubMed · Publisher

• Occupational exposures and pancreatic cancer: a meta-analysis. I.A. Ojajärvi, T.J. Partanen, A. Ahlbom, et al. Occupational and Environmental Medicine 2000;57(5):316-24. Meta-analysis PubMed · Publisher · Free full text

1990s

• Cancer in asbestos-exposed occupational cohorts: a meta-analysis. M. Goodman, R.W. Morgan, R. Ray, et al. Cancer Causes & Control 1999;10(5):453-65. Meta-analysis PubMed · Publisher
• Synergy between asbestos and smoking on lung cancer risks. T.C. Erren, M. Jacobsen, C. Piekarski. Epidemiology 1999;10(4):405-11. Meta-analysis PubMed · Publisher
• A meta-analysis of painting exposure and cancer mortality. R. Chen, A. Seaton. Cancer Detection and Prevention 1998;22(6):533-9. Meta-analysis PubMed · Publisher
• A meta-analysis of epidemiologic studies of lung cancer in welders. J.J. Moulin. Scandinavian Journal of Work, Environment & Health 1997;23(2):104-13. Meta-analysis PubMed · Publisher
• A meta-analysis of the relation between cumulative exposure to asbestos and relative risk of lung cancer. T.L. Lash, E.A. Crouch, L.C. Green. Occupational and Environmental Medicine 1997;54(4):254-63. Meta-analysis PubMed · Publisher · Free full text
• Surveillance and intervention studies on respiratory cancers in asbestos-exposed workers. E. Merler, E. Buiatti, H. Vainio. Scandinavian Journal of Work, Environment & Health 1997;23(2):83-92. Systematic review PubMed · Publisher
• The lack of causality between asbestos and colorectal cancer. W. Weiss. Journal of Occupational and Environmental Medicine 1995;37(12):1364-73. Meta-analysis PubMed · Publisher
• A meta-analysis of colorectal cancer and asbestos exposure. D.M. Homa, D.H. Garabrant, B.W. Gillespie. American Journal of Epidemiology 1994;139(12):1210-22. Meta-analysis PubMed · Publisher
• Asbestos and colon cancer: a weight-of-the-evidence review. J.F. Gamble. Environmental Health Perspectives 1994;102(12):1038-50. Meta-analysis PubMed · Publisher · Free full text
• Exposure to stainless steel welding fumes and lung cancer: a meta-analysis. B. Sjögren, K.S. Hansen, H. Kjuus, et al. Occupational and Environmental Medicine 1994;51(5):335-6. Meta-analysis PubMed · Publisher · Free full text
• Attitudes about asbestos and lung cancer. R.W. Morgan. American Journal of Industrial Medicine 1992;22(3):437-41. Meta-analysis PubMed · Publisher
• Cigarette smoking, asbestos, and parenchymal opacities revisited. P. Blanc. Annals of the New York Academy of Sciences 1991;643:133-41. Meta-analysis PubMed · Publisher
• Re: Meta-analysis of asbestos and gastrointestinal cancer. R.W. Morgan. American Journal of Industrial Medicine 1991;19(3):407-11. Comment · Letter · Meta-analysis PubMed · Publisher
• Epidemiological evidence indicates asbestos causes laryngeal cancer. A.H. Smith, M.A. Handley, R. Wood. Journal of Occupational Medicine. 1990;32(6):499-507. Meta-analysis PubMed · Publisher

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